A5066906580- Heat shock proteins research
- Endoplasmic Reticulum Stress and Disease
- Enzyme Structure and Function
- Protein Structure and Dynamics
- Cardiomyopathy and Myosin Studies
- Genetic Neurodegenerative Diseases
University of Oxford
2021-2024
Abstract The biomechanical properties and responses of tissues underpin a variety physiological functions pathologies. In striated muscle, the actin-binding protein filamin C (FLNC) is key whose variants causative for wide range cardiomyopathies musculoskeletal Seemingly multi-functional that interacts with partners, how FLNC regulated at molecular level not well understood. Here we have investigated its interaction HSPB7, cardiac-specific chaperone absence embryonically lethal. We found...
The Fourth Cell Stress Society International workshop on small heat shock proteins (sHSPs), a follow-up to successful workshops held in 2014, 2016 and 2018, took place as virtual meeting the 17-18 November 2022. was designed provide an opportunity for those working sHSPs reconnect discuss their latest work. diversity of research sHSP field is reflected breadth topics covered talks presented at this meeting. Here we summarise presentations some perspectives exciting future be addressed field.