A5091431332- Nosocomial Infections in ICU
- Pneumonia and Respiratory Infections
- Sepsis Diagnosis and Treatment
- Antibiotic Use and Resistance
- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
- Immune Response and Inflammation
- Healthcare Decision-Making and Restraints
- Intensive Care Unit Cognitive Disorders
- Antibiotics Pharmacokinetics and Efficacy
- Antimicrobial Resistance in Staphylococcus
- Meta-analysis and systematic reviews
- Statistical Methods in Clinical Trials
- Neonatal and Maternal Infections
- Clostridium difficile and Clostridium perfringens research
- Healthcare cost, quality, practices
- COVID-19 Pandemic Impacts
- Cardiac, Anesthesia and Surgical Outcomes
- Antimicrobial Peptides and Activities
- Inhalation and Respiratory Drug Delivery
- Diabetes Management and Research
- Emergency and Acute Care Studies
- Monoclonal and Polyclonal Antibodies Research
- Neutropenia and Cancer Infections
- Bariatric Surgery and Outcomes
Ballarat Health Services
2016-2025
The University of Melbourne
2016-2025
Deakin University
2024-2025
Federation University
2021-2025
WinnMed
2025
Grampians Health
2023-2024
Bank of England
2021
University of Maryland, Baltimore
2020
University of Maryland Baltimore Washington Medical Center
2020
Peninsula Health
2020
Although infections caused by methicillin-resistant Staphylococcus aureus with reduced vancomycin susceptibility (SA-RVS) have been reported from a number of countries, including Australia, the optimal therapy is unknown. We reviewed clinical features, therapy, and outcome 25 patients serious due to SA-RVS in Australia New Zealand. Eight had endocarditis, 9 bacteremia associated deep-seated infection, 6 osteomyelitis or septic arthritis, 2 empyema. All received before isolation SA-RVS,...
Laparoscopic 90 degrees anterior partial fundoplication for gastroesophageal reflux disease achieves equivalent results to laparoscopic Nissen fundoplication.A multicenter, prospective, double-blind randomized clinical trial with a minimum of 5 years' follow-up.Nine university teaching hospitals in 6 major cities throughout Australia and New Zealand.One hundred twelve patients undergoing primary antireflux surgery were undergo either (52 patients) or (60 patients).Laparoscopic division the...
Ultrasound-guided peripheral vascular access was rarely used by Certified Registered Nurse Anesthetists (CRNA) within a large academic hospital since the use of ultrasound had not been common practice among CRNAs. The purpose this quality improvement project to develop an educational intervention increase for CRNAs 20% while also improving their knowledge, comfort, and confidence in using technology. A pre-intervention survey revealed limited practicing CRNAs, despite benefits enhanced...
The herd effects of antimicrobial interventions used to prevent ICU-acquired infections are unknown. objective here was estimate these within a single three-tiered cluster randomized trial (CRT) emulated using ventilator-associated pneumonia (VAP) data from concurrent control trials (RCCTs) abstracted Cochrane reviews. Control and intervention group derived 13 reviews 72 RCCTs antibiotic (Tier 3) antiseptic 2) decontamination versus 109 various non-decontamination 1, serving as benchmark)...
Cluster-randomized trials (CRTs) are able to address research questions that randomized controlled (RCTs) of individual patients cannot answer. Of great interest for infectious disease physicians and infection control practitioners relating the impact interventions on dynamics at whole-of-population level. However, there important conceptual differences between CRTs RCTs design, analysis, inference. These can be illustrated by adage "peas in a pod." Does question relate "peas" (the patients)...
Abstract Whether Candida within the patient microbiome drives pathogenesis of Staphylococcus aureus bacteremia, described as microbial hitchhiking, cannot be directly studied. Group-level observations from studies various decontamination and non-decontamination-based ICU infection prevention interventions without study (observational groups) collectively enable tests this interaction causal models. Candidate models propensity for bacteremia to arise with versus antibiotic, anti-septic,...
The effects of plasma and chromogenic substrate on the kinetics endotoxin-activated Limulus amoebocyte lysate (LAL) assay were determined. A linear correlation was observed between rate development turbidity (optical density 405) with LAL reagent concentration endotoxin over a four log ten-fold range. Like substrate, addition dilution heat treated to reaction resulted in an increase optical proportional present. presence also accelerated comparable results when testing at different...
Abstract Background : Paracetamol is a component of number drugs taken in overdose (OD). The influence alcohol use (acute or chronic) on the presentation and clinical course paracetamol OD contentious. This study explores relationship between OD, consumption outcomes at regional Australian hospital. Aims To determine frequency, circumstances presentations to general hospital over 4‐year period. Methods Medical records patients admitted Ballarat Health Services (BHS) as result January 2000...
Background: Stress hyperglycemia and hypoglycemia are associated with increased morbidity mortality in the critically ill. Intermittent, random blood glucose (BG) measurements can miss episodes of hyper- hypoglycemia. The purpose this study was to determine accuracy Symphony® continuous monitor (CGM) ill cardiac surgery patients. Methods: Fifteen adult patients were evaluated immediately postoperatively intensive care unit. Prelude® SkinPrep prepared skin a sensor applied 2 test sites on...