A5006209264- Neurotransmitter Receptor Influence on Behavior
- Receptor Mechanisms and Signaling
- Neuroscience and Neuropharmacology Research
- Neuroendocrine regulation and behavior
- Memory and Neural Mechanisms
- Stress Responses and Cortisol
- Regulation of Appetite and Obesity
- Zebrafish Biomedical Research Applications
- Pain Mechanisms and Treatments
- Nicotinic Acetylcholine Receptors Study
- Attention Deficit Hyperactivity Disorder
- Forensic Toxicology and Drug Analysis
- Neural dynamics and brain function
- Biochemical Analysis and Sensing Techniques
- Substance Abuse Treatment and Outcomes
- Neuropeptides and Animal Physiology
- Cannabis and Cannabinoid Research
- Adipose Tissue and Metabolism
- Neurological disorders and treatments
- Neural and Behavioral Psychology Studies
- Diet and metabolism studies
- Psychedelics and Drug Studies
- EEG and Brain-Computer Interfaces
- Neuroscience and Neural Engineering
- Hormonal Regulation and Hypertension
The Graduate Center, CUNY
2014-2025
Queens College, CUNY
2016-2025
City University of New York
2012-2023
Queens University of Charlotte
2013-2014
University of Mississippi Medical Center
1998-2002
State Street (United States)
1998-2002
University of Mississippi
2002
Concordia University
1996-2000
May Institute
2000
Carleton University
1995-1996
Moment-to-moment fluctuations of nucleus accumbens dopamine (DA) were determined in rats self-administering or passively receiving “yoked” intravenous infusions d -amphetamine. The initial lever presses each session caused elevations DA concentration, usually to an peak that was not maintained throughout the rest session. As (“loading”) injections metabolized, levels dropped toward baseline but sustained at elevated plateaus by subsequent pressing spaced remainder 3 hr sessions. During this...
This study was designed to assess the involvement of D1 dopamine actions in ventral tegmental area (VTA) on intravenous cocaine self-administration. Rats were trained self-administer injections (1.0 mg/kg per injection) a fixed-ratio 1 (FR-1) schedule or progressive ratio (PR) reinforcement and then tested under influence bilateral VTA receptor antagonist SCH 23390 5-HT2 ketanserin. increased self-administration FR-1 but decreased it PR schedule. Injections ketanserin ineffective, as site mm...
In the present study we tested hypothesis that baclofen, a GABA-B receptor agonist, attenuates methamphetamine self-administration. Fifteen rats were trained to self-administer i.v. injections of (0, 0.0625, 0.125 and 0.25 mg/kg/injection) on progressive ratio schedule reinforcement, then under influence two doses baclofen (2.5 or 5.0 mg/kg, i.p.). Baclofen significantly reduced break points at all methamphetamine, producing dose-orderly shift dose–response function right. These data suggest...
There is a strong link between chronic stress and vulnerability to drug abuse addiction. Corticotropin releasing factor (CRF) central the response that contributes continuation relapse heroin abuse. Chronic exposure can exacerbate CRF production, leading dysregulation of midbrain CRF-dopamine-glutamate interaction.Here we investigated role CRF1 receptors in self-administration assessed neuroplasticity receptor expression key opioid addiction brain regions.Infusions antalarmin (a antagonist)...
The present study investigated the effects of dopamine (DA) D1 selective agonist, SKF 38393, and D2 agonists, quinpirole bromocriptine, on responding for conditioned reward. nonselective DA agonist apomorphine indirect amphetamine, were also evaluated. Male rats (n = 302) tested in a procedure consisting three distinct phases. During pre-exposure phase exposed to an operant chamber containing two levers; one lever produced lights-off stimulus (3s) other tone (3s). This was followed by 4...
The objective of this study was to test the hypothesis that environmental enrichment (EE) administered rats previously trained self-administer cocaine would reduce responding in extinction and a cocaine-context renewal test. Long-Evans male were press an active lever reinforced by (1.0 mg/kg/injection) under fixed-ratio 1 schedule reinforcement (inactive presses produced no consequences). After stable established, all given 10-day break from operant chambers followed random assignment EE...