- Advanced Chemical Sensor Technologies
- Gas Sensing Nanomaterials and Sensors
- Sarcoma Diagnosis and Treatment
- Telomeres, Telomerase, and Senescence
- Microtubule and mitosis dynamics
- Insect Pheromone Research and Control
- Mitochondrial Function and Pathology
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- RNA Research and Splicing
- Gastrointestinal Tumor Research and Treatment
- Cancer and Skin Lesions
- Air Quality Monitoring and Forecasting
- Thyroid Cancer Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Hepatocellular Carcinoma Treatment and Prognosis
- IgG4-Related and Inflammatory Diseases
- Musculoskeletal synovial abnormalities and treatments
- Virus-based gene therapy research
- Cancer-related molecular mechanisms research
- Testicular diseases and treatments
- Ear and Head Tumors
- Neuroblastoma Research and Treatments
- Breast Cancer Treatment Studies
Chongqing Cancer Hospital
2014-2025
Chongqing University
2021-2025
Guangxi University
2023-2025
Cancer Institute (WIA)
2022
Chongqing Medical University
2022
Longyan University
2021
Chengdu University of Technology
2015
Friedrich-Alexander-Universität Erlangen-Nürnberg
2001
To assess the advantages and disadvantages of a direct adenoviral cell-mediated approach to induction cartilage formation in joints by transfer growth factor genes.Adenoviral vectors carrying insulin-like 1 (IGF-1) or bone morphogenetic protein 2 (BMP-2) complementary DNA were constructed applied primary human murine chondrocytes fibroblasts. Transgene expression was quantified enzyme-linked immunosorbent assay. Direct injection these AdLacZ, reporter gene vector, into mouse knee compared...
Myoepithelioma-like tumor of the vulvar region (MELTVR) is a rare type soft tissue mesenchymal tumor. While MELTVR exhibits histological characteristics similar to myoepithelial tumors, its immunohistochemical and genetic features differ significantly. To date, no comprehensive genomic analysis this has been conducted. We present clinicopathological features, imaging characteristics, immunophenotypes three patients with MELTVR, along their characterization through high-throughput sequencing....
Vaginal paraganglioma is a rare and unusual tumor occurring in the vaginal wall. It solitary primary paraganglioma, especially atypical sites. Herein, we report an case of 17-year-old woman who had not experienced vomiting, or hypertension. She was found to have immobile solid mass right side her Positron emission tomography/computed tomography scans revealed well-defined ovoid adjacent bladder pelvic floor. Tumor markers were within normal range. A transient blood pressure increase occurred...
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Liver metastases (LM) are the most common tumors encountered in liver and continue to be a significant cause of morbidity mortality. Identification primary tumor any LM is crucial for implementation effective tailored treatment approaches, which still represents difficult problem clinical practice.The resection or biopsy specimens associated clinicopathologic data were archived from seven independent centers between January 2017 December 2020. The sites verified through evaluation available...
The heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1), telomeric repeat-containing RNA (TERRA), and protection of telomeres 1 (POT1) have been reported to orchestrate displace replication protein A (RPA) from overhangs, ensuring orderly telomere capping. Our previous studies further demonstrated that DNA-dependent kinase catalytic subunit (DNA-PKcs)-dependent hnRNPA1 phosphorylation plays a crucial role in the promotion binding overhangs RPA displacement during G2-M phases. However, it is...
In order to investigate the influence of different soil nailing parameters on safety factor a slope, slope stability is analyzed by GeoStudio software with analysis methods. Soil (such as nail inclination, horizontal space, diameter and length) that are Morgenstern-Price method. As results show, has highest when obliquity about 15°, decreases increase soil-nail space an evident acceptable range 2 m or less increases linearly length. However length equals approximately height slowly. These...
Abstract Angioimmunoblastic T‐cell lymphoma (AITL) is the subtype of mature non‐Hodgkin lymphoma. Compared with diffuse large B‐cell (DLBCL), AITL patients are frequently accompanied Epstein–Barr virus (EBV) infection. To date, there no report on subsequent development in EBV‐positive DLBCL. We performed a rare case developing one year after initial diagnosis The patient showed poor response to chemotherapy regimen, and survival.
