- Craniofacial Disorders and Treatments
- Cleft Lip and Palate Research
- Facial Trauma and Fracture Management
- Head and Neck Surgical Oncology
- Reconstructive Surgery and Microvascular Techniques
- Tracheal and airway disorders
- Anatomy and Medical Technology
- Surgical Simulation and Training
- Tumors and Oncological Cases
- Bone fractures and treatments
- Breast Implant and Reconstruction
- Traumatic Ocular and Foreign Body Injuries
- Spinal Fractures and Fixation Techniques
- Anesthesia and Neurotoxicity Research
- Airway Management and Intubation Techniques
- Anomaly Detection Techniques and Applications
- Silk-based biomaterials and applications
- COVID-19 and healthcare impacts
- Image and Object Detection Techniques
- Temporomandibular Joint Disorders
- Teratomas and Epidermoid Cysts
- Medical Image Segmentation Techniques
- Fetal and Pediatric Neurological Disorders
- Skin and Cellular Biology Research
- Diversity and Career in Medicine
Seattle Children's Hospital
2024
University of Pittsburgh Medical Center
2020-2024
Children's Hospital of Pittsburgh
2020-2024
University of Pittsburgh
2020-2024
Primary Children's Hospital
2024
University of Utah
2014-2024
University of Washington
2024
Florida Craniofacial Institute
2024
UPMC Health System
2023
Creative Commons
2016-2023
The incidence of auricular deformities is believed to be ∼11.5 per 10,000 births, excluding children with microtia. Although not life-threatening, can cause undue distress for patients and their families. surgical procedures have traditionally been used reconstruct congenital deformities, ear molding has gaining acceptance as an efficacious, noninvasive alternative the treatment newborns deformations. We present successful correction bilateral Stahl's deformity in a newborn through...
Background: Quantifying the severity of head shape deformity and establishing a threshold for operative intervention remains challenging in patients with metopic craniosynostosis (MCS). This study combines three-dimensional skull analysis an unsupervised machine-learning algorithm to generate quantitative score (cranial morphology deviation) provide score. Methods: Head computed tomography scans from subjects MCS normal controls (5 15 months age) were used objective using ShapeWorks software...
Background: Pre-operative computer-aided design and manufacturing (CAD/CAM) revolutionized head neck reconstruction after extirpative surgery. However, studies performing head-to-head comparison to the conventional technique have limited long-term follow-up. We aimed compare short outcomes between CAD/CAM approaches for mandibular with free fibula flaps. Methods: Patients undergoing flap from 2012 2021 were included. Data regarding patient demographics, past medical history, surgical...
Introduction: The diagnosis and management of metopic craniosynostosis involves subjective decision-making at the point care. purpose this work is to describe a quantitative severity metric point-of-care user interface aid clinicians in provide platform for future research through deep phenotyping. Methods: Two machine-learning algorithms were developed that quantify – supervised model specific (Metopic Severity Score) an unsupervised used cranial morphology general (Cranial Morphology...
Epoprostenol (also called prostaglandin, PGI) is used for pulmonary hypertension in newborns with congenital diaphragmatic hernia (CDH) some centers. The effects of PGI on survival CDH were examined.A retrospective analysis the Congenital Diaphragmatic Hernia Study Group registry between 2007and 2011 was performed. Patient-level logistic regression applied a subset 29 hospitals history use to relate probability death within 7 days surgery after controlling ethnicity, prenatal diagnosis,...
Persistent velopharyngeal insufficiency (VPI) following primary palatoplasty remains a difficult problem to treat. This study evaluates speech outcomes revision with tissue augmentation using buccal myomucosal flaps (BMF) as an alternative pharyngoplasty for patients VPI.A retrospective single-center review of at tertiary pediatric hospital Cleft-Craniofacial Center between January 2017 and March 2021 was conducted. Patients history previous palatoplasty, diagnosis persistent or recurrent...
Abstract Recently, several adjunctive procedures have gained traction to aid cleft surgeons in repairing especially challenging palatal clefts. Buccal fat flaps and buccal myomucosal demonstrated particular utility reinforcing thin or tissue deficits. Although their use has not been widely accepted, they may be particularly helpful the setting of significant scarring vascular compromise. Here authors describe case an intraoperative salvage using bilateral a right flap after transection...
The COVID-19 pandemic had multiple effects on the provision of health care, including suspension elective and nonessential surgeries. objective this study was to determine early effect surgical care patients with cleft lip and/or palate at a high-volume center.A retrospective comparative cohort undergoing adhesion, nose repair, palatoplasty before during conducted. There were 50 in prepandemic 53 cohort.Mean age adhesion 3.1 ± 1.1 months (n = 8) 3.5 2.5 (P 0.75). One delayed by 1.6 months....
Posterior cranial vault distraction (PCVD) has become an important modality in the management of complex craniosynostosis to increase intracranial volume and improve appearance. This technique can safely be performed as early 3 months age for initial patients with craniosynostosis. A retrospective review was all syndromic, multiple-suture synostosis treated PCVD at Primary Children's Hospital Salt Lake City, Utah, between 2012 2014. During this time period, a total nine children average...
