A5101630001- Hepatitis B Virus Studies
- Hepatitis C virus research
- Acute Myeloid Leukemia Research
- Blood groups and transfusion
- Cancer therapeutics and mechanisms
- Acute Lymphoblastic Leukemia research
- HIV, Drug Use, Sexual Risk
- Hemoglobinopathies and Related Disorders
- Blood donation and transfusion practices
- Liver Disease Diagnosis and Treatment
- Gut microbiota and health
- HIV/AIDS Research and Interventions
- Antibiotic Resistance in Bacteria
- Systemic Lupus Erythematosus Research
- Online and Blended Learning
- Connexins and lens biology
- HIV/AIDS drug development and treatment
- Histone Deacetylase Inhibitors Research
- Agricultural Systems and Practices
- Ovarian function and disorders
- Advanced Breast Cancer Therapies
- RNA Interference and Gene Delivery
- Pharmacological Effects of Natural Compounds
- Platelet Disorders and Treatments
- Enterobacteriaceae and Cronobacter Research
Aga Khan University
2025
Harbin Medical University
2024-2025
International Islamic University, Islamabad
2014-2023
University of Sargodha
2021-2023
King's College London
2023
Rashid Latif Medical College
2021
Jinnah Postgraduate Medical Center
2019
University of the Punjab
2019
Government College University, Faisalabad
2019
Pakistan Institute of Medical Sciences
2019
Pakistan has a high prevalence of oral cavity cancer (OCC) with significant recurrence rate. This study aims to explore the factors associated OCC in Karachi, Pakistan. cross-sectional was conducted at Aga Khan University Hospital (AKUH) Pakistan, using data from AKUH Cancer Registry. A total 1692 biopsy-confirmed cases including cancers mucosal lip, tongue, gum, floor, palate and other subsites like retromolar area, diagnosed between May 2011 December 2020, were included our study. Of...
Abstract Liver plays vital role in detoxification of exogenous and endogenous chemicals. These chemicals as well oxidative stress may cause liver disorders. This study was aimed to evaluate the hepatoprotective effects various fractions Aconogonon alpinum methanolic extract against carbon tetrachloride (CCl 4 )-induced toxicity mice. First, potential A. assessed then antioxidant activity profiling polyphenolic compounds were assessed. A total 78 male albino mice (BALB/c) randomly divided...
Infection with the Hepatitis B virus (HBV) continues to be one of leading healthcare issues in Pakistan, affecting over 6 million people. The existence HBsAg mutants is well documented many countries. In HBV screening majority blood banks performed by Rapid Detection Devices or ELISA tests. These tests are designed detect HBsAg, but may not mutant HBsAg. Failure result transmission infection from donor recipient. Hence, there a need identify assay which can country where simple and...
Hepatitis B virus (HBV) is a major causative agent of early, severe and prolonged liver infection that subsequently leads to cirrhosis hepatocellular carcinoma. The aim this study was evaluate the molecular epidemiology hepatitis genotypes comparison serological assay performance versus polymerase chain reaction (PCR) in HBV screening.Blood samples 8517 healthy blood donors were collected during period January June 2017 from Blood Bank Shaheed Zulfiqar Ali Bhutto Medical University,...
Pseudomonas aeruginosa is one of the major pathogens associated with acute tissue damage in patients having Diabetic Foot Ulcer (DFU). The treatment such infections can be an uphill battle due to serious resistance all mainstay antibiotics, owing overzealous production Extended-Spectrum Beta-Lactamases (ESBLs). Pakistan also has a high prevalence diabetes and complications related it, however genetic disposition remains underinvestigated.The main objective study was determine frequency ESBLs...
Introduction: The development of alloantibodies is a major problem among thalassemia individuals due to periodic blood transfusions. current study assessed the frequency and specificity erythrocytes alloimmunization also variables affecting extent in repeatedly transfused patients. Materials Methods: This prospective, cross-sectional was conducted at Department Blood Transfusion Services Thalassemia Centre Pakistan Institute Medical Sciences from August 2017 February 2018. Of 475 patients,...
Human Parainfluenza virus (HPIV) causes lower respiratory tract infections (LRTI) mostly in young children. Respiratory viral may decline T cells circulation and display enhanced pathogenicity. This study is aimed to analyze alterations due HPIV children with LRTIs. Children (N = 152) bronchitis or pneumonia, admitted tertiary care hospitals were included the study. samples (throat nasopharyngeal swabs) taken genotypes (1-4) analyzed through RT-PCR. Peripheral blood cells, CD3+, CD4+, CD8+,...
Aims: This study was planned to evaluate the trends of transfusion-transmissible infectious diseases (TTID). Setting and Design: cross-sectional retrospective conducted on donor community attending Transfusion Medicine Department, Punjab Institute Cardiology, Lahore, Pakistan from January 1, 2012, December 31, 2016. Subject Methods: A total 79,774 blood donors were processed for HbsAg anti-HCV, anti-human immunodeficiency virus (HIV), syphilis, malaria detection by rapid immune...
This report provides long-term results of the treatment patients with newly-diagnosed AML a single high dose mitoxantrone combined once daily cytarabine. One-hundred and sixty-five treated on four studies high-dose mitoxantrone-based induction therapy are included. Patients prior antecedent hematologic disorder were eligible. The median follow-up time is 65.9 months (95% CI: 55.7–86.2 months). overall complete remission rate was 64%, responses in 78% less than 60 years age 51% or older....
Objective: The aim of this study was to evaluate the frequency iron deficiency anemia among blood donors. Methods: A prospective, single center cross-sectional conducted in Department Blood Transfusion Services, Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad, Pakistan, from February 2017 June 2017. total 528 donors who donated without prior screening for hemoglobin levels were enrolled study. samples tested six hematological and five biochemical parameters including level, red...
Background: There are 33 blood groups identified so far representing more than 300 antigens. The transfusion services in resource-limited countries including Pakistan only test for ABO and RhD antigens during cross-matching. However, the of ABO-RhD compatible but unknown phenotype may result alloimmunization, especially multi-transfused patients. Aims: aim this study is to investigate prevalence clinically significant minor group population Islamabad, Pakistan. Settings Design: A prospective...
Chronic Hepatitis C Virus (HCV) infection is still a major health issue especially in endemic areas where fewer direct-acting virals (DAAs) are treatment options. Some HCV variants associated with resistance and it reduces DAAs success pre-existing prevail. In this study, we investigated resistance-associated polymorphisms (RAPs) the NS3 region from naïve Pakistani patients. 277 chronic patients infected genotype 1a, 3a 3b were selected various clinical centers capital city of Khyber...
Hepatitis B virus (HBV) is the aetiological agent of transfusion-transmitted hepatitis globally. Beta thalassaemia major individuals are at greater risk contracting HBV infection due to multiple blood transfusions required for medical management these patients. Based on genetic variability, it divided into 10 genotypes. The determination genotypes has significant implications clinical and treatment regimens.This study was performed assess epidemiology circulating in multi-transfused...