- Cardiovascular and Diving-Related Complications
- High Altitude and Hypoxia
- Neuroscience of respiration and sleep
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiovascular and exercise physiology
- Heart Rate Variability and Autonomic Control
- Cardiovascular Syncope and Autonomic Disorders
- Obstructive Sleep Apnea Research
- Respiratory Support and Mechanisms
- Gestational Diabetes Research and Management
- Cardiac Arrest and Resuscitation
- Vitamin C and Antioxidants Research
- Cardiovascular Effects of Exercise
- Pregnancy and preeclampsia studies
- Injury Epidemiology and Prevention
- Hemodynamic Monitoring and Therapy
- Cardiovascular Issues in Pregnancy
- Vagus Nerve Stimulation Research
- Lower Extremity Biomechanics and Pathologies
- Adenosine and Purinergic Signaling
- Maternal and fetal healthcare
- EEG and Brain-Computer Interfaces
- Neonatal and fetal brain pathology
- Heme Oxygenase-1 and Carbon Monoxide
- Sports Performance and Training
Aix-Marseille Université
2014-2025
Inserm
2019-2025
Université de Toulon
2004-2025
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2020-2025
Unité de recherche sur les maladies cardiovasculaires et métaboliques
2020-2022
This study investigated the sources of physiological stress in diving by comparing SCUBA dives (stressors: hydrostatic pressure, cold, and hyperoxia), apneic (hydrostatic physical activity, hypoxia), dry static apnea (hypoxia only). We hypothesized that despite hypoxia induces a long apnea, it would be less stressful than dive or since latter combined high cold exposure. Blood samples were collected from 12SCUBA 12 divers before after dives. On different occasion, group maximal apnea....
Intravenous (i.v.) injections of adenosine exert marked effects on heart rate (HR) and arterial blood pressure (BP), but the role an endogenous release by vagal stimulation has not been evaluated. In anaesthetized rats, we examined HR BP changes induced 1 min electrical in control condition, then after i.v. (i) atropine, (ii) propranolol, (iii) caffeine, (iv) 8 cyclopentyl-1,3-dipropylxanthine (DPCPX), or (v) dipyridamole to increase plasma concentration (APC). APC was measured...
Although the role of underwater phases is well-known, no study has taken an interest in describing and quantifying distance time spent apnea as a condition for optimal performance. This aimed to investigate impact surface parameters on swimming performance elite swimmers. The performances 79 swimmers 100-m freestyle were analyzed (short-course). spatiotemporal three groups have been recorded: finalists 2018 World Swimming Championships (WORLD), French who reached 100 m under 50 s at National...
Head-up tilt test is useful for exploring neurally mediated syncope. Adenosine an ATP derivative implicated in cardiovascular disturbances that occur during head-up test. The aim of the present study was to investigate impact hyperoxia on adenosine plasma level and hemodynamic changes induced by testing. Seventeen healthy male volunteers (mean age 35 ± 11 years) were included study. experiment consisted 2 tests, 1 session with subjects breathing, through a mask, medical air (FiO2 = 21%)...
Immersion pulmonary edema (IPE) is a serious complication of water immersion during scuba diving. Myocardial ischemia can occur IPE that worsens outcome. Because myocardial injury impacts the therapeutic management, we aim to evaluate profile cardiac markers (creatine phosphokinase (CPK), brain natriuretic peptide (BNP), highly sensitive troponin T (TnT-hs) and ultrasensitive I (TnI-us) divers with IPE. Twelve male admitted for suspected were included. The collection blood samples was...
It is well known that the duration of apnea longer in static than dynamic conditions, but impact exercise intensity on needs to be investigated. The aim this study was determine relationship between and intensity, associated metabolic parameters. Ten healthy active young non-apnea trained (NAT) men participated study. During first visit, they carried out a maximum (SA) maximal progressive cycle evaluate power output achieved at peak oxygen uptake (PVO2peak). second performed four randomized...
The physiopathology consequences of hypoxia during breath-hold diving are a matter debate. Adenosine (AD), an ATP derivative, is suspected to be implicated in the adaptive cardiovascular response apnea, because its vasodilating and bradycardic properties, two clinical manifestations observed voluntary apnea. aim this study was evaluate adenosine apnea-induced trained spearfishermen (SFM) who used perform repetitive dives for 4-5 h. Twelve SFM (11 men 1 woman, mean age 41 ± 3 years, apnea...