- Health, Nursing, Elderly Care
- Dementia and Cognitive Impairment Research
- Cholinesterase and Neurodegenerative Diseases
- Public Health in Brazil
- Health Education and Validation
- Blood Pressure and Hypertension Studies
- Psychology and Mental Health
- Cognitive Functions and Memory
- Nerve injury and regeneration
- Pneumonia and Respiratory Infections
- Myasthenia Gravis and Thymoma
- Helicobacter pylori-related gastroenterology studies
- Schizophrenia research and treatment
- Cystic Fibrosis Research Advances
- Frailty in Older Adults
- Sexual function and dysfunction studies
- Microscopic Colitis
- Inflammatory Bowel Disease
- Physical Education and Gymnastics
- Respiratory Support and Mechanisms
- Autoimmune Neurological Disorders and Treatments
- Parkinson's Disease and Spinal Disorders
- Epilepsy research and treatment
- Occupational Health and Burnout
- Herpesvirus Infections and Treatments
Universidade Federal de Minas Gerais
2011-2024
ORCID
2019
Hospital Bandeirantes
2016
Hospital das Clínicas da Universidade Federal de Minas Gerais
2014
University of Miami
2013
Background: Naturalistic studies evaluate individuals in their usual way of living, presenting more "real-life" data regarding patients and diseases. Objective: To investigate demographic, clinical, genetic factors that could be predictive
The clinical response to donepezil in patients with mild and moderate dementia was investigated relation the drug plasma concentration APOE CYP2D6 polymorphisms. In a prospective naturalistic observational study, 42 Alzheimer's disease (AD) AD cerebrovascular di sease who took (10 mg) for 12 months were evaluated. Their DNA genotyped, concentrations measured after 3, 6, months. Good responders scored ≥–1 on Mini-Mental State Examination at comparison baseline score. study results indicated...
Alzheimer's disease (AD) is characterized by impairment in memory and autonomy, causing excessive pressure on family an overburdened health care system. Early diagnosis, with the appropriate treatment, important to reduce pattern of progression.The study sought identify most probable causes delay diagnosis.A cross-sectional involving AD patients followed at Outpatient Geriatric Clinic from a tertiary public university hospital was conducted between June 2009 February 2011.Ninety-four were...
ABSTRACT. There are different causes of memory complaints in the elderly, such as subjective cognitive decline (SCD), mild impairment (MCI) or dementia. Objective: 1) To characterize individuals with a mid-sized city Brazil, through clinical, and functional assessment; 2) to compare SCD MCI dementia patients terms clinical variables. Methods: We consecutively included aged ≥50 years, (spontaneous inquired). Subjects who scored ≥25 on Memory Complaint Questionnaire had spontaneous were...
OBJETIVOS: Comparar aspectos clínicos, radiológicos e evolutivos de idosos internados com diagnóstico clínico pneumonia comunitária, ou sem confirmação radiológica. MÉTODOS: Foram estudados, retrospectivamente, 141 pacientes idade acima 60 anos. RESULTADOS: Em 45 pacientes, os achados corroboraram o e, em 96 a radiologia não foi compatível suspeita clínica. Os sinais, sintomas, terapêutica desfechos destes dois grupos foram comparados. do estudo sugerem que houve diferença significativa...
RESUMO Objetivo Trata-se de um estudo descritivo, dividido em duas abordagens distintas, a respeito do trabalho voluntário entre estudantes Medicina. Este artigo buscou compreender o nível engajamento desses projetos voluntários e as repercussões geradas com atuação projeto voluntariado da Universidade Federal Minas Gerais (UFMG) grupo alunos. Método O foi realizado partes. A primeira parte trata-se transversal análise quantitativa que, por meio questionário online na plataforma Google...
Life expectancy in Brazil has increased markedly over the last 30 years. Hence, age-related disorders, such as Alzheimer's disease (AD), warrant special attention due to their high prevalence elderly. Pharmacologic treatment of AD is based on cholinesterase inhibitors (ChEI) and memantine, leading modest clinical benefits both short long-term. However, response heterogeneous needs further investigation.To investigate rate ChEI after three months treatment.Patients with mild or moderate...
Abstract Background Memory complaints are frequent in older adults and associated with higher risk of cognitive decline. Objective To investigate the functional outcome individuals memory followed up at primary care centers. Methods Data were collected between 2016 e 2020 health centers Brazil. Patients underwent Brief Cognitive Screening Battery, Functional Activities Questionnaire. Results The initial sample (2016) comprised 91 classified into those subjective decline (SCD, n = 15), mild...
