Pavithra Mahadevan

ORCID: 0000-0002-5459-5551
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About
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Research Areas
  • Enzyme Structure and Function
  • Microbial Metabolic Engineering and Bioproduction
  • Biofuel production and bioconversion

Max Planck Institute for Medical Research
2023

The genomes of anaerobic ammonium-oxidizing (anammox) bacteria contain a gene cluster comprising genes unusual fatty acid biosynthesis enzymes that were suggested to be involved in the synthesis unique "ladderane" lipids produced by these organisms. This encodes an acyl carrier protein (denoted as "amxACP") and variant FabZ, ACP-3-hydroxyacyl dehydratase. In this study, we characterize enzyme, which call anammox-specific FabZ ("amxFabZ"), investigate unresolved biosynthetic pathway ladderane...

10.1016/j.jbc.2023.104602 article EN cc-by-nc-nd Journal of Biological Chemistry 2023-03-11
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