A5078677736- Sepsis Diagnosis and Treatment
- Bacterial Identification and Susceptibility Testing
- Pharmaceutical studies and practices
- Antibiotics Pharmacokinetics and Efficacy
- Antibiotic Use and Resistance
- Emergency and Acute Care Studies
- Vitamin K Research Studies
- Clinical Reasoning and Diagnostic Skills
- Cervical and Thoracic Myelopathy
- Spinal Fractures and Fixation Techniques
- Adrenal Hormones and Disorders
- Pneumocystis jirovecii pneumonia detection and treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Cervical Cancer and HPV Research
- Spinal Dysraphism and Malformations
- Schizophrenia research and treatment
- Anesthesia and Pain Management
- Helicobacter pylori-related gastroenterology studies
- Streptococcal Infections and Treatments
- Nosocomial Infections in ICU
- Clinical Laboratory Practices and Quality Control
- Hospital Admissions and Outcomes
- Trauma and Emergency Care Studies
- Spine and Intervertebral Disc Pathology
- Bipolar Disorder and Treatment
Geneeskundige en Gezondheidsdienst
2024
Vrije Universiteit Amsterdam
2019-2024
Amsterdam University Medical Centers
2019-2024
Amsterdam UMC Location Vrije Universiteit Amsterdam
2017-2022
General Department of Preventive Medicine
2018-2020
Albert Schweitzer Ziekenhuis
2017
Utrecht University
2011
Wilhelmina Children's Hospital
2008
University Medical Center Utrecht
2008
BackgroundOveruse of blood cultures (BCs) in emergency departments (EDs) leads to low yields and high numbers contaminated cultures, accompanied by increased diagnostics, antibiotic usage, prolonged hospitalization, mortality. We aimed simplify validate a recently developed machine learning model help safely withhold BC testing low-risk patients.MethodsWe extracted data from the electronic health records (EHR) for 44.123 unique ED visits with sampling Amsterdam UMC (locations VUMC AMC;...
To develop predictive models for blood culture (BC) outcomes in an emergency department (ED) setting.Retrospective observational study.ED of a large teaching hospital the Netherlands between 1 September 2018 and 24 June 2020.Adult patients from whom BCs were collected ED. Data demographic information, vital signs, administered medications ED laboratory radiology results extracted electronic health record, if available at end visits.The primary outcome was performance two (logistic regression...
Abstract Background In the Netherlands, home treatment with intravenous antimicrobial therapy is a relatively new concept. Although several studies have shown that outpatient parenteral (OPAT) can be administered safely, people receiving antimicrobials at remain risk for adverse events, including readmission. Aim The aim of our retrospective study was to identify factors readmission in patients discharged OPAT. Method Patients who were least 18 years or older, OPAT between January...
Evidence for an association between duration of untreated illness (DUI) with clinical and functional outcome or brain volume (change) in schizophrenia patients is inconclusive. We aimed to investigate the relationship DUI, at onset change during first five years first-episode patients.Magnetic resonance images were acquired baseline (T0) after 5-year (T5) 57 patients. Correlations calculated (change), DUI variables.We found no significant correlation A longer was significantly correlated...
Due to the rise in incidence, long term effect of sepsis are becoming more evident. There is increasing evidence that may result an impaired health related quality life. The aim this study was investigate whether life survivors and which clinical parameters associated with affected life.We analyzed 880 Short Form 36 (SF-36) questionnaires were sent who participated Prehospital Antibiotics Against Sepsis (PHANTASi) trial. These by email, 28 days after discharge. Data entry statistical...
During the winter, many patients present with suspected infection that could be a viral or bacterial (co)infection. The aim of this study is to investigate whether optimal use procalcitonin (PCT) different in and without proven infections for purpose excluding bacteremia. We hypothesize when confirmed, lowers probability bacteremia and, therefore, influences appropriate cutoff procalcitonin.This was conducted emergency department an academic medical center Netherlands winter seasons 2019...
Background and importance: Long waiting times in the emergency department (ED) is an increasing problem recent years expected to become even bigger future Objective: We aimed test hypothesis whether awareness of time lapse with treating physician, 2 hours after patient arrival, can reduce long turnaround (TAT). Method: In this prospective single-center cohort study we compared analyzed TAT ED before implementation a so called ‘traffic light’ moment arrival. At light” team member contacted...
Abstract Background: In the Netherlands, home treatment with intravenous antimicrobial therapy is a relatively new concept. Although several studies have shown that outpatient parenteral (OPAT) can be administered safely, people receiving antimicrobials at remain risk for adverse events, including readmission. Objectives: The aim of our retrospective study to identify factors readmission in patients discharged OPAT. Method: Retrospective cohort during period January 2016 - December 2018....