Elizabeth Le

ORCID: 0000-0002-5783-7034
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About
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Research Areas
  • Spinal Fractures and Fixation Techniques
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Acute Ischemic Stroke Management
  • Cervical and Thoracic Myelopathy
  • Spinal Cord Injury Research
  • Intracranial Aneurysms: Treatment and Complications
  • Cerebrovascular and Carotid Artery Diseases
  • Stroke Rehabilitation and Recovery
  • Spinal Hematomas and Complications
  • Vascular Malformations Diagnosis and Treatment
  • Case Reports on Hematomas
  • Venous Thromboembolism Diagnosis and Management
  • Peripheral Artery Disease Management
  • History of Medical Practice
  • Ultrasound and Hyperthermia Applications
  • Spinal Dysraphism and Malformations
  • Cerebrospinal fluid and hydrocephalus
  • Medical Imaging and Analysis
  • Cardiac Imaging and Diagnostics

University of Maryland, Baltimore
2016-2020

University of Maryland Medical Center
2016-2019

American Association of Neurological Surgeons
2016

University of Maryland Medical System
2016

Abstract BACKGROUND: Evidence indicates that, over time, patients with spinal cord injury (SCI) improve neurologically in various degrees. We sought to further investigate indicators of grade conversion cervical SCI. OBJECTIVE: To detect predictors ASIA impairment scale (AIS) SCI following surgical decompression. METHODS: In a retrospective study, demographics, clinical, imaging, and data from 100 consecutive were assessed for AIS conversion. RESULTS: American Spinal Injury Association motor...

10.1093/neuros/nyw053 article EN Neurosurgery 2016-12-27

Although decompressive surgery following traumatic spinal cord injury (TSCI) is recommended, adequate surgical decompression rarely verified via imaging. We utilized magnetic resonance imaging (MRI) to analyze the rate of after surgery. Pre-operative (within 8 h injury) and post-operative 48 MRI images 184 motor complete patients (American Spinal Injury Association Impairment Scale [AIS] grade A = 119, AIS B 65) were reviewed verify decompression. Decompression was defined as presence a...

10.1089/neu.2018.5834 article EN cc-by Journal of Neurotrauma 2018-09-14

In cervical traumatic spinal cord injury (TSCI), the therapeutic effect of timing surgery on neurological recovery remains uncertain. Additionally, relationship between extent decompression, imaging biomarker evidence severity, and outcome is incompletely understood. We investigated decompression long-term in patients with complete confirmed postoperative magnetic resonance (MRI). American Spinal Injury Association (ASIA) Impairment Scale (AIS) grade conversion was determined 72 AIS grades...

10.1089/neu.2019.6606 article EN cc-by Journal of Neurotrauma 2019-07-16

Background The first pass effect has been recently reported as a predictor of good clinical outcome after stroke thrombectomy. We evaluate the on and influence revascularization in these other patients. Methods performed retrospective analysis prospectively maintained database anterior cerebral circulation thrombectomy cases from April 2012 to 2018. Data compiled included patient demographics, presenting National Institutes Health Stroke Scale score, vessel occlusion site, procedural...

10.1136/neurintsurg-2019-014773 article EN Journal of NeuroInterventional Surgery 2019-05-02

OBJECT Studies of preclinical spinal cord injury (SCI) in rodents indicate that expansion intramedullary lesions (IMLs) seen on MR images may be amenable to neuroprotection. In patients with subaxial SCI and motor-complete American Spinal Injury Association (ASIA) Impairment Scale (AIS) Grade A or B, IML has been shown approximately 900 μm/hour. this study, the authors investigated a cohort AIS A, C, D. METHODS Seventy-eight who had at least 2 MRI scans within 6 days were enrolled. Data...

10.3171/2014.10.spine14576 article EN Journal of Neurosurgery Spine 2015-03-06

Background Flow diversion with the Pipeline embolization device is a well-established method of intracranial aneurysm treatment. However, deployment first-generation (Pipeline Classic) can be technically challenging. The Flex contains same flow-diverting stent modified delivery system. Objective To compare procedural outcomes between and Flex. Methods Thirty-eight first 40 consecutive patients who underwent treatment 58 most recent 60 Classic at our institution were evaluated. Patient...

10.1136/neurintsurg-2016-012261 article EN Journal of NeuroInterventional Surgery 2016-03-09

New device technology has changed the techniques used for revascularization of emergent large vessel occlusion in acute stroke. We report technical results using stent retrievers (SRs) thrombectomy alone versus SRs conjunction with a new group devices, intracranial aspiration catheters (IACs). Our aim is to demonstrate differences procedural time and attempts between these two groups.A retrospective evaluation was performed prospectively maintained database 97 patients treated at single...

