A5002725189- Blood transfusion and management
- Blood groups and transfusion
- Hemoglobinopathies and Related Disorders
- Lymphoma Diagnosis and Treatment
- Erythrocyte Function and Pathophysiology
- Venous Thromboembolism Diagnosis and Management
- Erythropoietin and Anemia Treatment
- Immune Cell Function and Interaction
- Viral-associated cancers and disorders
- Platelet Disorders and Treatments
- Chronic Lymphocytic Leukemia Research
- Medieval Literature and History
- Blood Coagulation and Thrombosis Mechanisms
- Atrial Fibrillation Management and Outcomes
- Cytomegalovirus and herpesvirus research
- Glycosylation and Glycoproteins Research
- Complement system in diseases
- Hematopoietic Stem Cell Transplantation
- Cardiovascular and Diving-Related Complications
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Infectious Disease Case Reports and Treatments
- Galectins and Cancer Biology
- Liver Disease Diagnosis and Treatment
- Heparin-Induced Thrombocytopenia and Thrombosis
- Blood donation and transfusion practices
The University of Sydney
2013-2024
UNSW Sydney
2024
NHS Lothian
2014
Bridgewater State University
2010
Georgetown University
2008
University of Bologna
2006
Parks Victoria
2003
Rhode Island Hospital
1987-2001
Brown University
1990-2001
Boston Medical Center
1974-2001
Abstract Aims The 2019 report from the European Society of Cardiology (ESC) Atlas provides a contemporary analysis cardiovascular disease (CVD) statistics across 56 member countries, with particular emphasis on international inequalities in burden and healthcare delivery together estimates progress towards meeting 2025 World Health Organization (WHO) non-communicable targets. Methods results In this report, CVD are presented for countries ESC. drawn ESC which is repository data variety...
To study whether the administration of recombinant human erythropoietin increases amount autologous blood that can be collected before surgery, we conducted a randomized, controlled trial in 47 adults scheduled for elective orthopedic procedures. The patients received either (600 units per kilogram body weight) or placebo intravenously twice week 21 days, during which time up to 6 was collected. Patients were excluded from donation when their hematocrit values less than 34 percent. All iron...
To determine the extent to which autologous blood that has been donated in advance ("predeposited") is used patients undergoing elective surgery and assess whether predonation decreases use of homologous demand on supply, we studied 4996 at 18 tertiary care hospitals. Cross-matched was ordered for 1287 (26 percent), these, 590 (46 percent) were considered eligible predepositing blood. Only 5 percent (32) actually predeposited blood, indicating not widely used. Of those who predeposited, only...
BACKGROUND: Preoperative bleeding time (BT) does not correlate with postoperative in patients subjected to surgical procedures. A significant positive correlation has been reported between the BT 2 hours after cardiopulmonary bypass surgery and nonsurgical blood loss during first 4 surgery. This study was done investigate effect of Hct platelet count on measurement normal, healthy men women. STUDY DESIGN AND METHODS: To assess relative RBCs platelets BT, 22 male 7 female volunteers were...
Hodgkin's disease (HD) was diagnosed in 24 patients who were either seropositive for human immunodeficiency virus (HIV) (21) or members of a high-risk group (three), but had not developed acquired immune deficiency syndrome (AIDS). Clinical presentation the characterized by constitutional symptoms all, especially fever (23/24) and disseminated (22/24) at diagnosis. Mediastinal adenopathy rare. Bone marrow involvement particularly frequent (12/24), positive bone biopsy preceded lymph node 5...
Gastrointestinal involvement occurs in a greater proportion of patients with malignant lymphoma Waldeyer's ring than would be accounted for by chance alone. In the absence direct lymphatic connection between these two sites, association tumors has prompted several hypotheses: that gastrointestinal is concomitant primary tumor; or it related to swallowing and implantation tumor cells; represents homing tendency gut-associated lymphoid tissue. Five cases are described which developed ten...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTInhibition of human leukocyte elastase by derivatives N-hydroxysuccinimide. A structure-activity-relationship studyW. C. Groutas, M. J. Brubaker, A. Stanga, Castrisos, P. Crowley, and E. SchatzCite this: Med. Chem. 1989, 32, 7, 1607–1611Publication Date (Print):July 1, 1989Publication History Published online1 May 2002Published inissue 1 July 1989https://pubs.acs.org/doi/10.1021/jm00127a034https://doi.org/10.1021/jm00127a034research-articleACS...
