A5049420630- Nuclear materials and radiation effects
- Computational Drug Discovery Methods
- Fullerene Chemistry and Applications
- Radiation Shielding Materials Analysis
- Hepatitis C virus research
- Glass properties and applications
- Monoclonal and Polyclonal Antibodies Research
- Boron and Carbon Nanomaterials Research
- HIV/AIDS drug development and treatment
- Chemical Synthesis and Analysis
- Chemical Reaction Mechanisms
- Chemical Reactions and Mechanisms
- Click Chemistry and Applications
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Synthesis and Properties of Aromatic Compounds
- Synthesis and biological activity
- Graphite, nuclear technology, radiation studies
- Inorganic and Organometallic Chemistry
- Diamond and Carbon-based Materials Research
- PARP inhibition in cancer therapy
- Advanced Physical and Chemical Molecular Interactions
- Advances in Oncology and Radiotherapy
- Organizational Leadership and Management Strategies
- High-pressure geophysics and materials
Imam Abdulrahman Bin Faisal University
2019-2024
Cairo University
2009-2019
The current study aims to explore the shielding properties of multi-component borate-based glass series. Seven glass-samples with composition (80-y)H3BO3–10ZnO–10Na2O–yBaO where (y = 0, 5, 10, 15, 20, 25 and 30 mol.%) were synthesized by melt-quench method. Various features for photons, neutrons, protons determined all prepared samples. XCOM, Phy-X program, SRIM code performed determine explain several such as equivalent atomic number, exposure build-up factor, specific gamma-ray constants,...
A Fullerene based system is modified in order to increase its solubility and enhance ability carry a protein-like structure. The structure, which proposed act as HIV-1 protease inhibitor, [C60–C2H4N–(2,4- XCOCH2OH)C6H4], where the X atom either O, S or Se. geometry optimization, vibrational spectra thermodynamics were performed using semiempirical quantum mechanical PM3 method study compounds. Furthermore, quantitative structure activity relationship (QSAR) properties of compounds are...
This study explores change management strategies to implement digital assessments in higher education institutions Malaysia, with a particular focus on University Islam Selangor. It addresses the ongoing global shift towards assessment and challenges specific such as resistance from metric lecturers inadequate frameworks. Through mixed-methods approach, research investigates current state of implementation, factors influencing acceptance resistance, proposes foster smoother transitions. The...
This study investigates the use of metacognitive writing strategies among master's students in English departments at Yemeni universities, focusing on their role enhancing academic proficiency. Using a quantitative descriptive design, data were collected from 30 master’s Sana’a and Aden universities through validated questionnaire. The findings reveal that while demonstrate strong awareness planning, monitoring, evaluating work, they face challenges applying advanced cohesive devices such as...
Two novel groups of hexapeptide inhibitors for NS3 serine protease the hepatitis C virus (HCV) are designed. The is an amino acid sequence NS5A/NS5B substrate (Glu-Asp-Val-Val-Cys-Cys). In first group, binds to a cellulose monomer at positions 2, 3 or 6 while in second dimmer 3, 6, 2', 3' 6'. Molecular modeling semiemprical PM3 calculations used optimize geometry and calculate electronic properties suggested compared that natural substrate. Computational results show group has maximum...
This work investigates the possibility of improving biological activity Telaprevir; an HCV NS3 protease inhibitor. is carried out through suggestion 11 modified compounds Telaprevir and calculating their electronic Quantitative Structure Activity Relationship (QSAR) parameters using molecular modeling via PM3 method. Results show that compound number 6 (with 1,3dithiolane ring at position R2) has more favorable QSAR compared to Telaprevir. Therefore, this would be considered as a promising novel HVC
Based on the N-terminal hexapeptide product of hydrolysis (EDVVCC) at HCV NS5A/5B junction, three modified groups compounds are built. The first group contains linear peptides while second and third contain P1-P3 P2-P4 macrocyclic structures, respectively. Quantitative Structure Activity Relationship (QSAR) characterization docking simulations performed in order to investigate potential these as NS3/4A protease inhibitors. QSAR properties, most stable due their lowest total energy...
The aim of this study is to ascertain the possible application Random Amplification Polymorphic DNA (RAPD) analysis as a genetic test investigate polymorphisms and detection genomic markers in various types leukemia. results showed unique profiles amplified fragments produced three leukemia by an arbitrary primer decamer oligonucleotides OPA-09. four (980, 1659, 2187 3162 bp). smallest fragment (980 bp) appeared 14.3 13.3% tested acute myeloid chronic patients, respectively; but was absent...
Abstract Lithium borate (LB) glasses doped with dysprosium oxide (Dy 2 O 3 ) have been prepared by utilizing the conventional melt‐quench technique. The glass samples were exposed to 60 Co check their dosimetric features and kinetic parameters. These involve glow curves, annealing, fading, reproducibility, minimum detectable dose (MDD), effective atomic number ( Z eff ). Kinetic parameters including frequency factors activation energy also determined using three methods (glow curve analysis,...