A5052615746- Asthma and respiratory diseases
- Inflammatory Biomarkers in Disease Prognosis
- Pancreatic and Hepatic Oncology Research
- IL-33, ST2, and ILC Pathways
- Neonatal Respiratory Health Research
- Neuroendocrine Tumor Research Advances
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory and Cough-Related Research
- Aortic aneurysm repair treatments
- Genetic factors in colorectal cancer
- Circular RNAs in diseases
- Diabetes and associated disorders
- Orthopedic Surgery and Rehabilitation
- Aortic Disease and Treatment Approaches
- Parathyroid Disorders and Treatments
- Infectious Aortic and Vascular Conditions
- Pancreatic function and diabetes
- Platelet Disorders and Treatments
- Colorectal and Anal Carcinomas
- Intraperitoneal and Appendiceal Malignancies
- Cancer Cells and Metastasis
- Vasculitis and related conditions
- Renal Transplantation Outcomes and Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- TGF-β signaling in diseases
Medical University of Lodz
2021-2025
Background/Objectives: Acute ankle sprains are common injuries that significantly affect both sports and daily activities. Syndesmotic injuries, a specific type of ligamentous damage, can occur as part sprain or alongside fractures, affecting approximately 20% fractures. The aim this study was to evaluate negative prognostic factors influencing surgical outcomes in tibiofibular syndesmotic associated with Methods: Data from 246 patients were analyzed examine the impact initial dislocation,...
AMA Koćwin M, Jonakowski Majos A, Szemraj J, Kuna P, Panek M. Evaluation of serum levels all the transforming growth factor β (TGF-β 1-3) isoforms in asthmatic patients. Alergologia Polska - Polish Journal Allergology. 2024. doi:10.5114/pja.2024.138449. APA Koćwin, M., Jonakowski, Majos, A., Szemraj, J., Kuna, P., & Panek, (2024). https://doi.org/10.5114/pja.2024.138449 Chicago Marcelina, Mateusz Alicja Janusz Piotr and Michał Panek. "Evaluation patients". Harvard MLA Marcelina et al....
(1) Background: The importance of total eosinophil count in peripheral blood (EOS) as a type 2 inflammation marker is known to be fundamental asthma, chronic sinusitis, and vasculitis. In cancer, despite their questionable antiproliferative effect, role remains unclear. Our purpose was describe the relationship between baseline EOS overall survival (OS) pancreatic ductal adenocarcinoma (PDAC) patients. (2) Methods: We retrospectively analyzed data from 137 adult patients who underwent...
Background: MicroRNAs (miRNAs) are small RNA molecules involved in the control of expression many genes and responsible for, among other things, cell death, differentiation their division. Changes miRNA profiles have been observed colorectal cancer. This discovery significantly enriches our knowledge pathogenesis cancer offers new goals diagnostics therapy. Aim: The aim this study was to analyze four sequences—miR-143, miR-1, miR-210 let-7e—and investigate significance risk developing...
Preclinical evidence suggests that T4 can promote tumor growth while T3 act conversely; therefore, the fT3 and fT4 concentrations should affect overall survival (OS) in cancer patients. The objective of study was to look for an association between thyroid hormone peripheral blood OS pancreatic adenocarcinoma (PDAC) patients group. We included, retrospectively, 15 PDAC patients, without dysfunction under treatment, who underwent radical surgery, with no prior history anticancer therapy. TSH,...
A ruptured abdominal aortic aneurysm is a severe condition associated with high mortality. Currently, the most important criterion used to estimate risk of its rupture size aneurysm, but due patients' anatomical variability, many aneurysms have small size. We asked ourselves whether individual differences in anatomy could be taken into account when assessing rupture.Based on CT scan image, and normal aorta diameters were collected from 186 individuals compared patients unruptured aneurysms....
Primary gastric squamous cell carcinoma (GSCC) is an extremely rare malignancy with a poor prognosis. Despite the improved knowledge regarding its pathogenesis and biology, treatment options remain limited. The present study reported on unique case of mismatch repair‑deficient (dMMR) primary GSCC in 79‑year‑old woman reporting fatigue symptoms upper gastrointestinal tract bleeding. Physical examination revealed abdominal pain at palpation. Gastroscopy large, exophytic, bleeding tumor....
