- Ancient Egypt and Archaeology
- Archaeology and Historical Studies
- Advanced Battery Materials and Technologies
- Conducting polymers and applications
- Functional Brain Connectivity Studies
- EEG and Brain-Computer Interfaces
- Synthetic Organic Chemistry Methods
- Neural dynamics and brain function
- Dielectric materials and actuators
- Advanced Neuroimaging Techniques and Applications
- Organometallic Complex Synthesis and Catalysis
- Archaeological Research and Protection
- Biblical Studies and Interpretation
- Ancient Mediterranean Archaeology and History
- Ginkgo biloba and Cashew Applications
- Cancer, Hypoxia, and Metabolism
- Ancient Near East History
- Plant biochemistry and biosynthesis
- Advanced MRI Techniques and Applications
- Radiopharmaceutical Chemistry and Applications
- Transgenic Plants and Applications
- Infrared Thermography in Medicine
- Analytical Chemistry and Sensors
- Covalent Organic Framework Applications
- Lipid Membrane Structure and Behavior
University of Otago
2020-2025
Toronto Metropolitan University
2017-2023
California Institute of Technology
2007-2014
Monmouth University
2013
Lamont-Doherty Earth Observatory
2007
Columbia University
2005-2007
California NanoSystems Institute
2007
University of California, Los Angeles
2007
National Institutes of Health
2004
National Heart Lung and Blood Institute
2004
Plasma membrane proteins that are internalized independently of clathrin, such as major histocompatibility complex class I (MHCI), in vesicles fuse with the early endosomes containing clathrin-derived cargo. From there, MHCI is either transported to late endosome for degradation or recycled back plasma via tubular structures lack clathrin-dependent recycling cargo, e.g., transferrin. Here, we show small GTPase Rab22a associated these intermediates MHCI. Expression a dominant negative mutant...
A strategy for the formation of mechanically interlocked polymers is presented. Ring-closing olefin metathesis has been shown to provide a very high yielding route [c2]daisy-chains suitably functionalized allow their one-step conversion bisolefins which can be used as monomers in ADMET polymerizations afford polymers. Metathesis, two different guises making hitherto unreachable goal synthesis reality.
Capturing individual differences in cognition is central to human neuroscience. Yet our ability estimate cognitive abilities via brain MRI still poor both prediction and reliability. Our study tested if this inability can be improved by integrating signals across the whole modalities, including task-based functional (tfMRI) of different tasks along with other non-task such as structural MRI, resting-state connectivity. Using Human Connectome Project (n = 873, 473 females, after quality...
Diagnosing pain in research and clinical practices still relies on self-report. This study aims to develop an automatic approach that works resting-state raw EEG data for chronic knee prediction. A new feature selection algorithm called "modified Sequential Floating Forward Selection" (mSFFS) is proposed. The improved scheme can better avoid local minima andexplore alternative search routes. obtained by mSFFS displays class separability as indicated the Bhattacharyya distance measures...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHighly conductive solid polymer electrolytes prepared by blending high molecular weight poly(ethylene oxide), poly(2- or 4-vinylpyridine), and lithium perchlorateJean Li Ishrat M. KhanCite this: Macromolecules 1993, 26, 17, 4544–4550Publication Date (Print):August 1, 1993Publication History Published online1 May 2002Published inissue 1 August 1993https://pubs.acs.org/doi/10.1021/ma00069a020https://doi.org/10.1021/ma00069a020research-articleACS...
The objective of this study was to develop an acylation agent for the radioiodination monoclonal antibodies that would maximize retention label in tumor cells following receptor- or antigen-mediated internalization. strategy taken add a polar substituent labeled aromatic ring impede transport catabolites across lysosomal and cell membranes after antibody degradation. Preparation unlabeled N-succinimidyl 4-guanidinomethyl-3-iodobenzoate (SGMIB) achieved six steps from 3-iodo-4-methylbenzoic...
New procedures for the synthesis of N-heterocyclic carbenes with multiple fused rings have been developed utilizing a key ring-closing metathesis step. Rhodium complexes were obtained via pentafluorophenyl carbene adducts. Solid-state structural behaviors new ligands analyzed X-ray crystallography.
Abstract Poly(2,5,8,11,14,17,20,23‐octaoxapentacosyl methacrylate)‐ block ‐poly(4‐vinylpyridine) semicomb polymers were synthesized using anionic living polymerization techniques. The are white, powdery materials and characterized by 1 H 13 C nuclear magnetic resonance spectroscopy gel‐permeation chromatography. display monomodal molecular weight distributions which relatively narrow. copolymers show microphase separation as indicated the presence of two glass transition temperatures ( T g...
We report the first kinetic resolution by ring-opening metathesis polymerization (KR-ROMP). The profile showed a solvent-dependent variation of selectivity (S) over course reaction. In tetrahydrofuran and dichloromethane, increased reaction, while in toluene was much higher beginning reaction decreased throughout. Evidence suggests that change might be attributed to chiral secondary structure growing polymer chain.
Abstract Poly(ethylene oxide) (MW 600,000)/poly(2vinylpyridine) 200,000)/LiClO 4 blends have been prepared by the solution blending process. The ionic conductivities of containing lower weight fractions (15, 17.5, 20 and 22.5%) poly (2vinylpyridine) initially increases as salt content is increased, reaches a maximum at an ethylene oxide/Li + mole ratio 10 decreases further increased. Blends, which higher poly(2vinylpyridine) (25 35%) display different electric behavior, i.e., conductivity...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPoly(ethylene oxide)/poly(2-vinylpyridine)/lithium perchlorate blends. New materials for solid polymer electrolytesJean Li, Eric A. Mintz, and Ishrat M. KhanCite this: Chem. Mater. 1992, 4, 6, 1131–1134Publication Date (Print):November 1, 1992Publication History Published online1 May 2002Published inissue 1 November 1992https://pubs.acs.org/doi/10.1021/cm00024a002https://doi.org/10.1021/cm00024a002research-articleACS PublicationsRequest reuse...
Effective analysis of EEG signals remains a challenging task. So far, the and conditioning have largely remained gender-neutral. This paper explores evidence gender effects on confirms generality these by achieving successful prediction through signals. Specifically, we propose novel statistical feature representation that captures discrepancy, design customized classification ensemble framework to overcome non-stationary characteristics in signals, utilizing findings obtained several...
Brain-wide association studies (BWASs) have attempted to relate cognitive abilities with brain phenotypes, but been challenged by issues such as predictability, test-retest reliability, and cross-cohort generalisability. To tackle these challenges, we proposed a machine-learning "stacking" approach that draws information from whole-brain magnetic resonance imaging (MRI) across different modalities, task-fMRI contrasts functional connectivity during tasks rest structural measures, into one...
Ginkgolides, the unique terpene trilactones from Ginkgo biloba tree, are believed to enhance memory, improve blood circulation and exhibit beneficial effects in treatment of dementia.Unfortunately, mechanisms ginkgolide actions at molecular level still not determined.Ginkgolide skeleton modifications may provide a plausible approach address subtle changes ligand-receptor interactions.Furthermore, simplified structure guide leads that will be attractive for drug development.This review covers...