OBJETIVO: Avaliar a adesão ao tratamento medicamentoso e possíveis fatores associados em idosos entrevistados durante consultas realizadas Unidades Básicas de Saúde. MÉTODO: Trata-se um estudo transversal, base populacional, com amostra 57 pacientes idade entre 60 99 anos, residentes do município Ponto dos Volantes, Minas Gerais, incluindo as zonas rural urbana. A coleta dados se deu o ato da consulta médica, através roteiro eletrônico estruturado. associação os parâmetros nível foi avaliada...
Objetivo: Relatar um caso de Herpes zoster (HZ) seguido por paresia do segmentar, uma complicação relacionada ao comprometimento da raiz e dano axonal, discutir suas estratégias gestão prevenção. Detalhamento Caso: Paciente 80 anos, masculino, hipertenso, pré-diabético portador doença pulmonar obstrutiva crônica (DPOC), compareceu à consulta com queixa dor nas pernas esquerda no quadril, sem outros sintomas. Suspeitou-se artrose quadril joelhos, mas esse evoluiu dia seguinte lesões...
OBJETIVOS: Investigar os fatores demográficos, clínicos e genéticos que poderiam ser preditivos de boa resposta ao tratamento com inibidores da colinesterase (IChE) na doença Alzheimer (DA) demência mista; medir a concentração plasmática donepezila (CPD) em pacientes uso medicação; verificar correlação entre CPD polimorfismos do gene Apoliproteína E (APOE) CYP2D6, bem como clínica. MÉTODOS: Estudo naturalístico, compareceram ambulatório Geriatria Neurologia Hospital das Clínicas Faculdade...
Objetivo: Relatar um caso de Demência Frontotemporal (DFT) variante comportamental que, não raro, é erroneamente diagnosticado e tratado como Doença Alzheimer (DA). Detalhamento do caso: Trata-se uma paciente 65 anos, a qual iniciou quadro demencial em 2019, manifestado por amnésia, irritabilidade perda funcionalidade associadas à mudança repentina hábitos vida (retomou o hábito etilismo obstinação/dependência amorosa). À nossa primeira avaliação 2021, apresentava diagnóstico prévio DA...
Objective: To present a favorable outcome in Myasthenia gravis (MG) patient with myasthenic crisis and discuss its main diagnostic challenges. Case detail: We report the case of previously healthy 80-year-old male who first presented dysphagia that quickly progressed to generalized syndrome leading ICU admission intubation over course less than two months. He was investigated firstly for thymoma, followed by Parkinson’s disease Lambert-Eaton before closing on MG. successfully stabilized...
Objective: To report a case of trigeminal neuralgia observed in 52-year-old patient who had pre-diabetes and hypertension, fibromyalgia as previous comorbidities, surgical history carpal tunnel syndrome correction. Case details: On September 30, 2022, the reported intense right-sided unilateral headache. The was on Metformin, Hydrochlorothiazide (HCTZ), Losartan. For treatment possible neuralgia, Carbamazepine initially prescribed at dose 200 mg every 12 hours later adjusted to 8 hours. It...
Background:The knowledge of the epidemiological profile elderly population in areas high socioeconomic vulnerability is essential for diagnosis and efficacy care.Objective: This article aims to identify priorities future interventions small communities through one day evaluation several measures elderly, such as blood pressure, capillary glycemia, Mini Mental State Examination (MMSE), calf circumference "get up go" test, obtain these patients' risk falling.From this, we intend suggest a...
The aims of this work are to verify the prevalence main comorbidities population in city Ponto dos Volantes, Minas Gerais; assess patients knowledge degree relation their diseases; association between comorbidities, schooling, socioeconomic level and adherence treatment; foster volunteering UFMG medical students. Eighty-seven patients, males females, were selected from elderly adults Volantes. data collection was done by students Faculty Medicine UFMG, allocated outpatient clinics urban...
Background: Evidence from longitudinal studies points to the syndromic continuum of dementia. Individuals with mild cognitive impairment (MCI) are at increased risk progressing dementia over time, as well older adults subjective decline (SCD). Objective: To assess impact treating reversible causes on outcome patients decline. Methods: Data were collected between 2017 and 2020 (mean follow-up = 44.52 ±6.85 months) in primary health care Patos de Minas, MG. Subjects screened using MMSE, Figure...