Abstract Introduction: The Transforming Growth Factor β (TGF-β) has attracted particular attention from researchers in the context of pathogenesis and development asthma allergic diseases. Undoubtedly, TGF-β is one main cytokines involved mediating inflammation bronchial remodeling. It stimulates fibroblasts myofibroblasts, regulates processes extracellular matrix remodeling, thus contributing to fibrosis In long-term inflammation, airways become stiffened airflow impaired, which sometimes...
AMA Koćwin M, Jonakowski Majos A, Szemraj J, Kuna P, Panek M. Evaluation of TGF-β isoforms based on selected clinical parameters in asthmatic patients. Alergologia Polska - Polish Journal Allergology. 2024. doi:10.5114/pja.2024.138537. APA Koćwin, M., Jonakowski, Majos, A., Szemraj, J., Kuna, P., & Panek, (2024). https://doi.org/10.5114/pja.2024.138537 Chicago Marcelina, Mateusz Alicja Janusz Piotr and Michał Panek. "Evaluation patients". Harvard MLA Marcelina et al. patients." Allergology, Vancouver
Introduction Vascular complications are a rare but important risk factor for failure and loss of kidney graft, increasing the mortality renal graft recipients. Case report We present case massive haemorrhage due to rupture arterial anastomosis caused by <i>Candida albicans</i> infection in 64-year old female recipient managed with suprapubic iliofemoral bypass during emergency life-saving nephrectomy performed our unit. The postoperative period was complicated femoral vein...
(1) Background: Eosinophils importance as T2 inflammation markers is known to be fundamental in asthma, chronic sinusitis, vasculitis. In cancer, despite their potential antiproliferative effect, role remains unclear. Our purpose was describe the relation between baseline blood eosinophil count (EOS) and overall survival pancreatic ductal adenocarcinoma (PDAC) patients. (2) Methods: We have analyzed retrospectively data of 137 adult patients, who underwent surgical treatment PDAC years...
Asthma is characterized by chronic bronchial inflammation and a highly heterogeneous disease strongly influenced both specific non-specific exogenous factors. The present study was performed to assess the effect of nasal allergen provocation tests methacholine on mRNA co-expression patterns genes (
Objective: Pancreatic adenocarcinoma (PDAC) and mass forming chronic pancreatitis (CP) can be easily misdiagnosed due to their resemblances in clinical, radiological, biochemical criteria. In our previous study, we reported a very high concentration of D-Dimers portal blood patients with pancreatic cancer which may help differentiate malignant from benign tumours. this aim describe other peripheral coagulation profiles PDAC comparison CP patients, as well test the hypothesis; thus, it is...
Introduction. We aimed to assess the prognostic significance of preoperative absolute monocyte count (AMC) in baseline peripheral blood samples among pancreatic cancer (PC) patients as possible manifest signs non-optimal immunity status. Material and methods. PC who underwent palliative surgical treatment without earlier chemo- or radio-therapy (n = 59). Results. Median AMC was comparable each subgroup, showing no significant differences. have adopted an arbitrary trichotomic division: low...
<b>Background:</b> The Transforming Growth Factor β (TGF-β) is one of the main cytokines involved in mediating inflammation and bronchial remodeling.In long-term inflammation, airways become stiffened airflow impaired, which sometimes reflected by lower values spirometric parameters. What may also be observed aging organs are intensified fibrotic processes. <b>Aims:</b> aim study was to evaluate correlation between concentrations all TGF-β1-3 isoforms selected clinical parameters, including...
<b>Introduction:</b> Surgery remains the mainstay of treatment for liver tumors. Significant differences in complication rates between surgery centers have been reported ranging from 4.1% up to 47.7%. There little papers or studies on impact bile infection postoperative complications patients undergoing cancer. </br></br> <b>Aim:</b> The aim our study was assess etiology infections following resection and evaluate its perioperative mortality....
<br><b>Introduction:</b> Repair of type 2 and 3 hiatal hernias (paraesophageal mixed) remains technically challenging with a risk complications recurrence up to 40%. The use synthetic mesh is associated possible serious complications. However, the effectiveness biological materials unclear requires further research.</br> <br><b>Aim:</b> aim this study was present experience our clinic in management large using round ligament liver emphasize potential...