A5029877822- Platelet Disorders and Treatments
- Lymphoma Diagnosis and Treatment
- Hemophilia Treatment and Research
- Multiple Myeloma Research and Treatments
- Chronic Lymphocytic Leukemia Research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Acute Myeloid Leukemia Research
- Chronic Myeloid Leukemia Treatments
- Hemoglobinopathies and Related Disorders
- Acute Lymphoblastic Leukemia research
- Viral Infections and Vectors
- Vector-borne infectious diseases
- Abdominal Trauma and Injuries
- Blood groups and transfusion
- Mosquito-borne diseases and control
- Complement system in diseases
- Hematological disorders and diagnostics
- Hematopoietic Stem Cell Transplantation
- Immunodeficiency and Autoimmune Disorders
- Renal Diseases and Glomerulopathies
- Blood Coagulation and Thrombosis Mechanisms
- Parvovirus B19 Infection Studies
- T-cell and Retrovirus Studies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
Sanjay Gandhi Post Graduate Institute of Medical Sciences
2014-2025
Franciscan Health
2024
Maharishi Markandeshwar University, Mullana
2021
Indira Gandhi Medical College
2013-2019
Kalpana Chawla Government Medical College and Hospital
2012
All India Institute of Medical Sciences
1996-2008
Abstract Himachal Pradesh state of India is situated in the outer Himalayan ranges. During rainy season, several cases acute febrile illness unknown origin occurred. Orientia tsutsugamushi was identified as causative agent by microimmunofluorescence and PCR. Two new genotypes O. were region.
ABSTRACT Objective The modern treatment protocols in B‐cell precursor acute lymphoblastic leukemia (BCP‐ALL) are based on the disease's genetic characteristics and response to treatment. We propose a novel five‐probe FISH strategy risk stratify BCP‐ALL compare its ability with triple trisomy probe detect high hyperdiploidy. Methods All newly diagnosed cases were investigated using panel that included probes targeting BCR::ABL1 fusion, ETV6::RUNX1 break‐apart for KMT2A , IgH CRLF2...
Summary. In order to define the prevalence of haemostatic defects in women presenting with menorrhagia our region, coagulation data on bleeders investigated Department Haematology, AIIMS, were analysed. A total 337 2200 menorrhagic characterized have an inherited bleeding disorder; 221 these presented alone while 116 also had other associated manifestations as prolonged from injury site, ecchymotic patches skin, epistaxis, haematomas, haemarthroses and major bleeds like intracerebral...
Abstract Aim: To study the maternal and fetal outcome in cases of aplastic anemia associated with pregnancy. Methods: Retrospective analysis seven diagnosed during Result: Four patients had an overall successful pregnancy outcome. These were all non‐severe anemia. There was one case each intrauterine neonatal death severe group. mortality. Conclusion: Maternal is poor
Cranial nerve involvement in multiple myeloma and solitary plasmacytoma is rare. We report on two patients who developed cranial palsy due to skull base plasmacytoma. Patient 1, a 55-year old man with myeloma, right sixth during phase of chemotherapy. He had an intracranial the clival region was treated 30 Gy whole brain radiotherapy. 2, 40-year man, presented third detected have radiotherapy followed by thalidomide plus dexamethasone.
Autoimmune hemolytic anemia (AIHA) is frequently associated with B-cell lymphoproliferative disorders, and patients rarely develop overt clinical manifestations of AIHA. AIHA rare in multiple myeloma (MM). We conducted a prospective study to detect the presence MM its impact on presentation outcome disease.Sixty-six were diagnosed have MM. Seventeen these who had severe (hemoglobin < 6 g/dL) requiring frequent blood transfusions or without features hemolysis screened for by performing direct...
Postpartum acquired haemophilia is a rare but serious complication of an otherwise normal pregnancy. Patients usually present with postpartum haemorrhage (PPH) or uncontrolled bleeding following surgical interventions, which fail to respond conservative treatment. A high index clinical suspicion along early laboratory diagnosis and prompt institution appropriate therapy essential for the management acute episodes. Our patient, 32‐year‐old female, presented severe PPH shock. She had undergone...
Abstract Glanzmann's thrombasthenia is an autosomal recessive, inherited platelet function disorder. There absence of glycoprotein (GP) IIb/IIIa on the membrane which causes reduced aggregation with a defective haemostatic plug formation. The management bleeding episodes in these patients transfusions may result alloimmunization and make successive less effective. Pregnancy delivery rare associated high risk severe haemorrhage. We describe primigravida who developed secondary postpartum...
Despite extensive work-up to establish the cause of splenomegaly, splenectomy may be required for diagnosis in certain situations. The aim this study was find out role diagnostic current era.Between January 1989 and June 2004, 211 patients underwent indications other than trauma. In 41 (19%) patients, carried purposes. Retrospective analysis these done purpose study.All who had a complete haemogram, biochemical tests liver renal function, bone marrow biopsy abdominal ultrasonography before...
Summary. A 25‐year‐old male with severe haemophilia developed deep vein thrombosis of the left upper limb. Venography showed basilic vein. There was no underlying prothrombotic condition. He successfully treated low‐molecular weight heparin.
Autoimmune hemolytic anemia (AIHA) associated with giant cell hepatitis (GCH) is a rare disorder in infants. AIHA usually precedes the development of liver disease by months to years. Early recognition and prompt institution immunosuppressive therapy results clinical remission prevents progression. Am. J. Hematol. 81:199–201, 2006. © 2006 Wiley-Liss, Inc.
Abstract Introduction Leukemic stem cells (LSCs) are the transcriptionally low/silent which resistant to tyrosine kinase inhibitor. These have been found play a pivotal role in disease relapse chronic myeloid leukemia (CML) cases. The present study evaluated correlation of absolute CML‐LSC count peripheral blood (PB) at diagnosis and achievement major molecular response (MMR) 12 months patients CML‐CP. Methods This was prospective, observational, non‐interventional single center including...
Background: Atrial fibrillation (AF) is the most common sustained arrhythmia in clinical practice. In western countries, rheumatic heart disease (RHD) a rare cause of atrial but developing countries like India it one commonest fibrillation. We studied etiology, left size and incidence appendage clot patients with at our institution so that guidelines could be formulated to manage AF hours emergency.Methods: 110 consecutive coming emergency, cardiology medicine outpatient department over...
Summary Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired clonal stem cell disorder with altered expression of glycosylphosphatidylinositol (GPI)‐anchored proteins, resulting in the increased susceptibility erythrocytes to complement‐mediated lysis. This study compared available laboratory methods for detection PNH cells and evaluated their utility routine clinical practice. Fifty patients were by flow cytometric immunophenotyping (FCMI) using CD55 CD59 monoclonal antibodies, gel card...