A5000159096- Collagen: Extraction and Characterization
- 3D Printing in Biomedical Research
- Bone Tissue Engineering Materials
- Tendon Structure and Treatment
- Additive Manufacturing and 3D Printing Technologies
- Osteoarthritis Treatment and Mechanisms
- Angiogenesis and VEGF in Cancer
- Knee injuries and reconstruction techniques
- Electrospun Nanofibers in Biomedical Applications
- Shoulder Injury and Treatment
- Tissue Engineering and Regenerative Medicine
- Periodontal Regeneration and Treatments
Geistlich Pharma (Switzerland)
2018-2024
Collagen is the main structural element of connective tissues, and its favorable properties make it an ideal biomaterial for regenerative medicine. In dental medicine, collagen barrier membranes fabricated from naturally occurring tissues are used guided bone regeneration. Since morphological characteristics play a crucial role in their mechanical affect cellular behavior at defect site, in-depth knowledge structure key. As base development novel membranes, extensive analysis four porcine...
Pathological angiogenesis is a crucial attribute of several chronic diseases such as cancer, age-related macular degeneration, and osteoarthritis (OA). In the case OA, pathological mediated by vascular endothelial growth factor (VEGF), among other factors, contributes to cartilage degeneration implants rejection. line with this, use anti-VEGF bevacizumab (BVZ) has been shown prevent OA progression support regeneration. The aim this work was functionalize medical grade collagen poly...
The most prevalent extracellular matrix (ECM) protein in the meniscus is collagen, which controls cell activity and aids preserving biological structural integrity of ECM. To create stable high-precision 3D printed collagen scaffolds, ink formulations must possess good printability cytocompatibility. This study aims to overlap limitation printing pure develop a highly concentrated for fabrication. extrusion test revealed that 12.5 % had best combination high concentration printability. was...
Meniscus tears have been treated using partial meniscectomy to relieve pain in patients, although this leads the onset of early osteoarthritis (OA). Cell-based therapies can help preserve meniscus, presence inflammatory cytokines compromises clinical outcomes. Anti-inflammatory drugs (e.g. celecoxib), reduce patients and vitro studies suggest a beneficial effect on cytokine inhibited matrix content. Previously, we demonstrated that inhibitory effects IL-1β be countered by culture under low...