A5047526477- Peptidase Inhibition and Analysis
- vaccines and immunoinformatics approaches
- Antifungal resistance and susceptibility
University of Bahri
2020-2021
Candida glabrata is a human opportunistic pathogen that can cause life-threatening systemic infections. Although there are multiple effective vaccines against fungal infections and some of these engaged in different stages clinical trials, none them have yet been approved by the FDA.Using immunoinformatics approach to predict most conserved immunogenic B- T-cell epitopes from fructose bisphosphate aldolase (Fba1) protein C. glabrata. Material Method. 13 sequences (361 amino acids) were...
Abstract Background Candida glabrata is a human opportunistic pathogen that can cause life-threatening systemic infections. Although, there are multiple effective vaccines against fungal infections, and some of these were engaged in different stages clinical trials, none them yet approved by (FDA). Aim To predict the most conserved immunogenic B- T-cell epitopes from Fructose Bisphosphate aldolase (Fba1) protein C. . Materials Methods 13 bisphosphate sequences (361amino acid) retrieved NCBI...