A5017722060- Animal Virus Infections Studies
- Neurobiology and Insect Physiology Research
- Virus-based gene therapy research
- Insect and Pesticide Research
- Insect Resistance and Genetics
- Monoclonal and Polyclonal Antibodies Research
- Plant Taxonomy and Phylogenetics
- NF-κB Signaling Pathways
- Adsorption and biosorption for pollutant removal
- MicroRNA in disease regulation
- Genetic Mapping and Diversity in Plants and Animals
- Forest, Soil, and Plant Ecology in China
- Environmental and Agricultural Sciences
- Soil Mechanics and Vehicle Dynamics
- Rice Cultivation and Yield Improvement
- Plant Parasitism and Resistance
- Advanced X-ray and CT Imaging
- Plant and Fungal Species Descriptions
- Fungal Biology and Applications
- Aquaculture disease management and microbiota
- Water Quality Monitoring Technologies
- Viral Infectious Diseases and Gene Expression in Insects
- Bacteriophages and microbial interactions
- Advanced X-ray Imaging Techniques
- Pesticide Residue Analysis and Safety
Hunan Academy of Agricultural Sciences
2018-2025
Ministry of Agriculture and Rural Affairs
2024-2025
Institute of Plant Protection
2007-2025
Shanghai Pesticide Research Institute
2024-2025
Hubei Engineering University
2022-2024
Xiangnan University
2024
Wuhan Institute of Technology
2022-2023
Henan Academy of Sciences
2021-2023
Zhejiang University of Technology
2023
Ningxia Medical University
2021-2022
Osteoarthritis (OA) is an age-related degenerative disease, and its incidence increasing with the ageing of population. Metformin, as first-line medication for treatment diabetes, has received attention role in OA. The purpose present study was to confirm therapeutic effect metformin a mouse model OA determine mechanism underlying resultant delay progression. right knees 8-week-old C57BL/6 male mice were subjected destabilization medial meniscus (DMM). Metformin (200 mg/kg) then administered...
Cell lines and their corresponding expression plasmids are extensively utilized in the study of insect physiology pathology. In this research, four single-cell cultured (Px4-1 to Px4-4) Plutella xylostella were established from eggs. The promoter for P. elongation factor 1α (PxEF1α), known its high driving activity cells, was cloned used construct plasmids. Dual-luciferase assays EGFP analyses demonstrated that PxEF1α exhibited strongest Px4-2 comparable immediate-early 1 associated with...
Abstract The most-debated question in the investigation of spondyloarthropathies has been whether there is molecular mimicry between host HLA-B27 antigens and arthritis-causing pathogens. We have generated a monoclonal anti-HLA-B27 antibody our laboratory used radioimmunoassay to screen panel bacterial species. Two strains Yersinia pseudotuberculosis were found be highly reactive. cross-reactive component was identified by Western blot 19,000 component. A preparative sodium dodecyl...
Abstract Background Hydroxysafflor Yellow A (HSYA), which is one of the most important active ingredients Chinese herb Carthamus tinctorius L , widely used in treatment cerebrovascular and cardiovascular diseases. However, potential protective effect HSYA spinal cord ischemia/reperfusion (I/R) injury still unknown. Methods Thirty-nine rabbits were randomly divided into three groups: sham group, I/R group group. All animals sacrificed after neurological evaluation with modified Tarlov...
Osteoarthritis (OA) is a chronic, progressive and degenerative disease, its incidence increasing on yearly basis. However, the pathological mechanism of OA at each stage still unclear. The present study aimed to explore underlying dihydroartemisinin (DHA) in terms ability inhibit osteoclast activation, determine effects rats. Bone marrow‑derived macrophages were isolated as precursors. In presence or absence DHA, formation was assessed by tartrate‑resistant acid phosphatase (TRAP) staining,...
