Abstract Second near‐infrared (NIR‐II) responsive hydrogels have shown significant potential in biomedical applications due to their excellent remote actuation property and the high tissue penetrations of NIR‐II light. Nevertheless, with a single light response may not meet diverse requirements complex conditions clinical applications. Here, novel multi‐responsive nanocomposite hydrogel enhanced suitability for controlled drug release is developed. This constructed by combining alginate...

Percutaneous pedicle screw instrumentation is a minimally invasive surgical technique; however, the effects of using percutaneous fixation in treating patients with spinal infections have not yet been well demonstrated. The aim this study, therefore, was to determine whether posterior superior traditional open approach pyogenic spondylodiscitis. We retrospectively reviewed data for 45 treated spondylodiscitis anterior debridement and interbody fusion followed by second-stage procedure...

Atypical subtrochanteric fracture and femoral have been considered to be rare complications related long-term bisphosphonates use. A reduced bone turnover rate may lead delayed healing. Limited data revealed that teriparatide treatment reverse the effect of effective in healing.We reviewed patients with atypical use between January 2008 December 2014. Thirteen female were enrolled. Radiographic findings compatible characteristics fracture. Surgical intervention was performed for all, advised...

The comparison of mortality and morbidity between distal femur (DF) hip fracture in the old age is rarely reported literature. We aim to analyze a nationwide database among elderly compare outcomes fractures United States.A retrospective analysis National Trauma Data Bank was queried 2007-2014 identify patients greater than 65 years age. Outcomes analyzed included in-hospital mortality, total hospital length stay(LOS), intensive care unit stay(ICU-LOS), ventilation use discharge disposition....

The highly (00l)-oriented 5 mol % Mn doped Pb0.5Sr0.5TiO3 films with remarkable ferroelectric properties (2Pr=27.1 μC/cm2 and 2Ec=55.5 kV/cm) were fabricated on LaNiO3 coated silicon substrates by chemical solution deposition. ac conductivity the dielectric response of at various temperatures studied. Hopping conduction accompanied relaxation low frequencies was observed. results can be correlated thermal-activated short range hopping localized charge carriers through trap sites separated...

The efficacy of green tea polyphenol infused with milk (GTPM) on skin integrity in correlation antioxidative status healthy adults was investigated. GTPM proved to be an effective antioxidant.

In this study, zinc oxide (ZnO) nanorod arrays as antibiotic agent carriers were grown on polyetheretherketone (PEEK) substrates using a chemical synthesis method. With the concentration of ammonium hydroxide in precursor solution kept at 4 M, ZnO with diameters range 100-400 nm and loading density 1.7 mg/cm

Case Series and Technical Note, Objective: UBS has been extensively used in open surgery. However, the use of during UBESS not reported literature. The aim this study was to describe a new spinal surgical technique using an ultrasonic bone scalpel (UBS) unilateral biportal endoscopic spine surgery (UBESS) report preliminary results technique. We enrolled patients diagnosed with lumbar stenosis who underwent single-level UBESS. All were followed up for more than 12 months. A laminotomy...

The use of indigo naturalis to treat psoriasis has proved effective in our previous clinical studies. present study was designed examine the anti-inflammatory effect primary cultured human umbilical vein endothelial cells (HUVECs). Pretreatment with extract attenuated TNF-α-induced increase Jurkat T cell adhesion HUVECs as well decreased protein and messenger (m)RNA expression levels vascular molecule-1 (VCAM-1) on HUVECs. Indigo also inhibited activator protein-1 (AP-1)/c-Jun, a critical...

The vacuum phenomenon within the intervertebral disc usually represents degeneration. There are no reports in English literature that focus on effect of an anterior surgical outcome same-segment spondylolisthesis. Patients with degenerative spondylolisthesis (DS) or isthmic (IS) who underwent a spinal surgery between January 2005 and December 2006 were reviewed. met certain criteria, including (1) only mono-segment spondylolisthesis, (2) gas air space segment preoperative radiographs, (3)...

7585 Background: Regorafenib is a novel diphenylurea oral multikinase inhibitor of angiogenic (VEGFR1-3, TIE2), stromal (PDGFR- β, FGFR), and oncogenic kinases (KIT, RET, RAF). In in vivo models, including NSCLC, regorafenib has demonstrated broad spectrum antitumor activity. administration (21 days (d) on/7 d off dosing) resulted 31% partial response (PR) rate Phase II study patients (pts) with metastatic renal cell cancer. Methods: This phase I assessed the safety, pharmacokinetics (PK),...

Minimally invasive surgery is becoming popular for treating spinal disorders. The advantages of percutaneous endoscopic debridement and drainage (PEDD) infectious spondylitis include direct observation the lesion, pus drainage, earlier pain relief. We retrospectively reviewed 37 patients who underwent PEDD 31 traditional anterior open interbody fusion with bone grafting from 2004 to 2012. causative organisms were isolated 30 (81.1%) following PEDD, 25 (80.6%) (p = 0.48). Staphylococcus...

Introduction: Fat embolism syndrome (FES) is a rare life-threatening condition that can develop after traumatic orthopedic injuries.Controversy remains concerning the epidemiology in elderly population.Therefore, this study aims to report FES related inhospital mortality stratified by age.Methods: A retrospective trauma cohort was conducted using data from National Trauma Data Bank (NTDB) 2007 2014.All cases were included with diagnosis of (ICD9 958.1).Death on arrival excluded.Patients age...

Abstract: Psoriasis of the nail greatly affects quality life because difficulty in achieving long‐lasting remission. Pustular psoriasis apparatus is characterized by formation sterile pustules, starting on one or two fingers less often toes, and spontaneous improvement has rarely been observed. This case presents a girl with refractory accompanied periodic pustular eruption that responded well to topical treatment indigo naturalis oil extract drops, remission longer than 1 year.

To compare the outcomes after surgical intervention, including external fixation (EF) with optional addition of K-pins or open reduction and internal (ORIF) a volar locking plate (VLP), in patients distal radius fracture aged > 80 years.We reviewed 69 years who treated under intervention from 2011 to 2017 retrospectively. Their demographic data complications were recorded. Preoperative, postoperative, last follow-up plain films analyzed. The functional wrist range motion also evaluated.41 EF...

In this study, polylactic acid (PLA) disks with antibacterial performances were prepared using 3D printing technology combined direct adsorption of the antibiotic agents in solution baths. The effects layer thicknesses for building PLA and amounts absorbed onto sample surfaces on their activities investigated. agent release profiles from samples surface into buffer show that these can reach up to 28 days. With a decrease concentration bath, amount adsorbed also decreases, but still maintain...

Upper lumbar herniated intervertebral disc (HIVD), defined as L1-2 and L2-3 levels, presents with a lower incidence more unfavorable surgical outcomes than levels. There are very few reports onthe appropriate interventions for treating upper HIVD. This study aimed to evaluate the outcome of decompression alone, when compared spinal fusion surgery. A retrospective involving total 7592 patients who underwent surgery due HIVD in our institution was conducted. 49 were included this study: 33...

Guided growth using titanium tension band plates is an advancement in the correction of angular deformity. We applied two-hole stainless-steel one-third tubular for same purpose. There were 14 deformities around knees eight children, mean age 10.8 years at operation. The success rate was 92.9% (13/14). average per month 0.59° femur and 0.65° tibia. No premature physeal arrest, overcorrection, or rebound phenomenon observed. A plate a safe effective option guided surgery countries where only...