Background: Immunogenic cell death (ICD) has emerged as a potential mechanism mediating adaptive immune response and tumor immunity in anti-cancer treatment. However, the signature of ICD high-grade gliomas (HGGs) remains largely unknown, its relevance to immunotherapies is still undetermined. The purpose this study identify ICD-associated genotypes order explore their immunity, patient prognosis therapeutic efficacy checkpoint blockade (ICB) therapy HGGs. Methods: Bulk RNA-seq data clinical...
The air has a direct impact on both life and health. In most situations, the damage caused by excessive inhalation of carbon monoxide (CO) is irreversible. order to prevent further catastrophes, these topics are more deserving our attention effective action. According available research, electronic nose (E-nose) consistently exhibits great performance in additional sectors while offering fresh approaches problem-solving. However, neural networks currently used E-nose still somewhat...
As one of the harmful substances in atmosphere, carbon monoxide (CO) is to human beings. With wide application gas sensors and machine learning algorithms, accuracy concentration predicting various such as CO constantly improving. Now we apply TrellisNet, a network utilizing both recurrent convolutional techniques, prediction, which also time-series prediction task, with aim improving its performance. To enhance TrellisNet’s ability retain long time series information, replaced activation...
Inflammatory myofibroblastic tumors (IMTs) are rare lesions with distinct clinical, pathological, and molecular characteristics. IMTs typically arise in the abdominal soft tissues, including mesentery, omentum, retroperitoneum, followed by lungs mediastinum, usually affect both children young adults. Herein, we present a case of an IMT submandibular gland 47-year-old male patient. Microscopically, tumor displayed infiltrative growth pattern diffuse glandular tissue destruction. Their...
Introduction: Alveolar soft part sarcoma (ASPS) is a rare and distinct subtype of tissue sarcoma. This study aims to describe the unique presentation ASPS in female genital tract. Methods: Prognostic factors for cancer-specific overall survival (CSS) were evaluated using multivariate analyses. Results: In our case series, we identified novel TFE3-PRCC gene fusion 24-year-old unmarried patient with cervical who underwent fertility-sparing surgery remained recurrence-free 41 months. The other...
Electronic nose (E-nose) is an important means for machines to sense odor signals, but it faces a serious problem that limits its development, namely, sensor drift. Drift refers the long time and irregular changes in response signal of gas same analyte, will bring performance degradation E-nose. To reduce effect drift, we proposed entropy minimization model based on adversarial network (EMAD) which reduced distribution difference between data with without drift through training. EMAD...
Primary hepatoid adenocarcinoma of the gallbladder is a relatively rare type extrahepatic adenocarcinoma. The genetic changes involved in this were unexplained so far. We reported case primary with Mab-21 domain containing 2 (MB21D2), polypeptide N-acetylgalactosaminyltransferase 12 (GALNT12), and AT-rich interaction (ARID2) mutations, which was confirmed after surgical resection pathologically.A 69-year-old female distention hypogastrium constipation received enema treatment, but...
Plexiform fibromyxoma (PF) of the stomach is a very rare mesenchymal tumor gastrointestinal tract. We report first case PF with 2 different growth patterns pathologically confirmed after surgical resection. The was characterized microscopically as infiltrative; it demonstrated diffuse into smooth muscle bundles muscularis propria and also multinodular plexiform within myxoid stroma. Immunohistochemical analysis revealed that cells were positive or weakly for actin, vimentin, H-caldesmon...
Objective: To investigate the clinicopathologic features, differential diagnosis, immunohistochemical profiles and molecular characteristics of primary extraskeletal osteosarcoma (ESOS). Methods: Ten cases ESOS diagnosed treated in Fujian Provincial Hospital, Fuzhou, China from January 2003 to 2019 were collected subjected staining analyses. The patients followed up by telephone interview. Relative literature was also reviewed assess this tumor. Results: ten occurred 3 women 7 men, aged 36...
Supplementary Figure from Protein Phosphatase 2A–Dependent Mitotic hnRNPA1 Dephosphorylation and TERRA Formation Facilitate Telomere Capping
Supplementary Figure from Protein Phosphatase 2A–Dependent Mitotic hnRNPA1 Dephosphorylation and TERRA Formation Facilitate Telomere Capping
Accurate and real-time prediction of gas concentrations is a critical component intelligent systems holds significant importance for production safety quality life. However, due to the constraints network topology in sensor networks temporal nature concentration variations, has always been considered challenge. To simultaneously capture spatiotemporal correlations data with characteristics, this study proposes fully-connected multilayer graph convolutional (FTM-GCN). This method combines...