Xin Fan

ORCID: 0000-0002-6627-8940
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About
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Research Areas
  • Advanced Sensor and Energy Harvesting Materials
  • Cytomegalovirus and herpesvirus research
  • Immune Cell Function and Interaction
  • Conducting polymers and applications
  • Systemic Lupus Erythematosus Research
  • Nanoplatforms for cancer theranostics
  • Graphene and Nanomaterials Applications
  • Electrospun Nanofibers in Biomedical Applications
  • Polydiacetylene-based materials and applications
  • Advanced Nanomaterials in Catalysis
  • Viral Infections and Immunology Research
  • Carbon and Quantum Dots Applications
  • Spine and Intervertebral Disc Pathology
  • Osteoarthritis Treatment and Mechanisms
  • Graphene research and applications
  • Advanced Photocatalysis Techniques
  • Hydrogels: synthesis, properties, applications
  • Animal Virus Infections Studies
  • 3D Printing in Biomedical Research
  • MXene and MAX Phase Materials
  • Bone Metabolism and Diseases
  • interferon and immune responses
  • RNA Research and Splicing
  • Orthopaedic implants and arthroplasty
  • Drug Transport and Resistance Mechanisms

Chinese Academy of Sciences
2024

University of Chinese Academy of Sciences
2024

Ningbo Institute of Industrial Technology
2024

Tsinghua University
2024

Sichuan University
2007-2023

Freie Universität Berlin
2019-2022

Berlin Institute of Health at Charité - Universitätsmedizin Berlin
2021

Humboldt-Universität zu Berlin
2021

Xinqiao Hospital
2015-2021

Army Medical University
2015-2021

Abstract Recent emerged antibacterial agents provide enormous new possibilities to replace antibiotics in fighting bacterial infectious diseases. Although abundant types of nanoagents are developed for preventing pathogen colonization, however, rationally design nonchemotherapic, robust, and clinical‐adaptable with tunable trap killing activities remains a major challenge. Here, demonstration controlling the trap, ablation, release pathogenic bacteria via stimulus‐responsive regulatory...

10.1002/adfm.201705708 article EN Advanced Functional Materials 2018-04-03

Recently emerging graphene-based 2D nanoplatforms with multiple therapeutic modalities provide enormous opportunities to combat pathogenic bacterial infections. However, because these materials suffer from complicated synthesis, massive dosage requirements, and abundant nonlocalized heat, much more simplified, tunable, localized eradication approaches are urgently required. Herein, we report on the fabrication of metal–organic-framework (MOF)-derived carbon nanosheets (2D-CNs) phase-to-size...

10.1021/acs.nanolett.9b01400 article EN Nano Letters 2019-05-22

Conductive hydrogels are ideal for flexible sensors, but it is still a challenge to produce such with combined toughness, self-adhesion, self-healing, anti-freezing, moisturizing, and biocompatibility properties. Herein, inspired by natural skin, highly stretchable, strain-sensitive, multi-environmental stable collagen-based conductive organohydrogel was constructed using collagen (Col), acrylic acid, dialdehyde carboxymethyl cellulose, 1,3-propylene glycol, AlCl3. The resulting exhibited...

10.1021/acsami.2c21566 article EN ACS Applied Materials & Interfaces 2023-02-24

Flexible sensing devices (FSDs) fabricated using conductive hydrogels have attracted researchers' extensive enthusiasm in recent years due to their versatility. Considering the complexity of application environments, integration various functional characteristics (e.g., excellent mechanical, antibacterial, and antifreezing properties) is an important guarantee for FSDs stably perform applications different environments. Herein, we developed a multifunctional polyvinyl alcohol (PVA)...

10.1021/acsami.2c18441 article EN ACS Applied Materials & Interfaces 2022-12-23

Abstract E‐skins based on conductive hydrogels are regarded as ideal candidates for sensing application. However, limited by the constructed materials and strategies, current have poor mechanical properties, single function, unsatisfactory conductivity, which seriously hinder their development Herein, natural goatskin with hierarchical 3D network structure weaved collagen fibers is used substrate material construction of ultra‐tough hydrogel through a “top‐down” strategy, in acrylic acid...

