A5020962392- Corneal surgery and disorders
- Glaucoma and retinal disorders
- Corneal Surgery and Treatments
- Ocular Surface and Contact Lens
- Ocular Infections and Treatments
- Breast Cancer Treatment Studies
- T-cell and B-cell Immunology
- Metabolism and Genetic Disorders
- Gastric Cancer Management and Outcomes
- Medical Malpractice and Liability Issues
- Colorectal Cancer Screening and Detection
- RNA and protein synthesis mechanisms
- Patient Safety and Medication Errors
- Healthcare Quality and Management
- Porphyrin Metabolism and Disorders
- Reconstructive Surgery and Microvascular Techniques
- Healthcare Systems and Technology
- Lymphatic System and Diseases
- Retinal Diseases and Treatments
- Immunotherapy and Immune Responses
- Bacteriophages and microbial interactions
- Connective tissue disorders research
- Cardiac Imaging and Diagnostics
- Ocular Diseases and Behçet’s Syndrome
- Ophthalmology and Visual Health Research
University of Edinburgh
2019-2021
Princess Alexandra Eye Pavilion
2015-2021
Western General Hospital
2021
Institute of Genetics and Cancer
2019
University of Balochistan
2017
Queen Margaret Hospital
2014
University of Birmingham
2009-2012
Good Hope Hospital
2012
New Cross Hospital
2012
Brittle cornea syndrome (BCS) is a rare recessive condition characterised by extreme thinning of the and sclera. BCS results from loss-of-function mutations in poorly understood genes ZNF469 or PRDM5. In order to determine function elucidate pathogenic mechanisms, we used genome editing recapitulate human mutation orthologous mouse gene Zfp469. Ophthalmic phenotyping showed that homozygous Zfp469 causes significant central peripheral corneal arising reduced stromal thickness. Expression key...
Purpose: To report a case of Candida albicans endophthalmitis with no identifiable predisposing risk factors. Case Report: A 57-year-old male presented 3-day history worsening floaters and reduced visual acuity. Fundoscopy optical coherence tomography showed presence fluffy white preretinal intraretinal infiltrates. With past medical or evidence immunosuppression but having travelled abroad suffered from diarrhoea, fungal aetiology was thought to be unlikely as result, treatment commenced...
Lymphoid tissue inducer cells (LTi) play an important role in the development of lymphoid embryos. Adult CD4(+)CD3(-) LTi-like present a similar phenotype and gene expression to their embryonic counterpart have roles CD4(+) T-cell memory recovery following viral infection. However, adult are heterogeneous populations factors that regulate survival accumulation within secondary organs remain unclear, particular whether T-zone stroma is involved. Here we report identification characterization...
Purpose: To audit and analyse the accuracy of current biometric formulae on refractive outcomes following cataract surgery in patients with axial length less than 22 mm. Methods: A total 84 eyes from <22 mm were identified consecutive undergoing retrospectively at a single university hospital. All subjects had biometry using IOLMaster (Carl Zeiss Meditec, Inc, Dublin, CA, USA) Sensar AR40 intraocular lens implant (Abbott Medical Optics, USA). One eye each patient was randomly selected for...
Abstract Brittle Cornea Syndrome (BCS) is a rare recessive condition characterised by extreme thinning of the cornea and sclera. BCS results from loss-of-function mutations in poorly understood genes ZNF469 or PRDM5 . In order to determine function elucidate pathogenic mechanisms, we used genome editing recapitulate human mutation orthologous mouse gene, Zfp469 Ophthalmic phenotyping showed that homozygous causes significant central peripheral corneal arising reduced stromal thickness....