A5047272501- Folate and B Vitamins Research
- Regulation of Appetite and Obesity
- Bee Products Chemical Analysis
- Adipose Tissue and Metabolism
- Ovarian function and disorders
- Coffee research and impacts
- Biological Activity of Diterpenoids and Biflavonoids
- Atherosclerosis and Cardiovascular Diseases
- Metabolism, Diabetes, and Cancer
- Phosphodiesterase function and regulation
- Thermoregulation and physiological responses
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Estrogen and related hormone effects
- Global Maritime and Colonial Histories
- Diabetes Treatment and Management
- Sleep and related disorders
- Diet, Metabolism, and Disease
- Natural Antidiabetic Agents Studies
- Chemokine receptors and signaling
- Phytochemistry and Bioactivity Studies
- Acne and Rosacea Treatments and Effects
- Insect Utilization and Effects
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Cell Adhesion Molecules Research
- Wound Healing and Treatments
Applied Science Private University
2017-2023
Therapeutics Clinical Research
2020
Al-Ahliyya Amman University
2012
Universitat de València
2007-2010
The incidence of cardiovascular diseases in premenopausal women is lower than men or postmenopausal women. This study reports the discovery a low grade systemic inflammation, including monocyte adhesion to arterial endothelium, elicited by menopause estrogen depletion. Chronic treatment with dose 17-beta-estradiol inhibition renin-angiotensin system reduced this inflammation. Using an vitro flow chamber human and venous endothelial cells, we found that leukocytes from healthy were more...
Abstract Angiotensin II (Ang-II) displays inflammatory activity and is implicated in several cardiovascular disorders. This study evaluates the effect of cis- trans (t)-resveratrol (RESV) two vivo models vascular inflammation identifies cardioprotective mechanisms that underlie them. In vivo, Ang-II–induced arteriolar leukocyte adhesion was inhibited by 71% t-RESV (2.1 mg/kg, i.v.), but not affected cis-RESV. Because estrogens influence rennin-angiotensin system, chronic treatment with (15...
Abstract Angiotensin II (Ang-II) is associated with atherogenesis and arterial subendothelial mononuclear leukocyte infiltration. We have demonstrated that Ang-II causes the initial attachment of cells to arteriolar endothelium. now report on contribution CC chemokines this response. Intraperitoneal administration 1 nM induced MCP-1, RANTES, MIP-1α generation, maximal at 4 h, followed by recruitment 8 24 h. Using intravital microscopy within rat mesenteric microcirculation h after exposure...
The present study addressed the effects of investigational PDE4 inhibitor roflumilast on leukocyte-endothelial cell interactions and endothelial permeability in vivo vitro.In vivo, intravital video-microscopy was used to determine p.o. microvascular rat mesenteric venules. In vitro, N-oxide, active metabolite humans, other inhibitors neutrophil adhesion tumour necrosis factor alpha (TNFalpha)-activated human umbilical vein cells (HUVEC), E-selectin expression thrombin-induced evaluated. Flow...
Background Hyperglycemia is acknowledged as an independent risk factor for developing diabetes-associated atherosclerosis. At present, most therapeutic approaches are targeted at a tight glycemic control in diabetic patients, although this fails to prevent macrovascular complications of the disease. Indeed, it remains highly controversial whether or not mere elevation extracellular D-glucose can directly promote vascular inflammation, which favors early pro-atherosclerotic events. Methods...
Objectives Polycystic ovary syndrome (PCOS) is a common metabolic and endocrine disorder in females their reproductive-age associated with clinical complications. The aim of this study was to evaluate the knowledge perception women Jordan about PCOS, its symptoms, diagnosis treatment. Methods A descriptive, cross-sectional that designed order assess female knowledge, perceptions PCOS Jordan. carried out through validated questionnaire 227 number recruited participants. Results result showed...
Sleep deprivation is a common health problem that growing rapidly worldwide and it associated with short- long-term impacts on health. The aim of this study was to detect potential predictors salivary testosterone (sT) association sleep in Arab male university students. In prospective cohort study, 77 students the age range 18 26 years were divided into two groups, sleep-deprived (SD) participants non-sleep-deprived (NSD) participants. defined as sleeping less than 5 hr per night. Blood...
Objective: To investigate the associations of coffee consumption and/or smoking on certain clinical outcomes including total cholesterol (TC), high-density lipoprotein (HDL-C), low-density (LDL-C), vitamin B12, and folic acid in a population young healthy men. Method: This cross-sectional study was conducted Amman, Jordan, over 4 months. Participants were approached for participation asked to fill questionnaire about their anthropometric information, habitual smoking, during last 3 Their...
Studies on the effect of body weight and coffee consumption leptin, vitamin B12, folic acid are scarce conflicting. This study investigates and/or rate serum levels these molecules in healthy young adult males.This observational cross-sectional was carried out at faculty pharmacy, Applied Science Private University (ASU), Amman, Jordan, from July to September 2020. Young males were invited participate fill a questionnaire regarding lifestyle habits including during last 3 months, medical...