- Bipolar Disorder and Treatment
- Treatment of Major Depression
- Electroconvulsive Therapy Studies
- Mental Health Treatment and Access
- Attention Deficit Hyperactivity Disorder
- Health, psychology, and well-being
- Child and Adolescent Psychosocial and Emotional Development
- Tryptophan and brain disorders
- Health Promotion and Cardiovascular Prevention
- Maternal Mental Health During Pregnancy and Postpartum
- Stress Responses and Cortisol
- Genetics and Neurodevelopmental Disorders
- Adolescent and Pediatric Healthcare
- Empathy and Medical Education
- Obsessive-Compulsive Spectrum Disorders
- Psychiatric care and mental health services
- Neuroethics, Human Enhancement, Biomedical Innovations
- Healthcare Decision-Making and Restraints
- Psychopathy, Forensic Psychiatry, Sexual Offending
- Neurotransmitter Receptor Influence on Behavior
- Health and Medical Research Impacts
- Innovations in Medical Education
- Schizophrenia research and treatment
Loyola University Chicago
2021
Tufts Medical Center
2011-2015
Tufts University
2012-2015
McLean Hospital
2015
Massachusetts General Hospital
2015
University Medical Center
2012-2015
Objective To examine the efficacy of ziprasidone vs. placebo for depressive mixed state in patients with bipolar disorder type II or major (MDD). Methods 73 were randomized a double-blinded, placebo-controlled study to (40-160 mg/d) 6 weeks. They met DSM-IV criteria episode (MDE), while also meeting 2 3 (but not more nor less) manic criteria. did meet episode. Baseline psychotropic drugs continued unchanged. The primary endpoint measured was Montgomery- Åsberg Depression Rating Scale (MADRS)...
To assess the efficacy and safety of citalopram in acute maintenance phases bipolar depression a randomized, double-blind, placebo-controlled trial.Between 2007 2014, 119 subjects with major depressive episodes diagnosed DSM-IV disorder, type I or II, were randomized blindly to placebo, added standard mood stabilizers. They followed for 6 weeks (primary outcome) up 1 year (secondary using scores on Montgomery-Asberg Depression Rating Scale (MADRS) Mania Schedule Affective Disorders...
Objectives Although efficacious treatments for mood disorders are available in primary care, under-diagnosis is associated with under-treatment and poorer outcomes. This study compares the accuracy of self-administered screening tests routine general practitioner (GP) assessment detection current disorder. Methods 197 consecutive patients attending care centres Santiago, Chile enrolled this cross-sectional study, filling out Patients Health Questionnaire-9 (PHQ-9) depression Mood Disorder...
We sought to test the hypothesis that antidepressants (ADs) may show preferential efficacy and safety among patients with type II bipolar disorder (BD, BD-II) more than I BD (BD-I).Patients Diagnostic Statistical Manual of Mental Disorders, Fourth Edition, BD-I (n = 21) BD-II 49) in acute major depressive episodes were treated ADs plus mood stabilizers euthymia sustained for 2 months then randomized openly continue or discontinue up 3 years. Outcomes episode recurrences changes standardized...
This review examines the diagnostic validity of adult ADHD on basis phenomenology, genetics, course illness and treatment response in context a hierarchy. In addition, it options, particularly amphetamine use, associated risks clinical social factors that may influence treatment. Risks neurotoxicity with amphetamines are discussed.