María Martínez

ORCID: 0000-0002-6308-4243
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About
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Research Areas
  • Oral microbiology and periodontitis research
  • Salivary Gland Disorders and Functions
  • Oral Health Pathology and Treatment
  • Streptococcal Infections and Treatments
  • Dental Radiography and Imaging
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Dental materials and restorations
  • Dental Health and Care Utilization
  • Tryptophan and brain disorders
  • Alzheimer's disease research and treatments
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • HIV/AIDS oral health manifestations
  • Cannabis and Cannabinoid Research
  • Gut microbiota and health
  • Sphingolipid Metabolism and Signaling
  • Acute Myocardial Infarction Research
  • Anatomy and Medical Technology
  • Dental Implant Techniques and Outcomes
  • Scientific and Engineering Research Topics
  • Sepsis Diagnosis and Treatment
  • Stress Responses and Cortisol

Universidad Complutense de Madrid
2020-2025

Hospital Universitario de Fuenlabrada
2020

Hospital Universitario Miguel Servet
2017

Abstract Aim To analyse, through a pre‐clinical in vivo model, the possible mechanisms linking depression and periodontitis at behavioural, microbiological molecular levels. Materials methods Periodontitis (P) was induced Wistar:Han rats (oral gavages with Porphyromonas gingivalis Fusobacterium nucleatum ) during 12 weeks, followed by 3‐week period of Chronic Mild Stress (CMS) induction. Four groups ( n = rats/group) were obtained: CMS (P+CMS+); without CMS; periodontitis; control....

10.1111/jcpe.13420 article EN Journal Of Clinical Periodontology 2021-01-15

Abstract Aim To explore the potential mechanisms of neuroinflammation (microglia, blood–brain barrier [BBB] permeability, and sphingosine‐1‐phosphate [S1P] pathways) resulting from association between periodontitis depression in rats. Materials Methods This pre‐clinical vivo experimental study used Wistar rats, which (P) was induced by using oral gavages with Porphyromonas gingivalis Fusobacterium nucleatum. Then, a chronic mild stress (CMS) model implemented to induce depressive‐like...

10.1111/jcpe.13780 article EN Journal Of Clinical Periodontology 2023-01-16

ABSTRACT Aim To evaluate in vitro the antibacterial efficacy and cytocompatibility of different implant‐decontamination methods, using both 2D 3D peri‐implant mucosa models. Methods Four decontamination methods [chlorhexidine (CHX), electrolytic treatment (GS), curcumin (CUR), xanthohumol (XN)] were compared four independent experiments, three with a model on titanium surfaces another model. These procedures tested for their effect multispecies biofilm Streptococcus oralis , Actinomyces...

10.1111/clr.14410 article EN Clinical Oral Implants Research 2025-01-29

Abstract Aim To determine the impact of periodontal treatment on systemic markers inflammation in patients with metabolic syndrome (MetS) and periodontitis. Materials Methods In this parallel‐arm, double‐blind, randomized controlled clinical trial, 63 MetS severe periodontitis were randomly assigned to receive either intensive (IPT; scaling root planing plus azithromycin 500 mg every day for 3 days) or minimal (MPT; supragingival professional mechanical plaque removal a placebo). The primary...

10.1111/dom.14131 article EN Diabetes Obesity and Metabolism 2020-07-02

To determine the usefulness of myeloperoxidase in discriminating between patients with acute coronary syndrome and chest pain by other causes.The study included all over 18 years age who come consecutively to emergency department from September 2015 December non-traumatic origin. The initial patient evaluation was performed according protocol for suspected (ACS) our Emergency Department. This serial measurement troponin, this case myeloperoxidase, serialization on admission at 6h. For...

10.1016/j.acmx.2017.11.003 article EN cc-by-nc-nd Archivos de cardiología de México 2017-12-07

Abstract Aims Periodontitis and cardiovascular diseases (CVD) are highly prevalent non‐communicable diseases, sharing an inflammatory pathogenesis common risk factors. The objective of the present research is to assess association between periodontitis disease in a representative sample Spanish‐employed population. Methods Cross‐sectional data were obtained 2008 2011 Workers' Oral Heal th (WORALTH) epidemiological study. Periodontal examinations based on evaluation clinical attachment loss...

10.1111/jre.13340 article EN cc-by-nc-nd Journal of Periodontal Research 2024-08-22

Abstract Background Although there is evidence of positive effect periodontal therapy on systemic inflammation, this response highly variable among subjects. It was the aim clinical investigation to determine impact treatment markers inflammation in patients with metabolic syndrome (MetS) and periodontitis. Methods In parallel-arm, double blind, randomized controlled trial, 63 MetS severe periodontitis were randomly assigned receive intensive (IPT; scaling root planing plus azithromycin 500...

10.21203/rs.3.rs-25563/v1 preprint EN cc-by Research Square (Research Square) 2020-05-05

ABSTRACT Aim To assess the correlation between micro‐computed tomography (micro‐CT) and linear morphometric measurements in terms of mandibular bone levels a modified experimental periodontitis model rodents to study mechanisms association periodontal destruction neuroinflammation. Methods The proposed vivo involves administration oral rinses with Porphyromonas gingivalis Fusobacterium nucleatum, four times per week during 4, 8 or 12 weeks, 24 male Wistar Hannover rats (180 g, 5 weeks old)....

10.1111/jre.13354 article EN cc-by-nc-nd Journal of Periodontal Research 2024-10-22

Immediate full-arch loading is a highly complex and technique-sensitive procedure. Digital impression techniques aim to replace conventional analog systems carry out dental treatments in more predictive, safer, less time-consuming way. This case report describes patient with guarded periodontal prognosis, who was rehabilitated implant-supported fixed prostheses after full-mouth extractions. performed by means of two digital systems: photogrammetric technology PIC the maxillary arch,...

10.3290/j.qi.b4083477 article EN PubMed 2023-11-28
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