A5074331772- Nuclear Physics and Applications
- Radiation Detection and Scintillator Technologies
- Boron Compounds in Chemistry
- Atomic and Subatomic Physics Research
- Radiation Therapy and Dosimetry
- Nuclear reactor physics and engineering
- Fusion materials and technologies
- Advanced Radiotherapy Techniques
- Magnetic confinement fusion research
- Advanced Semiconductor Detectors and Materials
- Luminescence Properties of Advanced Materials
- Boron and Carbon Nanomaterials Research
- Nuclear Materials and Properties
- Particle accelerators and beam dynamics
- Chemical Synthesis and Characterization
- Advanced X-ray and CT Imaging
- Diamond and Carbon-based Materials Research
- Medical Imaging Techniques and Applications
- Heat Transfer Mechanisms
- Engineering Applied Research
- High-pressure geophysics and materials
- Heat transfer and supercritical fluids
- Fluid Dynamics and Turbulent Flows
- Heat Transfer and Optimization
- Welding Techniques and Residual Stresses
Nagoya University
2016-2024
Kyoto University
2017
Instituto de Investigaciones Químicas
2017
RIKEN
2017
Fukui University of Technology
2017
The deuterium operation of the large helical device (LHD) began in March 7, 2017, after long-term preparation and commissioning apparatuses necessary for execution experiment. A comprehensive set neutron diagnostics was developed installed onto LHD through numerous efforts preparation. Neutron play an essential role both yield management radiation safety extension energetic-particle physics study LHD. flux monitor (NFM) characterized by fast-response wide dynamic range capabilities is...
In situ calibration of the neutron activation system on Large Helical Device (LHD) was performed by using an intense 252Cf source. To simulate a ring-shaped source, we installed railway inside LHD vacuum vessel and made train loaded with source run along typical magnetic axis position. Three capsules thirty pieces indium foils stacked total mass approximately 18 g were prepared. Each capsule irradiated over 15 h while circulating. The response coefficient (9.4 ± 1.2) × 10−8 115In(n,...
Boron neutron capture therapy (BNCT) requires pharmaceutical innovations and molecular-based evidence of effectiveness to become a standard cancer therapeutic in the future. Recently, Japan, 4-borono-L-phenylalanine (BPA) was approved as boron agent for BNCT against head neck (H&N) cancers. H&N appears be suitable target BPA-BNCT, because expression levels L-type amino acid transporter 1 (LAT1), one transporters responsible BPA uptake, are elevated most cases cancer. However, other types...
Abstract Accelerator-driven neutron sources have been developed worldwide for boron capture therapy (BNCT) instead of nuclear reactors. Nagoya University is currently developing a compact DC accelerator driven BNCT system using sealed lithium (Li) target. The target receives high heat load by proton beam, and the then requires efficient removal. This study high-efficiency removal technique that uses V-shaped staggered ribs on side flow channels. We performed experiments an electron beam to...
Neutron emission anisotropy caused by neutral beam injection was observed the neutron activation measurement in deuterium plasmas confined Large Helical Device. The shot-integrated fast flux measured irradiation of foils at two ends located different ports. ratio outside horizontal port to that lower used as an index anisotropy. dependence on direction confirmed comparing cases tangential, perpendicular and both tangential injections. numerically evaluated assuming these three injection....
Eu:CaF 2The development of a neutron detector for real-time measurements in an intense field is desired.We are developing quartz optical-fiber-based as monitor.Thus far, Eu:LiCaAlF 6 crystals and LiF/Eu:CaF 2 eutectics have been used the scintillators detectors.These high light yields, but relatively long decay time constants, which limiting factors dynamic range detectors.In this work, we applied small Li glass scintillator to using optical fiber with numerical aperture UV-curable resin...
This paper presents the method to evaluate fast neutron energy spectrum under mixed radiation field using single crystal CVD diamond detector. The pulse shape discrimination based on and width of was applied extract event in which hits at a specific depth diamond. Unfolding measured deposition induced by extracted pulses could deduce spectrum. An experiment 14.1 MeV mono-energetic source demonstrated reliable capability this quantitatively.
To monitor an actual dose in a patient's body during radiotherapy treatment, we have developed small-size dosimeter of optical fiber probe mounting optically stimulated luminescence (OSL) materials at the tip.The OSL show quenching effect when they are irradiated by charged particles with high linear energy transfer (LET).We evaluate particle dependence on probe.Eu:BaFBr and Ce:CaF 2 were adopted as materials, two types fabricated.We 290 MeV/u carbon ions, 150 helium 225 MeV protons measured...
We developed a thermal neutron source for performance tests of boron agents Boron Neutron Capture Therapy (BNCT) at exposure Accelerator System Biological Effect Experiments (NASBEE) in National Institute Radiological Sciences, Japan. The flux the experimental position was measured to be 2.18× 108 n/cm2/s, cadmium ratio 9.21, and gamma ray dose rate 2.11 Gy/h. estimated 2.96 These values indicate that can applicable although application range is limited. An example irradiation experiment described.
Abstract Boron neutron capture therapy (BNCT) is an innovative cancer that selectively destroys only cells by utilizing the reaction between boron agents, which accumulate in cells, and beams. However, irradiation field BNCT a mixture of multiple radiation types, making accurate dose evaluation difficult. For tissue, particularly important, it essential to discriminate neutrons γ -rays mixed measure them correctly. In this paper, we introduce new method for selective measurement using...
The global flux distributions for thermal, epithermal and fast neutrons in the torus hall of large fusion devices were experimentally evaluated first time Large Helical Device (LHD) using activation foil method measured by imaging plate high-purity germanium detector. It turned out that thermal effectively absorbed borated polyethylene blocks placed beneath LHD. This should reduce radioactivity floor would be beneficial maintaining a good environment radiation workers. Uniform observed near...
The Nagoya University Accelerator-driven Neutron Source (NUANS) is an accelerator-based neutron source by 7Li(p,n)7Be reaction with a 2.8 MeV proton beam up to 15 mA. fast neutrons are moderated and shaped Beam Shaping Assembly (BSA). NUANS aiming at the basic study of Boron Capture Therapy (BNCT) such as in vitro cell-based irradiation experiment using water phantom. Moreover, BSA developed prototype one for human treatment. We have evaluated radiation field Monte Carlo code PHITS. It...