John L. Falcone

ORCID: 0000-0002-6420-3582
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About
Contact & Profiles
Research Areas
  • Diversity and Career in Medicine
  • Innovations in Medical Education
  • Surgical Simulation and Training
  • Hospital Admissions and Outcomes
  • Medical Education and Admissions
  • Cardiac, Anesthesia and Surgical Outcomes
  • Global Health Workforce Issues
  • Health and Medical Research Impacts
  • Healthcare Operations and Scheduling Optimization
  • Augmented Reality Applications
  • Anatomy and Medical Technology
  • Literature, Magical Realism, García Márquez
  • Theater, Performance, and Music History
  • Simulation-Based Education in Healthcare
  • Radiology practices and education
  • Renal Transplantation Outcomes and Treatments
  • Clinical Reasoning and Diagnostic Skills
  • Trauma and Emergency Care Studies
  • Sleep and Work-Related Fatigue
  • Organ Transplantation Techniques and Outcomes
  • Patient Safety and Medication Errors
  • Neurofibromatosis and Schwannoma Cases
  • Themes in Literature Analysis
  • American and British Literature Analysis
  • Shakespeare, Adaptation, and Literary Criticism

Owensboro Health
2015-2024

University of Louisville
2014-2023

Geisinger Medical Center
2021

King's College London
2019

Virginia Mason Medical Center
2019

Cornell University
2004-2018

KentuckyOne Health
2017

University of Pittsburgh
2006-2016

University of Louisville Hospital
2016

University of Pennsylvania
2015

Abstract Context Radioactive iodine (RAI) has been epidemiologically associated with the development of hematologic malignancies. Clonal hematopoiesis (CH) is a precursor clonal state that confers increased risk leukemia and occurs at an elevated rate in patients thyroid cancer relative to other solid tumors. Objective We explore if high prevalence CH may be result RAI exposure whether surrogate association between leukemia. Design CH, CH-potential driver (CH-PD), overall survival were...

10.1210/jc.2018-00803 article EN The Journal of Clinical Endocrinology & Metabolism 2018-08-17

A poly(lactic-co-glycolic acid) (PLGA) microsphere formulation was developed which incorporates carboxylic acid groups into the surface. These functional are suitable for coupling to a variety of ligands and form linkages that remain stable in aqueous environments extended periods time. The ligand binding capacity these microspheres compares favorably similarly sized carboxylated polystyrene microspheres, commonly used as model particles targeted delivery studies. Targeting specific cell...

10.1021/ma049470u article EN Macromolecules 2004-11-20

Autophagy is a highly conserved mechanism that activated during cellular stress. We hypothesized autophagy may be induced by acid reflux, which causes injury, and inflammation, therefore, contributes to the pathogenesis of Barrett's esophagus (BE) esophageal adenocarcinoma (EAC). Currently, role in BE EAC poorly studied. quantitatively define levels human cell lines, transgenic mouse model BE, biopsies. Human non‐dysplastic had highest basal number autophagic vesicles (AVs), while AVs were...

10.1002/mc.22406 article EN Molecular Carcinogenesis 2015-09-16

Neurofibromatosis type 1 (NF-1) is an autosomal dominant disease primarily characterized by cutaneous café au lait macules, benign neurofibromas, and iris hamartomas. A spectrum of vascular abnormalities associated with NF-1. We present a case 49-year-old female NF-1 spontaneous rupture the infrarenal aorta caused invasion neurofibroma treated endovascular stent grafting.

10.1177/1538574409345033 article EN Vascular and Endovascular Surgery 2009-10-14

Objective. To describe residency program compliance to a 60% pass rate and 80% eligibility standard outlined by the Accreditation Council for Graduate Medical Education (ACGME) on American Board of Pediatrics Certifying Examination. The hypothesis is that larger programs will have higher rates. Methods. Pediatric were retrospectively evaluated from 2008 2010 regarding ACGME standards. Simple linear regression was performed see if rates dependent size. Results. A total 162/163 (83.4%) had...

10.1177/0009922812436550 article EN Clinical Pediatrics 2012-02-13

<h3>Background:</h3> The Accreditation Council for Graduate Medical Education (ACGME) sets residency performance standards the American Board of Family Medicine Certification Examination. This study aims are to describe compliance programs with ACGME and determine whether pass rates depend on program size location. <h3>Methods:</h3> In this retrospective cohort study, from 2007 2011 was compared standards. Simple linear regression performed see were dependent size. Regional differences in...

10.3122/jabfm.2013.04.120307 article EN public-domain The Journal of the American Board of Family Medicine 2013-07-01

To determine Internal Medicine residency program compliance with the Accreditation Council for Graduate Medical Education 80% pass-rate standard and correlation between size performance on American Board of Certifying Examination.Using a cross-sectional study design from 2010-2012 Examination data all pro-grams, comparisons were made pass rates to standard. assess performance, Spearman's rho was calculated. evaluate its relationship standard, receiver operative characteristic curves...

10.5116/ijme.52c5.6602 article EN cc-by International Journal of Medical Education 2014-01-18

Duty hour limitations initiated by the Accreditation Council for Graduate Medical Education (ACGME) in 2003 could improve resident education surgical specialties.The purpose of this study was to evaluate national board examination performance and its relationship ACGME duty standards.In retrospective cohort study, electronically published website content evaluated statistics 10 boards American Board Specialties. To trends over time, we performed simple linear regression. We also interrupted...

10.4300/jgme-d-12-00106.1 article EN Journal of Graduate Medical Education 2013-07-10

Performance on the American Board of Family Medicine (ABFM) Certification and Recertification Examinations by country medical school training has not been examined. Based internal medicine patterns, we hypothesize that examinees trained in United States Canada would outperform other countries.In this retrospective cohort study from 2004 to 2011, data ABFM examinations were obtained ABFM. Fisher exact χ(2) tests performed across years based examinee training. Simple linear regression was...

10.3122/jabfm.2013.01.120207 article EN The Journal of the American Board of Family Medicine 2013-01-01
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