A5039104479- Acupuncture Treatment Research Studies
- Pain Mechanisms and Treatments
- Healthcare and Venom Research
- Myofascial pain diagnosis and treatment
- Vagus Nerve Stimulation Research
- Heart Rate Variability and Autonomic Control
- Gastrointestinal motility and disorders
- Pain Management and Placebo Effect
- Laser Applications in Dentistry and Medicine
- Psychosomatic Disorders and Their Treatments
- Traditional Chinese Medicine Studies
- Complementary and Alternative Medicine Studies
- Infant Health and Development
- Neuroscience and Neuropharmacology Research
- Dermatology and Skin Diseases
- Exercise and Physiological Responses
- Ion Channels and Receptors
- Neuropeptides and Animal Physiology
- Neuroscience of respiration and sleep
- Musculoskeletal pain and rehabilitation
- Pain Management and Treatment
- Biofield Effects and Biophysics
- Infrared Thermography in Medicine
- Synthesis and Biological Evaluation
- Pharmacological Effects and Toxicity Studies
Chinese Academy of Medical Sciences & Peking Union Medical College
2016-2025
Shaanxi University of Chinese Medicine
2020-2025
Chongqing University of Arts and Sciences
2022-2025
Inner Mongolia University
2024
China Association of Acupuncture-Moxibustion
2005-2024
China Academy of Chinese Medical Sciences
2011-2024
ShanghaiTech University
2024
Dalian Medical University
2024
Second Affiliated Hospital of Dalian Medical University
2024
Nanjing University of Chinese Medicine
2020-2024
The objective was to investigate the relationship of disease severity, health beliefs and medication adherence among HIV/AIDS patients. A survey administered 72 patients in three different stages (CDC clinical categories A, B, C). Multivariate analyses revealed that there were no significant differences patients' perceptions severity or benefits barriers for treatment across stages. However, most severely ill (in stage C) perceived a higher risk complications if they did not take their...
Acupuncture is a commonly used therapy for treating functional dyspepsia (FD), although the mechanism remains unclear. The objectives of this study were to investigate differences in cerebral glycometabolism changes evoked by acupuncture and sham explore possible correlations between brain responses clinical efficacy.In all, 72 FD patients randomly assigned receive either or treatment 4 weeks. Ten each group selected fluorine-18 fluorodeoxyglucose positron emission tomography computed scans...
Auricular acupuncture has been described in ancient China as well Egypt, Greece, and Rome. At the end of 1950s, ear was further developed by French physician Dr. Paul Nogier. The goal this study to develop a new system for acupressure (vibration stimulation) perform pilot investigations on possible acute effects vibration manual heart rate (HR), variability (HRV), pulse wave velocity (PWV), augmentation index (AIx) using noninvasive recording methods. Investigations were performed 14 healthy...
Abstract Mechanisms of visceral pain sensitization and referred somatic hypersensitivity remain unclear. We conducted calcium imaging in Pirt -GCaMP6s mice to gauge responses dorsal root ganglion (DRG) neurons stimulation vivo. Intracolonic instillation 2,4,6-trinitrobenzene sulfonic acid (TNBS) induced colonic inflammation increased the percentage L6 DRG that responded colorectal distension above controls at day 7. Colorectal did not activate L4 neurons. TNBS-treated exhibited more Evans...
Dorsal Root Ganglion (DRG) neurons serve as crucial nodes for pain signal transmission, and their excitability regulation plays a key role in various physiological pathological processes. Ion channels, central components modulating DRG neuron function, are involved biological processes such conduction, neural integration, plasticity. This paper systematically analyzes the structural characteristics, functional mechanisms, roles of different types ion channels neurons, including sodium...
The integration of additional modalities increases the susceptibility large vision-language models (LVLMs) to safety risks, such as jailbreak attacks, compared their language-only counterparts. While existing research primarily focuses on post-hoc alignment techniques, underlying mechanisms within LVLMs remain largely unexplored. In this work , we investigate whether inherently encode safety-relevant signals internal activations during inference. Our findings reveal that exhibit distinct...
Background: Referred pain frequently co-exists with visceral pain. However, the exact mechanism governing referred somatic hyperalgesia remains elusive. Methods: By injecting 20% acetic acid into stomach, we established a mouse model of gastric ulcer (GU). Hematoxylin and eosin (H&E) staining was used as evaluation criterion for model. Evan’s blue (EB) von Frey tests detected sensitized area. The DRG neurons distributed among spinal segments area were prepared biochemical...
Abstract Peptide-drug-conjugates (PDCs) are emerging as promising alternatives to antibody-drug-conjugates (ADCs) in oncology. PDCs, with their smaller size (<10 kDa), can offer improved tumor penetration. Additionally, PDCs potentially exhibit a better safety profile due shorter blood PK, absence of an Fc domain, and reduced immunogenicity. Furthermore, be entirely chemically synthesized, providing homogeneous chemical entity. Epidermal Growth Factor Receptor (EGFR) is key target...
To observe the effect of electroacupuncture (EA) on neuronal activity primary afferent dorsal root ganglion (DRG) caused by different mechanical stimuli such as brush, clamp [clamping hind paw or "Zusanli" (ST36) acupoint] stimulation at temperatures (43 ℃, 51 4 ℃), so to explore interaction between EA signals and DRG level. The strength threshold activated A fiber was determined electrophysiological technique. neurons were labeled intrathecal injection AAV9 virus, response observed recorded...
OBJECTIVE: To evaluate the accordance between three measures of self-reported medication adherence. METHODS: A survey was administered to HIV patients. The adherence included a four-item Morisky-type scale (Measure1) and two defining as percentage doses taken prescribed during past days (Measure2) or weeks (Measure3). RESULTS: For Measure1, 29.2% patients were categorized high 61.5% medium Measure2 Measure3, mean scores 93.6% 96.5%, respectively. Using 90% cutoff values, 78.5% 95.4%...
Abstract Introduction: Paclitaxel-induced peripheral neuropathy (PIPN) is a common dose-limiting side effect of this cancer treatment drug. Spinal cord stimulation (SCS) has demonstrated efficacy for attenuating some neuropathic pain conditions. Objective: We aim to examine the inhibitory SCS on development PIPN and changes gene expression in spinal male rats after SCS. Methods: examined whether traditional (50 Hz, 6–8 h/session daily 14 consecutive days) administered during paclitaxel (1.5...
To observe how acupuncture stimulation influences the visceral nociception in rat and to clarify interactions between or somatic input nociceptive inputs spinal dorsal horn. These will provide scientific base for illustrating mechanism of on pain.Experiments were performed Sprague-Dawley rats stimulus was generated by colorectal distention (CRD). Unit discharges from individual single neuron recorded extracellularly with glass-microelectrode L(1-3) Acupuncture applied at contralateral...
Abstract Background Previous studies have demonstrated the efficacy of somatic stimulation for patients with gastrointestinal motility disorders. However, little effort has been made to investigate effects acupuncture on colonic motility, particularly in pathological conditions. The precise mechanism employed regulation still remains unclear. Methods We assessed effect at heterotopic acupoints distal using a warm‐water‐filled manometric balloon inserted 5–6 cm into rectum anesthetized normal...
Important fruit traits were screened in a plant breeding program concerning newly domesticated crop Sweden of rose hips. The taxa Rosa dumalis subsp. coriifolia , R . rubiginosa and villosa mollis, collected from 23 localities Scandinavia, investigated for weight, percentage flesh, dry matter vitamin C content. coriifolia, mollis had significantly larger fruits higher flesh than rubiginosa. Analysis intraspecific variation showed that R. subsp was the most variable taxon, followed by whereas...