10.1136/neurintsurg-2016-012581 article EN Journal of NeuroInterventional Surgery 2016-09-01

Objective Flow diversion using the Pipeline embolization device (PED) has become a widely used treatment method for intracranial aneurysms. However, subset of aneurysms will fail to occlude following and factors that influence efficacy flow remain uncertain. As smaller diameter PEDs inherently have greater metal density than larger devices, we elected investigate whether PED influences when single device. We also evaluated other may outcomes with PED. Methods retrospectively all patients...

10.1136/neurintsurg-2019-014792 article EN Journal of NeuroInterventional Surgery 2019-03-29

Aneurysmal subarachnoid hemorrhage (aSAH) is associated with significant morbidity and mortality. The presence of thick, diffuse blood may portend a worse clinical course outcome, independently other known prognostic factors such as age, aneurysm size, initial grade.

10.3171/2020.3.jns193400 article EN Journal of neurosurgery 2020-05-22

Study Design. A retrospective review (2001–2014) was conducted using prospectively collected data at a level I trauma center. Objective. We sought to determine the incidence and characteristics of complications occurring secondary therapeutic anticoagulation in adult spine patients. Summary Background Data. Numerous studies have assessed prophylactic after surgery, but none has investigated risks doses for treatment postoperative thromboembolic events. Methods. Patients were included if they...

10.1097/brs.0000000000002513 article EN Spine 2017-12-05

Although covered side branches typically remain patent acutely following Pipeline Embolization Device embolization of intracranial aneurysms, the long-term fate these vessels remains uncertain. We therefore elected to investigate factors that may influence patency branches.We retrospectively evaluated by at our institution during treatment aneurysms with least 6 months conventional angiography follow-up. Procedural and anatomic might were explored.One hundred forty-eight treatments in 137...

10.3174/ajnr.a5863 article EN cc-by American Journal of Neuroradiology 2018-11-01

Introduction The Sofia 6-French PLUS catheter is a recently approved aspiration for use in neuro-endovascular procedures. description of acute ischemic stroke limited. Objective purpose this article to describe our initial experience with the new treatment and report on its safety efficacy. Methods We performed retrospective study 54 thrombectomy cases treated catheter. Mean patient age admission National Institutes Health Stroke Scale score were 65.30 (1.92) 15.98 (0.89), respectively. most...

10.1177/1971400919887477 article EN The Neuroradiology Journal 2019-11-13

<h3>BACKGROUND AND PURPOSE:</h3> Previous studies in acute ischemic stroke have demonstrated the importance of minimizing delays to endovascular treatment and keeping thrombectomy procedural times at &lt;30–60 minutes. The purpose this study was investigate impact on clinical outcomes. <h3>MATERIALS METHODS:</h3> We retrospectively compared 319 patients having undergone according time (&lt;30 minutes, 30–60 &gt;60 minutes) from onset therapy (≤6 or &gt;6 hours). Clinical characteristics with...

10.3174/ajnr.a6556 article EN cc-by American Journal of Neuroradiology 2020-05-01

INTRODUCTION: Evidence presented by the Surgical Timing of Acute Spinal Cord Injury Study (STASCIS) was in favor early (within 24 hours) spinal cord decompression aimed at improved outcome. The exact definition and most favorable surgical technique suitable to offer circumferential release subarachnoid space around a swollen across several motion segments is, however, unknown. We compared pre- postoperative computed tomography (CT) magnetic resonance imaging (MRI) images crossed them against...

10.1227/01.neu.0000452380.95210.4a article EN Neurosurgery 2014-07-18

Introduction Experimental spinal cord injury and clinical studies indicate a relationship between MRI lesion length outcome. In patients with AIS grades A-B, IMLL expands at rate of 900 µm/hour, culminating in an intramedullary (IML) which measures ~50 mm 3 days post-injury. We performed retrospective analysis to measure the effect IML on long-term neurological recovery determine significance (IMLL) grade conversion traumatic cervical spine (TCSI). Methods Ninety-five adult who underwent...

10.1055/s-0036-1582936 article EN cc-by-nc-nd Global Spine Journal 2016-04-01

Background: Previous studies have demonstrated the importance keeping thrombectomy procedure times ≤60 min., termed ‘golden hour’. In current study, we further investigate significance of hour’ and impact procedural timing on clinical outcomes after mechanical thrombectomy. Methods: We performed an analysis 319 consecutive patients at a single Comprehensive Stroke Center from April 2012 through February 2019. Bivariate analyses compared grouped according to time min. or &gt;60 stroke...

10.1161/str.51.suppl_1.tp50 article EN Stroke 2020-02-01
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