A5012557019- Neurobiology and Insect Physiology Research
- Animal Behavior and Reproduction
- Insect and Arachnid Ecology and Behavior
- Insect Utilization and Effects
- Genomics and Rare Diseases
- Coleoptera Taxonomy and Distribution
- Forensic and Genetic Research
- CRISPR and Genetic Engineering
- Insect-Plant Interactions and Control
- Insect Resistance and Genetics
- Parasite Biology and Host Interactions
- Health, Environment, Cognitive Aging
- Aquaculture Nutrition and Growth
- Science, Research, and Medicine
- Animal Genetics and Reproduction
- Insect symbiosis and bacterial influences
- Genetic diversity and population structure
- Genomics and Phylogenetic Studies
- RNA and protein synthesis mechanisms
- Muscle Physiology and Disorders
- Evolution and Genetic Dynamics
- Hemiptera Insect Studies
- Scarabaeidae Beetle Taxonomy and Biogeography
- Genetics, Aging, and Longevity in Model Organisms
- Plant and animal studies
Boston University
2025
Indiana University Bloomington
2016-2023
Organisms cope with nutritional variation via developmental plasticity, adjusting trait size to nutrient availability for some traits while enabling others develop in a nutritionally robust manner. Yet, the mechanisms that regulate organ-specific growth across gradients remain poorly understood. We assessed functions of members insulin/insulin-like signalling pathway (IIS) regulation nutrition sensitivity and robustness males horn-polyphenic beetle Onthophagus taurus , as well potential...
Abstract Niche construction occurs when organisms modify their environments and alter selective conditions through physiology behaviours. Such modifications can bias phenotypic variation enhance organism–environment fit. Yet few studies exist that experimentally assess the degree to which environmental shape developmental fitness outcomes, how influences may differ among species identify underlying proximate mechanisms. Here, we eliminate from environment of Onthophagus dung beetles. We show...
Polyphenism is a type of developmental plasticity that translates continuous environmental variability into discontinuous phenotypes. Such discontinuity likely requires switch between alternative gene-regulatory networks, principle has been borne out by mechanisms found to promote morph-specific gene expression. However, whether robustness required execute polyphenism decision awaited testing at the molecular level. Here, we used nematode model for polyphenism, Pristionchus pacificus ,...
Nutrition-dependent growth of sexual traits is a major contributor to phenotypic diversity, and large body research documents insulin signalling as regulator nutritional plasticity. However, findings across studies raise the possibility that role individual components within pathway diverges in function among taxa. Here, we use RNAi-mediated transcript depletion gazelle dung beetle investigate functions forkhead box O (Foxo) two paralogs receptor (InR1 InR2) shaping plasticity polyphenic...
Abstract Developmental polyphenism, the ability to switch between phenotypes in response environmental variation, involves alternating activation of environmentally sensitive genes. Consequently, understand how a polyphenic evolves requires comparative analysis components that make up networks. Here, we inferred coexpression networks for morphological feeding-structure dimorphism nematode Pristionchus pacificus. In this species, individuals produce alternative forms novel trait—moveable...
Phenotypic plasticity is a fundamental property of developing organisms and thought to play an important role in diversification. Plastic responses themselves are remarkably diverse respond wide range environmental factors. Here I focus on response variation nutrition insects since 1) widespread factor that impacts most organisms, 2) models study phenotypic plasticity. First, provide brief overview our current mechanistic understanding the regulation nutritionally cued insects, both...
Recent genetic studies and whole-genome sequencing projects have greatly improved our understanding of human variation clinically actionable information. Smaller ethnic populations, however, remain underrepresented in both individual large-scale efforts hence present an opportunity to discover new variants biomedical demographic significance. This report describes the analysis a genome obtained from Serbian origin, introducing tens thousands previously unknown currently available pool....
Recent genetic studies and whole-genome sequencing projects have greatly improved our understanding of human variation clinically actionable information. Smaller ethnic populations, however, remain underrepresented in both individual large-scale efforts hence present an opportunity to discover new variants biomedical demographic significance. This report describes the analysis a genome obtained from Serbian origin, introducing tens thousands previously unknown currently available pool....