A5034456336- Neonatal Respiratory Health Research
- Respiratory Support and Mechanisms
- Infant Nutrition and Health
- Neuroscience of respiration and sleep
- Breastfeeding Practices and Influences
- Neonatal and fetal brain pathology
- Congenital Diaphragmatic Hernia Studies
- Airway Management and Intubation Techniques
- Emergency and Acute Care Studies
- Nosocomial Infections in ICU
- Metabolism and Genetic Disorders
- Cardiac Arrest and Resuscitation
- Neonatal Health and Biochemistry
- Child and Adolescent Health
- Infant Development and Preterm Care
- Antibiotics Pharmacokinetics and Efficacy
- Trauma and Emergency Care Studies
- Pediatric Hepatobiliary Diseases and Treatments
- Esophageal and GI Pathology
- Gastroesophageal reflux and treatments
- Vitamin K Research Studies
- Gallbladder and Bile Duct Disorders
- Mitochondrial Function and Pathology
- Antibiotic Use and Resistance
- Child Nutrition and Feeding Issues
Rainbow Children's Hospital
2012-2024
L V Prasad Eye Institute
2021
Boston Children's Hospital
2013-2014
During the current rapidly evolving pandemic of COVID-19 infection, pregnant women with suspected or confirmed and their newborn infants form a special vulnerable group that needs immediate attention. Unlike other elective medical surgical problems for which care can be deferred during pandemic, pregnancies childbirths continue. Perinatal period poses unique challenges mother-baby dyads requires resources prevention transmission, diagnosis infection providing clinical labor, resuscitation...
Background Mechanical power (MP) refers to the energy transmitted over time respiratory system and serves as a unifying determinant of ventilator-induced lung injury. MP normalization is required account for developmental changes in children. We sought examine relationship between mechanical (ME BW ), normalized body weight (MP compliance CRS ) concerning severity outcomes pediatric acute distress syndrome (pARDS). Method In this retrospective study, children aged 1 month 18 years diagnosed...
Preterm babies thrive well on exclusive breastfeeding with fewer complications. In a retrospective analysis, challenges were noticed in the form of delayed first milk expression and frequency expression, which was limited to 2-3 times day. A quality improvement initiative designed increase breast feeding rates admitted preterm babies. The purpose present study is evaluate proportion neonates receiving mother's own by day 7 life after such an initiative.The conducted at level 3 neonatal...
To study if protocolized monitoring of endotracheal tube (ETT) cuff pressure every 6 hours is better than adjusting inflation by the only bedside clinical assessment.This was a single-center prospective randomized controlled done between July 1, 2017 and March 31, 2019. Children 1 month 18 years, intubated with cuffed ETT our trained doctors were included. After obtaining consent, patients into two groups, standard group (SG) (MG). Sample size calculated 80 in each power 80%, significance...
Background: The rates of "any" human milk use in neonatal intensive care units have improved during the last decade. However, efforts to help mothers expressing and maintaining mother's own (MOM) through discharge remain a concern. This study aims improve MOM preterm neonates. Methods: was quality improvement (QI) initiative conducted from May 2018 April 2019. All neonates <34 weeks were included. In "initiation phase" (May August 2018), breastfeeding support group formed given structured...
<p><strong>Background</strong>: CPAP refers to the application of positive pressure airway a spontaneously breathing infant throughout respiratory cycle.</p><p><strong>Objectives</strong>: To study clinical pattern in neonate</p><p><strong>Method</strong>: Total 75 patient were enrolled study, 38 nasal mask and 37 prongs group. The result was analysed by using Fisher exact test unpaired t for continuous...
Aim: Mother's own milk (MOM) is the preferred source of neonatal nutrition. Due to various challenges, mothers are often unable provide exclusive MOM neonates admitted in intensive care units (NICUs) and depend on pasteurized donor human (PDHM). The aim this quality improvement (QI) initiative was enable consequently decrease "PDHM dependency." Methods: Neonates <32 weeks gestation (n = 120) were included. A multidisciplinary team formed, a detailed root cause analysis done understand PDHM...
Background: There are few studies on unplanned extubation (UE) in pediatric intensive care units (PICU). This study is to identify factors associated with UE PICUs. Subjects and Methods: In this observational study, the data of from January 1, 2013, May 31, 2019, a level-4 PICU were analyzed an objective etiology its impact therapeutic outcomes. Results: Of 7079 patients hospitalized PICU, 1721 invasively ventilated (mean ventilator days 4.33 days). occurred 39 (2.26% intubated patients) at...
Methylenetetrahydrofolate reductase (MTHFR) deficiency is a rare autosomal recessive inherited inborn error of metabolism, which presents with various severity depending on the level residual enzyme activity. In neonates, it can present recurrent hypoventilation episodes, persistent encephalopathy or without microcephaly. MTHFR also results in hyperhomocysteinemia, homocystinuria and hypomethionemia. We report male neonate severe presenting to us third week life progressive encephalopathy,...
Cow's milk protein allergy (CMPA) is the most common food in infants. A previously healthy neonate fed with infant formula presented diarrhoea, vomiting and respiratory distress cyanosis. Investigations showed thrombocytosis leucocytosis lymphocyte predominance. To our surprise blood gas analysis metabolic acidosis a high methaemoglobin level of 33% (normal range <3%). Clinical status, returned to normal following fluid resuscitation methylene blue administration. The was later managed...
Aicardi-Goutières syndrome (AGS) induces innate immune activation. It can present with cerebral calcifications and hepatosplenomegaly mimicking congenital infections. The case report discusses the diagnosis treatment of a fetal cardiomyopathy whose postnatal symptoms resembled TORCH (toxoplasmosis, other agents, rubella, cytomegalovirus, herpes syphilis) infection. mother had history two lost pregnancies due to same was identified in current pregnancy. At 34 weeks gestation, delivered late...