A5007387157- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Hepatitis C virus research
- Radiomics and Machine Learning in Medical Imaging
- Palliative Care and End-of-Life Issues
- Musculoskeletal Disorders and Rehabilitation
- Emergency and Acute Care Studies
- Systemic Lupus Erythematosus Research
- Electrolyte and hormonal disorders
- Renal cell carcinoma treatment
- Adolescent and Pediatric Healthcare
- Mental Health and Psychiatry
- Grief, Bereavement, and Mental Health
- Gastrointestinal disorders and treatments
- Lymphatic Disorders and Treatments
- Cancer, Lipids, and Metabolism
- Healthcare Decision-Making and Restraints
- Organ Transplantation Techniques and Outcomes
- Migration, Health and Trauma
- interferon and immune responses
- Patient Dignity and Privacy
- Antimicrobial Resistance in Staphylococcus
- RNA regulation and disease
- Pancreatic and Hepatic Oncology Research
Stanford Medicine
2023-2024
Stanford University
2023-2024
University of California, San Francisco
2019-2023
University of Mississippi Medical Center
2023
Jackson Memorial Hospital
2023
University of California, Los Angeles
2017
Successful host defense against pathogens requires innate immune recognition of the correct pathogen associated molecular patterns (PAMPs) by receptors (PRRs) to trigger appropriate gene program tailored pathogen. While many PRR pathways contribute response specific pathogens, relative importance each pathway for complete transcriptional elicited has not been examined in detail. Herein, we used RNA-sequencing with wildtype and mutant macrophages delineate contributing early Staphylococcus...
In patients with HCC awaiting liver transplantation (LT), there is a need to identify biomarkers that are superior AFP in predicting prognosis. AFP-L3 and des-gamma-carboxyprothrombin (DCP) play role detection, but their ability predict waitlist dropout unknown. this prospective single-center study commenced July 2017, 267 had all 3 obtained at LT listing. Among them, 96.2% received local-regional therapy, 18.8% an initial tumor stage beyond Milan criteria requiring downstaging. At listing,...
More than a dozen countries have now legalized some form of assisted dying, and additional jurisdictions are considering similar legislations or expanding eligibility criteria. Despite the persistent controversies about relationship between medicine, palliative care, many people interested in dying. Understanding how end-of-life care discussions patients specialist providers may be affected by such legislation can inform delivery evolving socio-cultural legal environment.To explore Canadian...
Background: Serum AFP- L 3%, A FP, and D CP are useful biomarkers for HCC detection, but their utility in assessing treatment response remains unknown. We aim to evaluate the accuracy of a biomarker model detection posttreatment viable tumors. Methods: For derivation, recipients with undergoing liver transplant from 2018 2022 who had collected within 3 months before were included. developed generalized linear detecting tumors as covariates, which we termed “LAD Score.” An independent cohort...
Volume overload and ascites, or the accumulation of fluid in abdomen, is a debilitating manifestation chronic liver disease portal hypertension that associated with reduced survival quality life.1,2 In patients compensated cirrhosis, ascites occur 5%–10% per year, its onset key indicator hepatic decompensation progression disease.3 The presence volume and, specifically, increases risk additional complications, including malnutrition, infection, electrolyte imbalance, hepatorenal syndrome....
The RETREAT (Risk Estimation of Tumor Recurrence after Transplant) Score is a validated tool to predict post-transplant HCC recurrence risk. AFP bound Lens culinaris agglutinin (AFP-L3) and des-gamma-carboxyprothrombin (DCP) measured at transplant worse post-LT survival may improve the score.