Abstract Techniques are presented which result in the production of thromboresistant materials can be used to interface with blood vascular system. Three useful processes for heparinization and data given on characteristics attachment, compatibility, environmental stability these surfaces. At this point, applications heparinized surfaces via a simple one‐step process should limited siturations where low shear rates involved, such as venous Intitial indicate significant loss surface heparin...
Leukocytes were removed from washed, freeze‐preserved red blood cells primarily by the clumping together of damaged cells. This agglomeration was associated with membrane and nuclear changes which usually manifested after removal glycerol Washing glycerolized, leukocytes solutions containing deoxyribonuclease prevented agglomeration. Polymorphonuclear granulocytes preferentially removed. Of residual that isolated dextran sedimentation method, 70 per cent lymphocytes. The dye exclusion test...
We studied the prevalence of thalassemia trait in a group Italian male myocardial infarction (MI) patients and an ethnically similar men admitted for other conditions. constituted approximately 13% each group. Of 359 with MI, only 2 had trait. In contrast, 330 adult males non-MI (mean age 59.6 years), 11 Because frequency was significantly (p < 0.01) lower infarct group, we conclude that may be protective attribute as regards MI. A prospective study individuals minor is indicated to...
Abstract. Most of the leukocytes were removed from red cells during glycerolization, frozen storage at – 80 °C, and washing. Residual lymphocytes that isolated washed found to be responsive phytohemagglutinin stimulation. Since phytohemagglutinin‐responsive appear mediate graft‐versus‐host reaction, it is imperative freeze‐preserved handled with same precautions as other blood products before transfusion patients immunologic deficiencies.
In the study of 125 units washed, previously frozen red blood tells approximately 96.6 per cent leukocytes and 98.9 platelets were removed. Less than 0.5 mg plasma protein remained unit. The length storage as whole at 4 C prior to glycerolization cells influenced number in cells. Red on day collection had 7.2 residual white cells, whereas those stored for 10 days or longer glycerolization, freezing, washing 1.1 leukocytes. When one week, glycerolized, washed without they about 2 platelets....
Summary Reasons for performing study Oxidative stress ( OS ) is most simply defined as an imbalance between oxidants and antioxidants. has been suggested to play roles in various equine respiratory diseases the significance of pathogenesis R hodococcus equi pneumonia unknown. Objectives To measure relate biomarkers lesions consistent with R. pneumonia. Study design Case–control study. Methods Various were measured from blood exhaled breath condensate EBC samples collected 26 foals 1 2 months...
Documentation of overwhelming post-splenectomy sepsis, characterized by infection from encapsulated organisms, has led to development surgical techniques for preservation the injured spleen maintain splenic clearance encapsulated, opsonized organisms circulation. In this study artery ligation (SAL) was performed as an adjunct seccessful splenorrhaphy in 20 adults suffering blunt injury. There were no deaths and reoperations. Twenty units blood transfused ten patients. Splenic removal...
A patient with nephrotic syndrome due to membranous glomerulonephritis experienced painful bilateral renal vein thrombosis (RVT) complicated by pulmonary emboli. He was treated systemic fibrinolysis streptokinase for 72 hours. Rapid clinical improvement of his condition, a fall in serum creatinine level, and sharp rise platelet count were observed. Venography verified complete lysis the thrombus within vena cava reperfusion right vein. The left remained chronically occluded. Thrombolytic...
The authors observed a patient with severe inflammatory bowel disease (IBD) complicated by ten episodes of deep venous thrombosis (DVT). Her unusual thrombotic tendency prompted further investigation for primary hypercoagulability. A nonfamilial deficiency Protein S was documented suggesting the acquired. This occurrence suggests that low levels should be considered as potential etiologic factor in patients IBD and recurrent DVT.
Sclerosis was observed in the lymph node specimens of 26 57 (46%) patients with diffuse histiocytic lymphoma. Two major types sclerosis were observed: “compartmentalizing” (56%), which tumor divided into many small compartments by anastomosing, hyalinized stroma; and “diffuse” (44%), occurred without evident partitioning tumor. The stroma compartmentalizing frequently continuous vessels accompanied aggregates lymphocytes, suggesting that related to occurrence lymphocyte-associated...
The staining reaction of a panel lectins in paraffin embedded lymph node specimens diffuse large cell lymphoma was studied relation to survival. In 47 49 patients, varying degrees lectin binding were observed with Ricinus communis agglutinin (RCA), crude extract Arachis hypogaea (c-PNA), Concanavalin ensiformis A (Con A), Triticum vulgaris (WGA) and Phaseolus (PHA). Binding either absent or only minimal Pisum sativum (PSA) Lens culinaris (LCA). Two categories observed: surface cytoplasmic....