Long Yan

ORCID: 0000-0002-5809-8974
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About
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Research Areas
  • Pesticide Exposure and Toxicity
  • Genomics and Phylogenetic Studies
  • Toxin Mechanisms and Immunotoxins
  • Identification and Quantification in Food
  • Transgenic Plants and Applications
  • Genetic diversity and population structure
  • Toxic Organic Pollutants Impact
  • Soybean genetics and cultivation
  • Pesticide and Herbicide Environmental Studies
  • Cholinesterase and Neurodegenerative Diseases
  • Amphibian and Reptile Biology
  • Carcinogens and Genotoxicity Assessment
  • Genetic Mapping and Diversity in Plants and Animals
  • Environmental Toxicology and Ecotoxicology
  • Insect and Pesticide Research
  • Marine Biology and Ecology Research
  • Metabolomics and Mass Spectrometry Studies
  • Traditional Chinese Medicine Analysis
  • Chromosomal and Genetic Variations
  • Machine Learning in Bioinformatics
  • Aquaculture disease management and microbiota
  • Sulfur Compounds in Biology
  • Food composition and properties
  • Plant Molecular Biology Research
  • Agronomic Practices and Intercropping Systems

Liaoning Ocean and Fisheries Research Institute
2022

Academy of Military Medical Sciences
2014-2016

Anhui Normal University
2014

Chinese Academy of Sciences
2010-2011

Institute of Botany
2010-2011

National Center for Gene Research
2011

State Key Laboratory of Plant Genomics
2010

Institute of Crop Sciences
2008

Chinese Academy of Agricultural Sciences
2008

Pollen development in flowering plants requires strict control of the gene expression program and genetic information stability by mechanisms possibly including miRNA pathway. However, our understanding pathway pollen remains limited, dynamic profile miRNAs developing is unknown. Using next-generation sequencing technology, we pyrosequenced small RNA populations from rice uninucleate microspores to tricellular sporophytic tissues at genome-wide level. We identified 292 known miRNAs, members...

10.1186/gb-2011-12-6-r53 article EN cc-by Genome biology 2011-06-01

The endosperm at the storage phase undergoes a series of coordinated cellular and metabolic events, including starchy cell death, starch synthesis, granule packaging, which leads to efficient accumulation starch. However, mechanism underlying interconnections remains unknown. We used integrated proteomic cytological approaches probe in rice (Oryza sativa) from 12 18 days after flowering (DAF). Starch packaging was completed first inner part 15 DAF spread almost entire DAF. Programmed death...

10.1021/pr900954p article EN Journal of Proteome Research 2010-08-17

The complete mitochondrial genome of Microhyl pulchra was determined in this work. This mitogenome 16,744 bp length, containing 13 protein-coding genes, 2 rRNA 22 tRNA genes and a control region (CR). following four distinctive features were observed: gene (ND1) began with GTG as start codon; eight (ND1, COII, ATP6, COIII, ND3, ND4, ND5 Cytb) ended incomplete stop codon T; positions (tRNA-Leu (CUN)/tRNA-Thr/Trna-Pro/tRNA-Phe) located between CR 12S which novel mtDNA rearrangement amphibians;...

10.3109/19401736.2013.869685 article EN Mitochondrial DNA Part A 2014-01-17

The Chinese leopard snake (Elaphe bimaculata) is an endemic species to China. complete nucleotide sequence of the mitochondrial (mt) genome E. bimaculata determined in this study. circle was 17,183 bp length and consisted 13 protein-coding genes, 22 transfer RNA 2 ribosomal genes duplicate control regions. Several peculiar features were observed mitogenome bimaculata, such as translocation tRNALeu(UUR) gene incomplete copy for tRNAPro.

