Background and Objectives: Erdosteine (Erd) is an antioxidant anti-inflammatory drug. Vitamin B has been reported to exert effects. In this study, we investigated the effect of erdosteine vitamin complex on a liver ischemia/reperfusion (I/R) model. Materials Methods: Thirty-two Wistar Albino male rats weighing 350–400 g were used. The animals randomly selected divided into four groups. groups are as follows: first group (Sham), second (I/R), third (I/R + vit B), fourth Erd). Rats subjected...

The aim was to evaluate the effect of yellow and red centaury St. John's Wort (St. JW) oil on inflammation urethral fibrosis development in a rat trauma model. A total 24 male rats were divided into 5 groups. No damage induced sham group. urethras all other groups traumatized at 6 o'clock with specially designed urethrotome blade. Group 1 administered 0.5 cc JW once daily for 15 days. 2 intraurethrally 3 not treated administered). Sham group (Group 4), 5). 20-G/32-mm intravenous cannula...

Background This study explores the disparity in ER, PR, HER-2, and Ki-67 status between primary breast tumors (PBT) axillary lymph node metastasis (ALNM) at initial admission patients undergoing neoadjuvant chemotherapy (NAC).

<b><i>Objective:</i></b> Polycystic ovary syndrome (PCOS) is a serious endocrine disorder. In the present study, we investigated therapeutic effects of erdosteine in letrozole-induced PCOS rats. <b><i>Methods:</i></b> Thirty-two Wistar albino female rats were grouped as control group (C), (PCOS), PCOS-metformin (PCOS+MET), and PCOS-erdosteine (PCOS+Erd). was induced by administering letrozole; such presented with sex hormone disorder, abnormal...

We aimed to investigate the levels of transient receptor potential melastatin (TRPM) gene expression, and antioxidant histopathologic effect thymoquinone (Tmq) in hepatic I/R rat model.

Objectives: To evaluate the agreement among radiologists in evaluation of rectal cancer staging and restaging (after neoadjuvant therapy) assess whether locoregional recurrence can be predicted with this information. Materials Methods: Pre-neoadjuvant after-neoadjuvant therapy magnetic resonance imaging (MRI) examinations 239 patients diagnosed locally advanced were retrospectively reviewed by three radiologists. The between MRI findings (localization tumor involvement, coverage pattern,...

Leiomyoma is a type of benign smooth muscle neoplasm that common the uterus and gastrointestinal tract but rarely affects head neck region especially unlikely to affect oral cavity. The diagnosis leiomyoma mainly determined by histopathological studies due variation in its clinical appearance symptoms. In present paper we report two rare cases gingival angioleiomyoma posterior maxilla mandible. After total excision, hematoxylin-eosin actin staining confirmed angioleimyoma.

The aim of this study was to investigate the efficacy post-neoadjuvant chemotherapy (NAC) ultrasound (US), magnetic resonance imaging (MRI), and F-18fluorodeoxyglucose positron emission tomography (F-18 FDG-PET/CT) for detecting post-NAC axillary lymph node(ALN) metastasis in patients who had ALN at time diagnosis.This included all breast cancer received NAC metastasis; underwent assessment with US, MRI, or F18FDG-PET/CT; then were operated on General Surgery Clinic, Adana City Research...

Background and Aims The complete pathological response (pCR) following neoadjuvant chemotherapy (NAC) in breast cancer is essential for the accurate prediction of prognosis. We aimed to evaluate efficacy presence type peritumoral edema detected by magnetic resonance imaging (MRI) predicting pCR NAC patients. Methods Results One hundred five patients with diagnosis invasive carcinoma were evaluated MRI before NAC. Edema was fat-suppressed T2-weighted images. categorized into three groups: no...

The present study aims to evaluate whether perfusion parameters in prostate magnetic resonance imaging (MRI), (68)Ga-prostate-specific membrane antigen (PSMA) positron emission tomography (PET)/computed (CT), prostate-specific (PSA), and PSA density can be used predict the lesion grade patients with cancer (PCa).The included a total of 137 PCa cases which 12-quadrant transrectal ultrasound-guided biopsy (TRUSBx) was performed, Gleason score (GS) determined, pre-biopsy multiparametric MRI...

Aim: To investigate baseline enhanced chest CT findings that may predict progression or response to neoadjuvant chemoradiotherapy.
 Materials and methods: Multiple parameters be obtained from scans of 140 patients with NSCLC who had before chemoradiotherapy were noted. In addition features tumour tissues, age, gender, cell types, lymph node TNM stages, distant metastases on CT, bronchial vascular invasion also evaluated. Chest changes in tissue at 3 6 months during treatment Patients...

Abstract Objectives To evaluate the interobserver agreement and diagnostic accuracy of ovarian-adnexal reporting data system magnetic resonance imaging (O-RADS MRI) applicability to machine learning. Methods Dynamic contrast-enhanced pelvic MRI examinations 471 lesions were retrospectively analysed assessed by 3 radiologists according O-RADS criteria. Radiomic extracted from T2 post-contrast fat-suppressed T1-weighted images. Using these data, an artificial neural network (ANN), support...

To determine the effectiveness of Milan system for evaluation aspiration cytology to salivary gland lesions classification.Cross-sectional observational study.Department Pathology, Tertier Centre, University Health Sciences, Adana City Education and Research Hospital, Adana, Turkey from January 2014 December 2020.Salivary last six years was recategorised, according classification. Risk malignancy (ROM) risk neoplasm (RON) were determined among subgroups in cytological materials 233 patients,...

Phyllodes tumours are uncommon breast neoplasms constituting 1-2% of malignancies.Metastasis is usually haematogenous, and axillary lymph node dissection not routinely performed.A phyllodes tumour with concomitant invasive ductal carcinoma (IDC) even rarer.When IDCor in-situ (DCIS) detected, the management condition changes completely.We report a case 22-year female presenting mass in right palpable nodes.The pathological examination demonstrated malignant IDC DCIS.The patient elected to...

Background: Osteonecrosis (ON) is a serious health problem, which dramatically reduces the quality of life. Objectives: In present study on rat model glucocorticoids (GCs) -induced ON, we explored influence alpha-lipoic acid serum levels TGF-β1 and urotensin-II (U-II) histological alteration with respect to fatty degeneration osteocyte necrosis. Methods: A total 32 male Wistar albino rats were equally assigned four groups, including control, methylprednisolone acetate (MPA), (ALA), MPA ALA...

The most common cause of neurological symptoms in patients with systemic malignant tumors is central nervous system (CNS) metastases, and CNS metastases are one the important causes morbidity mortality these patients. metastatic to lung, breast, melanoma, genitourinary, gastrointestinal tumors. We aimed analyze our data on department, which belongs a large archive field neuropathology. who had between January 2015 August 2021 department were reviewed retrospectively. grouped terms...

Objective: To evaluate breast cancer patients with low F18-fluorodeoxy-glucose positron emission tomography/computed tomography scan (FPET) of axilla standardised maximum uptake value (SUVmax) along their histopathological findings regarding axillary lymph node metastasis (LNM).Study Design: A descriptive study.

Background: In our study, thyroid fine-needle aspiration biopsy (FNAB) data in the same calendar period of 1 year before and after COVID-19 pandemic were compared.Methods: Thyroid FNAB for included study. The patients grouped according to age, gender FNABs Bethesda system reporting cytopathology, both groups compared considering diagnoses who underwent surgery afterwards.Results: post-pandemic period, number over age 40 decreased (all p<0.001). rates atypia undetermined significance or...