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Ryan T. Fansler

ORCID: 0000-0002-5432-8082
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About
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A5074205478
Research Areas
  • Lipid Membrane Structure and Behavior
  • Bacterial Genetics and Biotechnology
  • Bacterial biofilms and quorum sensing
  • Clostridium difficile and Clostridium perfringens research
  • Diet and metabolism studies
  • Helicobacter pylori-related gastroenterology studies
  • Galectins and Cancer Biology
  • Gut microbiota and health

Vanderbilt University Medical Center
 2023

Vanderbilt University
 2022

 Iron acquisition by a commensal bacterium modifies host nutritional immunity during Salmonella infection
OPENALEX - Publications 
Luisella Spiga Ryan T. Fansler Y. Randika Perera Nicolas G. Shealy Matthew J. Munneke and 13 more Holly E. David Teresa P. Torres Andrew Lemoff Xinchun Ran Katrina Richardson Nicholas A. Pudlo Eric C. Martens Ewa Folta‐Stogniew Zhongyue Yang Eric P. Skaar Mariana X. Byndloss Walter Chazin Wenhan Zhu

10.1016/j.chom.2023.08.018 article EN publisher-specific-oa Cell Host & Microbe 2023-09-29
 Iron acquisition by a commensal bacterium modifies host nutritional immunity duringSalmonellainfection
OPENALEX - Publications 
Luisella Spiga Ryan T. Fansler Y. Randika Perera Nicolas G. Shealy Matthew J. Munneke and 12 more Teresa P. Torres Holly E. David Andrew Lemoff Xinchun Ran Katrina Richardson Nicholas A. Pudlo Eric C. Martens Zhongyue Yang Eric P. Skaar Mariana X. Byndloss Walter Chazin Wenhan Zhu

Abstract During intestinal inflammation, host nutritional immunity starves microbes of essential micronutrients such as iron. Pathogens scavenge iron using siderophores, which is counteracted by the lipocalin-2, a protein that sequesters iron-laden including enterobactin. Although and pathogens compete for in presence gut commensal bacteria, roles commensals involving remain unexplored. Here, we report Bacteroides thetaiotaomicron acquires inflamed utilizing siderophores produced other...

10.1101/2023.06.25.546471 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2023-06-26
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