10.1002/adfm.202304015 article EN Advanced Functional Materials 2023-06-24

Conductive hydrogel strain sensors have triggered extensive research interest in artificial intelligence, human motion detection, electronic skin, and other technical fields. However, it is still challenging work to prepare conductive hydrogels integrated with good biocompatibility, recyclability, self-healing, strong adhesion properties both air underwater. Herein, a novel, ultraexcellent adhesive, multifunctional gelatin composite was fabricated through simple rapid one-pot method which...

10.1021/acs.iecr.2c03253 article EN Industrial & Engineering Chemistry Research 2022-11-30

Conductive hydrogels have attracted tremendous interest in the construction of flexible strain sensors and triboelectric nanogenerators (TENGs) owing to their good stretchability adjustable properties. Nevertheless, how simultaneously achieve high transparency, self-healing, adhesion, antibacterial, anti-freezing, anti-drying, biocompatibility properties through a simple method remains challenge. Herein, transparent, freezing-tolerant, multifunctional organohydrogel (PAOAM-PDO) as electrode...

10.1021/acsami.3c08052 article EN ACS Applied Materials & Interfaces 2023-08-16

Hydrogel-based flexible sensors have attracted extensive attention of researchers due to their great application potential in soft robots, electronic skin, motion monitoring, and disease diagnosis. However, it is still a challenge for hydrogel-based be integrated with good mechanical performance, sensitivity, self-adhesion, fatigue resistance, antibacterial activity, recyclability. Here, novel supramolecular polyoxymethylene cross-linking agent (PCD-Fc-CHO) was designed synthesized by the...

10.1021/acs.iecr.1c04997 article EN Industrial & Engineering Chemistry Research 2022-03-02

Abstract The construction of biomass-based conductive hydrogel e-skins with high mechanical properties is the research hotspot and difficulty in field biomass materials. Traditional collagen-based hydrogels, constructed by typical “bottom–up” strategy, normally have incompatible problem between property collagen content, extraction often necessary. To solve these problems, inspired content animal skins, this work proposed a “top–down” which was unnecessary skin skeleton (SCS) 3D network...

10.1186/s42825-023-00123-9 article EN cc-by Deleted Journal 2023-05-31

Abstract Severe infectious diseases caused by pathogenic bacteria have become urgent threats to global public health. Antibacterial materials with combined chemo‐photothermal therapeutic capabilities possess distinct advantages when compared many other antibacterial approaches. However, developing simplified and chemically tunable precursors synthesize such nanoagents for rapidly, safely, synergistically combating remains a huge challenge. Herein, metal–organic framework (MOF)‐derived...

10.1002/adfm.201900143 article EN Advanced Functional Materials 2019-05-27

Pathogenic bacterial infection has been becoming a global threat toward people's health, especially the massive usage of antibiotics due to lack antibacterial agents with less side effects. Developing new nanoagents fight pathogenic bacteria provided enormous possibilities in treatment infections, such as graphene-based two-dimensional (2D) different inhibition capabilities; however, mussel-inspired design near-infrared (NIR)-responsive and biocompatible Ag-graphene possessing efficient...

10.1021/acsami.7b16283 article EN ACS Applied Materials & Interfaces 2017-12-13

Abstract To overcome the ever-growing organic pollutions in water system, abundant efforts have been dedicated to fabricating efficient Fenton-like carbon catalysts. However, rational design of catalysts with high intrinsic activity remains a long-term goal. Herein, we report new N -molecule-assisted self-catalytic carbonization process augmenting metal–organic-framework-derived hybrids. During carbonization, -molecules provide alkane/ammonia gases and formed iron nanocrystals act as situ...

10.1007/s40820-019-0319-4 article EN cc-by Nano-Micro Letters 2019-10-17

Abstract Novel bionanocatalysts have opened a new era in fighting multidrug‐resistant (MDR) bacteria. They can kill bacteria by elevating the level of reactive oxygen species (ROS) presence chemicals like H 2 O . However, ROSs’ ultrashort diffusion distance limit their bactericidal activity. We present nanohook‐equipped bionanocatalyst (Ni@Co‐NC) with bacterial binding ability that shows robust ROS‐generating capacity under physiological levels. The Ni@Co‐NC's pH‐dependent performance...

10.1002/anie.202113833 article EN Angewandte Chemie International Edition 2021-11-26
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