- Monoclonal and Polyclonal Antibodies Research
- Chronic Lymphocytic Leukemia Research
- Immunodeficiency and Autoimmune Disorders
- Immunotherapy and Immune Responses
- Protein purification and stability
- Lymphoma Diagnosis and Treatment
- RNA Interference and Gene Delivery
- T-cell and B-cell Immunology
- Viral Infectious Diseases and Gene Expression in Insects
- Influenza Virus Research Studies
The Francis Crick Institute
2017
Ragon Institute of MGH, MIT and Harvard
2017
Centenary Institute
2000
International Centre for Genetic Engineering and Biotechnology
1997
Vaccines remain the most effective tool to prevent infectious diseases. Here, we introduce an in vitro booster vaccination approach that relies on antigen-dependent activation of human memory B cells culture. This stimulation induces antigen-specific cell proliferation, differentiation into plasma cells, and robust antibody secretion after a few days We validated this strategy using from healthy donors retrieve antibodies against tetanus toxoid influenza hemagglutinin (HA) H1N1 newly...