Background: Nasoorbitoethmoid (NOE) fractures impact growth of the craniofacial skeleton in children, which may necessitate differentiated management from adult injuries. This study describes characteristics, management, and outcomes NOE children seen at a single institution. Methods: A retrospective review patients under 18 years who presented to our institution 2006 2021 with facial was conducted; were included. Data collected included demographics, mechanism injury, fracture type,...
Objective The endoscopic endonasal approach (EEA) is commonly employed in skull base surgery for neoplasm resection. While nasal deformity following EEA described, this study aimed to perform a detailed qualitative and quantitative assessment of the associated saddle nose (SND) particular. Setting/Participants This retrospective review 20 adult patients with SND after resection tumors over 5-year period at University Pittsburgh Medical Center. Main Outcome Measures Fifteen measurements...
De novo heterozygous mutations in the KAT6A gene give rise to a distinct intellectual disability syndrome, with features including speech delay, cardiac anomalies, craniofacial dysmorphisms, and craniosynostosis. Here, we reported 16-year-old girl novel pathogenic variant of gene. She is first case possess pancraniosynostosis, rare suture fusion pattern, affecting all her major cranial sutures. The diagnosis syndrome established via recognition its inherent phenotypic utilization whole exome...
Abstract Bilateral lambdoid and sagittal synostosis, or Mercedes Benz Syndrome, is a rare complex craniosynostosis resulting in frontal bossing, tapered posterior fossa, an anteriorly displaced cranial vertex. Its ideal surgical correction must result expansion, skull elongation, caudal repositioning of the We present craniometric analysis changes with posterior-superior distraction introduce novel measure: vertex position. In this study, retrospective review was performed to analyze...
Background: Unilateral lambdoid craniosynostosis is differentiated from deformational plagiocephaly primarily by assessing the cranium posterior and bird’s-eye views. Findings include displacement of ipsilateral ear, occipitomastoid bossing, occipitoparietal flattening, contralateral parietal frontal bossing. Diagnosis based off facial morphology may be an easier approach because face less obstructed hair head-coverings, can easily assessed when supine. However, frontofacial characteristics...
Despite a greater awareness of the differential diagnosis head shape abnormalities among pediatricians, effect deformational forces on calvarial morphology can complicate craniosynostosis. In this report, we describe 2 patients diagnosed with unicoronal craniosynostosis (UCS) in delayed fashion due to presence concomitant posterior plagiocephaly (PDP). both cases, severity each patients' PDP obscured changes typically associated UCS. This unique presentation underscores importance having...
Background Pierre Robin Sequence (PRS) is characterized by micrognathia, glossoptosis, and upper airway obstruction. Early recognition appropriate perinatal management crucial for optimizing outcomes. This study aimed to evaluate 20-week fetal ultrasounds determine if specific mandibular measurements could predict PRS diagnosis disease severity. Methods A retrospective case-control of 48 patients with gender-matched controls was performed. Medical records were reviewed respiratory surgical...
Purpose: CranioRate™ is a deep-phenotyping machine learning tool used to quantify morphologic severity in craniosynostosis. We present an analysis of the largest metopic craniosynostosis patient cohort date understand spectrum while identifying alterations clinically appreciable skull regions. Methods: provides two objective, holistic metrics for quantifying craniosynostosis: Metopic Severity Score (MSS) and Cranial Morphology Deviation (CMD). De-identified CTs from normal patients multiple...
Pediatric craniofacial fractures are fundamentally distinct from their adult counterparts because of unique injury patterns and effects on future growth. Understanding context informs management risk mitigation. Previous studies include only inpatients, operative patients, or specialty-specific. In contrast, our study presents a comprehensive assessment all pediatric facial fracture patients seen at single institution. Patients under 18 years old who were evaluated for level I trauma center...
PURPOSE: CranioRate™ is a machine learning tool designed to assess craniosynostosis severity by analyzing cranial morphology. This study examines the largest metopic patient group date, aiming understand and identify affected skull regions. METHODS: provides two objective, holistic metrics for quantifying in craniosynostosis: Metopic Severity Score (MSS) Cranial Morphology Deviation (CMD). De-identified CTs from normal patients multiple U.S. institutions were compiled analyzed using...
In pediatric patients with mandible fractures and concomitant cervical spine injury (CSI), treatment strategies may occasionally compete: condylar require functional therapy range of motion exercises the temporomandibular joint (TMJ), while CSI requires neck immobilization. The authors report case a child presenting bilateral head fractures, right parasymphyseal fracture, treated collar immobilization, who ultimately developed TMJ ankylosis. Here, review mandibular fracture management...
PURPOSE: Pre-operative virtual surgical planning (VSP) through computer-aided design and modeling (CAD/CAM) is an emerging technology that revolutionized the way we approach head neck reconstruction after extirpative surgery. It has been particularly useful in osteocutaneous free tissue transfer for complex defects as a method to improve accuracy, operative efficiency, osseous union with less adverse outcomes. Given relatively recent introduction, studies performing head-to-head comparison...
Exposure to plastic surgery in preclinical years of medical school is extremely limited. It the interest field educate all students about so that otherwise excellent candidates are not excluded because inexperience and a capable diverse student body can be identified early mentored closely. Furthermore, with increasing competitiveness integrated training programs,1 it advantageous for able decide apply residency earlier.2 Our goal was create an opportunity learn through lectures, engage...