A5100367944- Glaucoma and retinal disorders
- Retinal Development and Disorders
- Reproductive tract infections research
- Retinal Diseases and Treatments
- Endoplasmic Reticulum Stress and Disease
- Immune cells in cancer
- 2D Materials and Applications
- Nerve injury and regeneration
- Antifungal resistance and susceptibility
- Syphilis Diagnosis and Treatment
- Intraocular Surgery and Lenses
- Chemokine receptors and signaling
- Luminescence Properties of Advanced Materials
- Atherosclerosis and Cardiovascular Diseases
- Cellular transport and secretion
- Parasitic Diseases Research and Treatment
- Nail Diseases and Treatments
- Perovskite Materials and Applications
- Corneal surgery and disorders
- Medical and Biological Sciences
- ZnO doping and properties
- Ga2O3 and related materials
- Hereditary Neurological Disorders
- Winter Sports Injuries and Performance
- Retinal and Macular Surgery
Huazhong University of Science and Technology
2004-2024
First Affiliated Hospital of Hebei Medical University
2022
Hebei Medical University
2022
Union Hospital
2004-2019
Shriners Hospitals for Children
2016
Temple University
2014-2015
Temple University Hospital
2013
Fu Wai Hospital
2011
Axon injury is an early event in neurodegenerative diseases that often leads to retrograde neuronal cell death and progressive permanent loss of vital functions. The connection these two obviously sequential degenerative events, however, elusive. Deciphering the upstream signals trigger neurodegeneration cascades both soma axon would be a key step toward developing effective neuroprotectants are greatly needed clinic. We showed previously optic nerve injury-induced endoplasmic reticulum (ER)...
Understanding the molecular mechanism of glaucoma and development neuroprotectants is significantly hindered by lack a reliable animal model that accurately recapitulates human glaucoma. Here, we sought to develop mouse for secondary often observed in humans after silicone oil (SO) blocks pupil or migrates into anterior chamber following vitreoretinal surgery. We significant intraocular pressure (IOP) elevation intracameral injection SO, SO removal allows IOP return quickly normal. This...
Abstract In contrast to conventional atomic crystals, two‐dimensional inorganic molecular crystals (2DIMCs) possess a unique crystal structure composed of small molecules held together by van der Waals force. Such distinctive grants them specific chemical and physical properties highly suitable for electronic optoelectronic applications. However, the synthesis 2DIMCs has posed significant challenges due inherent issues such as uncontrollable growth orientation stemming from their natural...
Abstract Understanding the molecular mechanism of glaucoma and development neuroprotectants are significantly hindered by lack a reliable animal model that accurately recapitulates human glaucoma. Here we sought to develop mouse for secondary is often observed in humans after silicone oil (SO) blocks pupil or migrates into anterior chamber following vitreoretinal surgery. We similar intraocular pressure (IOP) elevation intracameral injection eyes SO, removing SO allows IOP level quickly...
Abstract Objective This study analyzed the effect of HDAC inhibitor, trichostatin A (TSA), in inducing granulocyte–macrophage colony-stimulating factor (GM-CSF)-mediated bone marrow (BM) cell differentiation to myeloid-derived suppressor cells (MDSCs) vitro and vivo. Methods BM CD11b + GR-1 MDSCs was achieved by culture with TSA GM-CSF, collected were mixed lymphocyte identify suppressive actions against effector T cells. RT-PCR ELISA conducted analyze CCL5 mRNA protein levels GM-CSF BM,...
MiR-424 has been demonstrated to inhibit the expression of its target protein Nuclear factor I-A (NFI-A) in monocytes and promote differentiation macrophages hemopoiesis. This is also one pivotal steps atherosclerosis. Whether miR-424 a potential role atherosclerosis still unknown. Isoflavone proved be an agonist PPARγ play anti-atherosclerotic roles by reducing level IL-6 TNF-α vitro . We assessed hypothesis that might participate progression inhibiting NFI-A promoting macrophages. reduce...
Objective Explore the feasibility of applying sandwich teaching method in clinical ophthalmology.Methods Of 120 five-year-program students on medicine who were at their education stage Affiliated Union Hospital Tongji Medical College,Huazhong University Science and Technology,60 Were chosen random as experimental group rest study group.The recorded studyfeelings part ofthe homework finished a questionnaire end.The teachers tested theoretical practicing ability two groups blindly.Results...