A5028821092- Drug Solubulity and Delivery Systems
- Advanced Drug Delivery Systems
- Analytical Methods in Pharmaceuticals
- Computational Drug Discovery Methods
- Surfactants and Colloidal Systems
- Biochemical Analysis and Sensing Techniques
- Protein purification and stability
Technical University of Denmark
2015
Novo Nordisk (Denmark)
2014-2015
University of Copenhagen
2014
Structural traits of permeation enhancers are important determinants their capacity to promote enhanced drug absorption. Therefore, in order obtain a better understanding structure–activity relationships for enhancers, Quantitative Activity Relationship (QSAR) model has been developed. The random forest-QSAR was based upon Caco-2 data 41 surfactant-like from Whitehead et al. (2008) and molecular descriptors calculated structure. QSAR validated by two test-sets: (i) an eleven compound...