Hongkun Ma

ORCID: 0000-0002-5668-3117
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About
Contact & Profiles
Research Areas
  • Advanced biosensing and bioanalysis techniques
  • Electrochemical sensors and biosensors
  • Biosensors and Analytical Detection
  • CRISPR and Genetic Engineering
  • Gout, Hyperuricemia, Uric Acid
  • Carbon and Quantum Dots Applications
  • Advanced Nanomaterials in Catalysis
  • RNA Interference and Gene Delivery
  • Alkaline Phosphatase Research Studies
  • Conducting polymers and applications
  • Robotic Mechanisms and Dynamics
  • Industrial Technology and Control Systems
  • Layered Double Hydroxides Synthesis and Applications
  • Gear and Bearing Dynamics Analysis
  • Hematological disorders and diagnostics
  • Covalent Organic Framework Applications
  • Pancreatitis Pathology and Treatment
  • Phase Change Materials Research
  • Analytical Chemistry and Sensors
  • Electrochemical Analysis and Applications
  • Crystallography and molecular interactions
  • Mechanical Engineering and Vibrations Research
  • Adsorption and Cooling Systems
  • SARS-CoV-2 detection and testing
  • Bacteriophages and microbial interactions

Mudanjiang Medical University
2022-2025

University of Birmingham
2023

Shanghai University of Medicine and Health Sciences
2022

Northeastern University
2021

Tarim University
2010-2012

Circulating tumor DNA (ctDNA) is a critical biomarker for early detection. However, accurately quantifying low-abundance ctDNA in human serum remains significant challenge. To address this challenge, we introduce bimodal biosensor tailored detecting the epidermal growth factor receptor (EGFR) mutation L858R specific nonsmall cell lung cancer (NSCLC) patients. This utilizes dual CRISPR-Cas12a systems to quantify target via fluorescence and electrochemical signals. In our system, EGFR exhibits...

10.1021/acs.analchem.4c03012 article EN Analytical Chemistry 2024-08-12

<title>Abstract</title> Objective Alkaline phosphatase (ALP) and calcium (Ca) levels are common indexes in serum biochemical tests, but their relationship with HUA hyperglycemia is still unclear. The objective of this study was to investigate the ALP Ca cold region China. Methods Baseline data were collected via questionnaires, blood samples analyzed biochemically. Spearman correlation multiple linear regression examined associations between ALP, Ca, uric acid (SUA), fasting glucose (FPG). A...

10.21203/rs.3.rs-5767770/v1 preprint EN cc-by Research Square (Research Square) 2025-01-13

Dopamine (DA) has been found as a significant neurotransmitter. Since abnormal concentrations of DA can induce series serious diseases. Simple, economical and efficient sensors should be developed to detect DA. In this study, highly selective electrochemical sensor was using nafion (NA) multi-walled carbon nanotubes- <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$\beta $ </tex-math></inline-formula>...

10.1109/jsen.2022.3149270 article EN IEEE Sensors Journal 2022-02-07

Kinematic accuracy is a crucial indicator for evaluating the performance of mechanisms. Low-mobility parallel mechanisms are examples robots that have been successfully employed in many industrial fields. Previous studies analyzing kinematic analysis typically ignore randomness each component input error, leading to imprecise conclusions. In this paper, we use homogeneous transforms develop inverse kinematics models an improved Delta mechanism. Based on and first-order Taylor approximation,...

10.3390/app11199002 article EN cc-by Applied Sciences 2021-09-27

Pseudomonas aeruginosa (P. aeruginosa) stands out as a prevalent pathogenic bacteria in nosocomial infections, often leading to severe conditions such bacteremia, sepsis, and potentially fatal outcomes. The protracted nature of clinical diagnostic proce-dures poses challenge promptly addressing infections. Therefore, the development swift precise detection methodologies is imperative. In this investigation, fluorescent nanomaterial IRMOF3 was incorporated into electrode by hybridization...

10.2139/ssrn.4713851 preprint EN 2024-01-01

Nuclear matrix protein 22 (NMP22) is one of the most important tumor markers bladder cancer and significantly elevated in urine patients.

10.1039/d4ay01066c article EN Analytical Methods 2024-01-01

10.1016/j.theochem.2009.12.022 article EN Journal of Molecular Structure THEOCHEM 2010-01-05
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