A5047190561- Genomic variations and chromosomal abnormalities
- Congenital heart defects research
- Cardiomyopathy and Myosin Studies
- Prenatal Screening and Diagnostics
- Reproductive Biology and Fertility
- Williams Syndrome Research
- Renal and related cancers
- Genomics and Chromatin Dynamics
- Chromosomal and Genetic Variations
City Hospital No. 40
2020
Research Institute of Obstetrics and Gynecology named after D.O. Ott
2015
St Petersburg University
2015
Since the very first publications on preimplantation genetic testing, researchers have faced a serious problem — high mosaicism level in human embryos obtained by means of vitro fertilization cycles. The nature this and its impact embryo development draws attention to issue. In research we studied cells from different parts with trophectoderm detected using Next-generation Sequencing (NGS). Six blastocysts their were each sectioned three parts: two containing only one predominantly inner...
Autosomal reciprocal translocations represent exchanges of chromatin fragments between non-homologous chromosomes. Translocations are facilitated by the creation quadrivalent structures during first meiotic division, which characterized length translocated and centric segments, asymmetry, presence terminal breakpoints, all may impact segregation mode. Here, we report a rare case multiple within single family. This includes evaluation in each spouses an analysis their chromosome patterns as...