The essential oils, respectively, from fresh and dried Stropharia rugosoannulata fruiting bodies, an important edible mushroom, have been studied for their chemical composition, antibacterial capacity, antioxidant activity. oils were obtained by hydrodistillation analyzed gas chromatography-mass spectrometry (GC-MS) combined with Kovats retention index. oils’ test was evaluated the microdilution method against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, activity...
Abstract The β‐adrenergic‐like octopamine receptor (OA2B2) belongs to the class of G‐protein coupled receptors. It regulates important physiological functions in insects, thus is potentially a good target for insecticides. In this study, putative open reading frame sequence Pxoa2b2 gene Plutella xylostella was cloned. Orthologous alignment, phylogenetic tree analysis, and protein analysis all showed that cloned OA2B2 family. PxOA2B2 transiently expressed HEK‐293 cells. found could be...
Tyramine receptors (TARs) can be activated by tyramine (TA) or octopamine (OA) and have been shown to related physiological regulation (e.g., gustatory responsiveness, social organization, learning behavior) in a range of insect species. A receptor gene Plutella xylostella, Pxtar1, was cloned stably expressed the HEK-293 cell line. Pharmacological properties expression profile Pxtar1 were also analyzed. could activate PxTAR1 receptor, increasing intracellular Ca2+ concentration ((Ca2+)i) at...
Carbendazim and epoxiconazole are widely applied to control anthracnose sand bark fungal diseases in citrus. The residues of these two fungicides citrus their potential risk consumers have generated much public concern. We therefore sought investigate the dissipation, residue, dietary assessment carbendazim citrus.The dissipation kinetics residue levels under field conditions were measured using dispersive solid-phase extraction ultra-high-performance liquid chromatography-tandem mass...
Echinochloa crus-galli is a serious weed species in rice paddies. To obtain new potential bioherbicide, we evaluated the inhibitory activities of 13 essential oils and their active substances against E. crus-galli. Essential oil from Syzygium aromaticum (L.) Merr. & L. M. Perry (SAEO) exhibited highest herbicidal activity (EC50 = 3.87 mg mL-1) among evaluated. The SAEO was isolated at six different temperatures by vacuum fractional distillation, including 164°C, 165°C (SAEO-165), 169°C,...
p62 (also known as sequestosome 1) protein, is a small regulatory protein that accumulates in autophagy‑defective cells has been demonstrated to be involved the prognosis and survival of patients with several types cancer. However, best our knowledge, there have no such studies for osteosarcoma (OS). In present study, expression 70 OS samples was determined using immunohistochemistry its association various clinicopathological factors assessed. The results overexpression detected 77.1%...
Porcine parvovirus (PPV) is a single-stranded DNA virus that causes porcine reproductive failure. It of critical importance to study PPV pathogenesis for the prevention and control disease. NS1, non-structural protein, participated in viral replication, transcriptional regulation, cytotoxicity. Our previous research showed can activate nuclear factor kappa B (NF-κB) signaling pathway then up-regulate expression interleukin (IL)-6.Herein, purpose this determine whether protein NS1 also has...
Evaluations of the nutritional ingredients, biologically active materials, and pharmacological activities (antibacterial antioxidant) two types Stropharia rugosoannulata, grown under bamboo forest in greenhouse, respectively, were carried out this study. The ingredient tests included moisture, ash, crude protein, fat, fiber, total carbohydrates, sugar, mineral elements, vitamins, amino acids. material assays flavonoids, polysaccharides, triterpenoids, reducing sugars. In addition, a broth...
Abstract Introduction To compare the saliva proteomes of experimental Sjögren's syndrome (ESS) model mice and healthy controls to identify potential diagnostic biomarkers for primary (pSS). Methods Proteins were extracted from three ESS normal control using data‐independent acquisition technique. R language was used differentially expressed proteins (DEPs). Gene Ontology Kyoto Encyclopedia Genes Genomes pathway analyses performed functionally annotate DEPs. The protein–protein interaction...