A5063735927- Per- and polyfluoroalkyl substances research
- Chemical Analysis and Environmental Impact
- Hemoglobinopathies and Related Disorders
- Toxic Organic Pollutants Impact
- Engineering and Materials Science Studies
- Prenatal Screening and Diagnostics
- Water Treatment and Disinfection
- Viral Infectious Diseases and Gene Expression in Insects
- Cytomegalovirus and herpesvirus research
- Lysosomal Storage Disorders Research
- Analytical Chemistry and Chromatography
- Metabolism and Genetic Disorders
- Physics and Engineering Research Articles
- Analytical Chemistry and Sensors
- Metabolomics and Mass Spectrometry Studies
- Cholesterol and Lipid Metabolism
- Ocular and Laser Science Research
- Blood groups and transfusion
- RNA regulation and disease
- Phosphorus and nutrient management
- Neurogenetic and Muscular Disorders Research
- Wastewater Treatment and Nitrogen Removal
- Innovative Microfluidic and Catalytic Techniques Innovation
- Analytical chemistry methods development
- Protein purification and stability
Heidelberg University
2019-2024
University Hospital Heidelberg
2019-2023
DVGW - Technologiezentrum Wasser
2017-2019
Karlsruhe University of Education
2019
Biochemical Society
2013
University College London
2013
A novel selective solid–liquid extraction of PFASs from oxidized batches the total oxidizable precursor (TOP) assay enables a complete mass balance by inclusion ultrashort-chain PFASs.
Early diagnosis of severe combined immunodeficiency (SCID), spinal muscular atrophy (SMA), and sickle cell disease (SCD) improves health outcomes by providing a specific treatment before the onset symptoms. A high-throughput nucleic acid-based method in newborn screening (NBS) has been shown to be fast cost-effective early detection these diseases. Screening for SCD included Germany's NBS Program since Fall 2021 typically requires laboratories adopt analytical platforms that are demanding...
The need to bring new biopharmaceutical products market more quickly and reduce final manufacturing costs is driving early stage, small scale bioprocess development. This work describes a comprehensive engineering characterisation of novel, single-use 24-well parallel miniature bioreactor system. Cell culture performance also investigated, with particular focus on the aeration strategies adopted at this (7 mL) either by headspace sparging alone or direct gas into medium. Apparent volumetric...
Sickle cell disease (SCD) is a group of hemoglobinopathies with common point mutation causing the production sickle hemoglobin (HbS). In high-throughput newborn screening (NBS) for SCD, two-step procedure suitable, in which qPCR first pre-selects relevant samples that are differentiated by second method.Three NBS centers using qPCR-based primary SCD performed laboratory comparison. Methods tandem MS or HPLC were used differentiation.In benchmarking test, 450 dried blood analyzed. Samples...