A5039058250- Cancer, Stress, Anesthesia, and Immune Response
- Anesthesia and Pain Management
- Neuropeptides and Animal Physiology
- Anesthesia and Neurotoxicity Research
- Stress Responses and Cortisol
- Pain Mechanisms and Treatments
- Spine and Intervertebral Disc Pathology
- Sleep and Wakefulness Research
- Cardiac, Anesthesia and Surgical Outcomes
- CAR-T cell therapy research
- Heparin-Induced Thrombocytopenia and Thrombosis
- Delphi Technique in Research
- Intensive Care Unit Cognitive Disorders
- Mindfulness and Compassion Interventions
- Sleep and Work-Related Fatigue
- Venous Thromboembolism Diagnosis and Management
- Airway Management and Intubation Techniques
- Respiratory Support and Mechanisms
- Vascular Anomalies and Treatments
- Hemodynamic Monitoring and Therapy
- Cardiac Arrest and Resuscitation
- Hemostasis and retained surgical items
- Cancer Immunotherapy and Biomarkers
- Enhanced Recovery After Surgery
- Anesthesia and Sedative Agents
Moffitt Cancer Center
2020-2024
Brigham and Women's Hospital
2024
University of South Florida
2021-2023
A.T. Still University
2021
Marymount University
2010
University of Michigan
2010
Background Sleep apnea, hypertension, atherosclerosis, and obesity are features of metabolic syndrome associated with decreased restorative sleep increased pain. These traits relevant for anesthesiology because they confer risks a negative anesthetic outcome. This study tested the one-tailed hypothesis that rats bred low intrinsic aerobic capacity have enhanced nociception disordered sleep. Methods Rats were developed from breeding strategy selected runners (LCR) high (HCR). Four phenotypes...
Telemedicine for preanesthesia evaluation can decrease access disparities by minimizing commuting, time off work, and lifestyle disruptions from frequent medical visits. We report our experience with the first 120 patients undergoing telemedicine at Moffitt Cancer Center.This is a retrospective analysis of seen via compared an in-person cohort meeting criteria had it been available. was conducted clinic to patient's remote location using video conferencing. Clinic were revised create tier...
Introduction Volatile and intravenous anesthetics may worsen oncologic outcomes in basic science animal models. These effects be related to suppressed innate adaptive immunity, decreased immunosurveillance, disrupted cellular signaling. We hypothesized that would promote lung tumor growth via altered immune function a murine model tested this using an immunological control group of immunodeficient mice. Methods Lewis carcinoma cells were injected tail vein into C57BL/6 immunocompetent NSG...
The surgical stress and inflammatory response volatile anesthetic agents have been shown to promote tumor metastasis in animal in-vitro studies. Regional neuraxial anesthesia protects against these effects by decreasing the associated changes immune function animals. However, evidence of a similar effect humans remains equivocal due high variability retrospective nature clinical studies difficulty directly comparing regional versus general humans. We propose theoretical framework address...
Abstract Ventilator shortages during the COVID-19 pandemic forced some hospitals to practice and many consider shared ventilation, where a single ventilator is used ventilate multiple patients simultaneously. However, high risk of harm co-ventilated secondary inability treat anatomically different or safely adapt dynamic ventilation requirements has prevented full adoption multi-patient coventilation. Here, time-multiplexing approach introduced overcome these safety concerns. A...
Accurate quantification of intraoperative blood loss is crucial for enhancing patient safety and the success rate surgeries. Traditional estimation techniques, mainly reliant on visual assessments, are prone to significant inaccuracies due their subjective nature. This study introduces MDCare, an innovative deep learning-integrated system designed substantially improve precision using surgical sponges. By integrating advanced hardware components, including a mass sensor webcam, with...
Bronchial artery embolization (BAE) is a well-established intervention for hemoptysis that requires airway management by trained anesthesiologist. The use of fluoroscopic guidance positioning double-lumen endotracheal tube (DLT) has been described in previous studies. case presented illustrates combined fluoroscopic- and bronchoscopic-guided approach DLT patient with active pulmonary hemorrhage causing obstruction views on bronchoscopy. This technique proved valuable situation marked high...
Low physical fitness and obesity are associated with chronic pain (J Pain 8: 430, 2007) the mechanisms underlying this link difficult to explore in humans. This study is testing susceptibility experimentally induced two rat strains developed by two‐way artificial selection on a treadmill contrast for both intrinsic (untrained) obesity. Experiments were performed using generation 19 LCR (n=3) HCR males. threshold was measured as paw withdrawal latency (PWL) nociceptive thermal stimulus an...
The erector spinae plane block (ESPB), a recent innovation in regional anesthesia, has been used for analgesia of the thorax and chest. case presented describes use an ESPB postoperatively rescue on elderly, opioid-naïve patient, who had severe postoperative pain after outpatient surgery at axillary sentinel lymph node biopsy site refractory to escalating IV opioid doses. was successful reducing patient’s 0/10, allowing patient be discharged home preventing costly hospital admission.
Abstract Background Epidural catheters are routinely placed for many surgical procedures and to treat various pain conditions. Known complications arising from epidural catheter equipment malfunction include pump failure, shearing, connector filter cracking, loss-of-resistance syringe malfunction. Practitioners need be aware of these potentially dangerous take measures mitigate the chances causing significant patient harm. We report on complete breakage an during bolus administration local...
Enhanced Recovery After Surgery (ERAS) protocols represent a new era in surgical care many different disciplines, including gynecologic surgery. ERAS focuses on optimizing patient health prior to surgery and decreasing the stress response during after This leads benefits such as shortened length of stay, decreased postsurgical complications, readmission rates for patients. narrative article summarizes current developed from leading institutions—including Society, Stockholm, Sweden, American...
In medicine, the search for a clear answer can at times be elusive. However, this does not necessarily preclude administration of intelligent and thoughtful therapeutic treatments. Here, we describe complicated emergent event severe hypotension near-arrest that occurred in operating room young, healthy woman undergoing outpatient thyroid surgery. We detail situation as it presented measures taken to rule out potential life-threatening diagnoses develop treatment plan. further evidence...