A5107072540- Drug-Induced Hepatotoxicity and Protection
- Liver Disease and Transplantation
- Nanoparticle-Based Drug Delivery
- Ferroptosis and cancer prognosis
- Nanocluster Synthesis and Applications
- Peroxisome Proliferator-Activated Receptors
- MicroRNA in disease regulation
- RNA modifications and cancer
- Ginger and Zingiberaceae research
- Protein Tyrosine Phosphatases
- Electrospun Nanofibers in Biomedical Applications
- Liver physiology and pathology
- Autophagy in Disease and Therapy
- Liver Disease Diagnosis and Treatment
- Bladder and Urothelial Cancer Treatments
- Gold and Silver Nanoparticles Synthesis and Applications
- Cancer Immunotherapy and Biomarkers
Xuzhou Medical College
2015-2024
Second People’s Hospital of Huai’an
2018-2024
Nanjing University of Chinese Medicine
2021-2024
Xuzhou No.1 People's Hospital
2018
BackgroundYi-Qi-Jian-Pi Formula (YQJPF) is a herbal medicine that used to treat patients with liver failure. However, scientific evidence supporting the treatment of hepatic fibrosis YQJPF has not been forthcoming. The present study aimed determine mechanisms underlying anti-fibrotic effects in mouse models fibrosis.MethodsMice were randomly assigned control, model, silymarin (positive treated), and low-, medium- high-dose (7.5, 15, 30 g/kg, respectively) groups. Liver function, inflammatory...
ABSTRACT Purpose This study aims to evaluate the antitumor activity of neoadjuvant immunochemotherapy in patients with cervical metastatic squamous cell carcinoma unknown primary (CMSCCUP), providing a new idea for its treatment. Method We retrospectively examined medical records from Sun Yat‐sen University Cancer Center identify CMSCCUP July 2020 November 2023. CMSCCUP's diagnoses are based on results biopsy and imaging examination. All received PD‐1 inhibitors combined chemotherapy:...
Interaction between microRNA (miR-328) and PTPRJ (protein tyrosine phosphatase, receptor type, J) has been reported to be responsible for miR-328-dependent increase in epithelial cancer cell proliferation. However, the role of miR-328 hepatocellular carcinoma (HCC) remains unclear. The aim this study was investigate clinical significance and/or expression human HCC determine their precise biological functions malignancy.Expression levels messenger RNA (mRNA) 100 pairs adjacent noncancerous...
Background: Globally, hepatocellular carcinoma (HCC) is the sixth most frequent malignancy with a high incidence and poor prognosis. Immune cell infiltration (ICI) underlies both carcinogenesis immunogenicity of tumors. However, comprehensive classification system based on immune features for HCC remains unknown. Methods: The dataset from Cancer Genome Atlas (TCGA) International Consortium (ICGC) cohorts was used in this study. ICI patterns 571 patients were characterized using two...