10.3109/19401736.2014.945558 article EN Mitochondrial DNA Part A 2014-08-04

Ricin is a type II ribosome-inactivating protein toxin consisting of A and B chains linked by one interchain disulfide bond. Because its high toxicity depending on both together, confirming the presence intact ricin required during investigation illegal production application. Here, we report novel sensitive acetonitrile (ACN)-assisted trypsin digestion method for unambiguous identification simultaneous detection marker peptides from chains. Marker were generated with simple procedure direct...

10.1021/acs.jproteome.0c00458 article EN Journal of Proteome Research 2020-10-27

Both ricin and R. communisagglutinin (RCA120), belonging to the type II ribosome-inactivating proteins (RIPs-Ⅱ), are derived from seeds of castor bean plant. They share very similar amino acid sequences, but is much more toxic than RCA120. It urgently necessary distinguish RCA120 in response public safety. Currently, mass spectrometric assays well established for unambiguous identification by accurate analysis differentiated residues after trypsin digestion. However, diagnostic peptides...

10.3390/toxins11070393 article EN cc-by Toxins 2019-07-05

The Tiantai frog (Glandirana tientaiensis) is an endemic to China, which has been listed as endangered species in IUCN Red List of Threatened Species. In this study, the complete nucleotide sequence mitochondrial genome G. tientaiensis determined. circle 17,681 bp and consists 13 protein-coding genes, 22 transfer RNA 2 ribosomal genes 1 control region. Comparing with typical mtDNA family Ranidae, no distinctive rearrangement was found. Yet a obvious feature on use codon were observed, that 8...

10.3109/19401736.2014.936415 article EN Mitochondrial DNA Part A 2014-07-10

Methyl-diethanolamine (CAS: 105-59-9), ethyl-diethanolamine 139-87-7), and triethanolamine 102-71-6) were identified as the degradation products bio-markers of nitrogen mustard exposure.

10.1039/d3ra04697d article EN cc-by-nc RSC Advances 2023-01-01

Organophosphorus nerve agents inhibit the cholinesterase activity by phosphylation of active site serine. The resulting phosphylated and adducts on human serum albumin (HSA) are appropriate biomarkers for exposure. Several methods have been developed detection agents, including fluoride reactivation or alkaline cleavage. It was previously thought that some to HSA could not be detected via regeneration. In our study, results showed tabun (GA) sample preparation included acetone precipitation,...

10.4155/bio-2019-0161 article EN Bioanalysis 2019-11-15

The grey-backed thrush (Turdus hortulorum) is an endangered bird species, which mainly distributed in northern China, Korean Peninsula and Vietnam. In this study, the complete nucleotide sequence of mitochondrial genome T. hortulorum determined. circle was 16,759 bp length consisted 13 protein-coding genes, 22 transfer RNA 2 ribosomal genes 1 control region (D-loop). mtDNA similar to typical birds other vertebrates.

10.3109/19401736.2014.905849 article EN Mitochondrial DNA Part A 2014-04-08

Both ricin and R. communis agglutinin (RCA120), belonging to the type II ribosome-inactivating proteins (RIPs-Ⅱ), are derived from seeds of castor bean plant. They share very similar amino acid sequences, but is much more toxic than RCA120. It urgently necessary distinguish RCA120 in response public safety. Currently, mass spectrometric assays well established for unambiguous identification by accurate analysis differentiated residues after trypsin digestion. However, diagnostic peptides...

10.20944/preprints201906.0088.v1 preprint EN 2019-06-11

Sulfur mustard [HD; bis-(2-chloroethyl) sulfide] and other analogues are a kind of highly toxic vesicant have been prohibited by the Organization for Prohibition Chemical Weapons (OPCW) since 1997. Exposures to HD could generate several adducts in plasma hydrolysis products urine, which widely applied as biomarkers identify exposure forensic analysis. Several methods developed detection related biomarkers. However, most based on complex derivatization, not enough attention is paid analogues....

10.1021/acs.chemrestox.3c00170 article EN Chemical Research in Toxicology 2023-09-01
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