Alina Carmen Porojnicu

ORCID: 0000-0002-6670-8699
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Vitamin D Research Studies
  • Climate Change and Health Impacts
  • Venous Thromboembolism Diagnosis and Management
  • Skin Protection and Aging
  • Cutaneous Melanoma Detection and Management
  • Air Quality and Health Impacts
  • Vitamin C and Antioxidants Research
  • Cancer Risks and Factors
  • Atrial Fibrillation Management and Outcomes
  • Breast Cancer Treatment Studies
  • Allergic Rhinitis and Sensitization
  • Cancer Treatment and Pharmacology
  • Menstrual Health and Disorders
  • melanin and skin pigmentation
  • Breast Lesions and Carcinomas
  • Folate and B Vitamins Research
  • Nutrition, Genetics, and Disease
  • Bone health and osteoporosis research
  • Thermoregulation and physiological responses
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Psoriasis: Treatment and Pathogenesis
  • Breast Implant and Reconstruction
  • Colorectal Cancer Surgical Treatments
  • Global Cancer Incidence and Screening
  • Chemotherapy-induced cardiotoxicity and mitigation

Drammen Hospital
2015-2025

Vestre Viken Hospital Trust
2020-2025

Akershus University Hospital
2018-2019

Oslo University Hospital
2009-2015

Norwegian Cancer Society
2005-2011

Compello (Norway)
2010

UiT The Arctic University of Norway
2009

Carol Davila University of Medicine and Pharmacy
2005-2007

Solar radiation is the main cause of skin cancers. However, it also a source vitamin D for humans. Because optimal status protects against internal cancers and number other diseases, controversy exists: Will increased sun exposure lead to net health benefits or risks? We calculated relative yield photosynthesis as function latitude with radiative transfer model cylinder geometry human surface. The annual 3.4 4.8 times larger below equator than in U.K. Scandinavia, respectively. In...

10.1073/pnas.0710615105 article EN Proceedings of the National Academy of Sciences 2008-01-08

There are no data on the effect of low-dose anticoagulation as secondary prophylaxis for venous thromboembolism (VTE) in cancer patients. We assessed efficacy and safety apixaban 30 months, after initial 6 months full-dose treatment.We included 298 patients with any type VTE a single arm interventional clinical trial. All were treated (5 mg twice daily) months. Total 196 active treatment continued 2.5 daily another The main endpoints recurrent VTE, major bleeding clinically relevant...

10.1111/jth.15666 article EN cc-by-nc Journal of Thrombosis and Haemostasis 2022-02-03

•Forty-five percent of patients assigned to CT by routine classification were de-escalated no the Prosigna test.•The test identified lower-risk with molecular higher risk who offered escalated systemic treatment.•Incorporating in diagnostic work-up significantly reduced treatment discrepancies between hospitals.•The correlations Ki67 and ROR score among within different treatment/risk groups poor. BackgroundEMIT-1 is a national, observational, single-arm trial designed assess value Prosigna,...

10.1016/j.esmoop.2024.103475 article EN cc-by ESMO Open 2024-06-01

A variety of studies have shown beneficial effects different types phototherapy in skin disorders. Such therapy leads to enhanced cutaneous vitamin D synthesis, which may be one the mechanisms action. Furthermore, another nutrient, folate, can probably also influenced by UV radiation.The aim our study was investigate influence low-dose narrowband UVB (nUVB) patients with psoriasis, atopic eczema and other disorders on serum levels 25(OH) (the marker for status) erythrocyte-folate.25(OH)...

10.1111/j.1600-0625.2009.00987.x article EN Experimental Dermatology 2009-10-22

Experimental studies show that vitamin D derivatives are potent anticarcinogenic factors. Epidemiological observations support this, and sufficiency has been hypothesised to be an important risk-reducing factor in several forms of cancer. Vitamin level exhibits seasonal variations. In the present work, we have investigated effect season diagnosis on risk death among Hodgkin's lymphoma patients diagnosed Norway between 1964 2000. Risk estimates were calculated as relative (RR), with 95%...

10.1038/sj.bjc.6602722 article EN cc-by-nc-sa British Journal of Cancer 2005-08-02

Solar ultraviolet (UV) radiation during the summer and vitamin D supplementation are two major sources of for humans at northern latitudes. However, little is known about relative efficiency these sources.The main goal was to compare high-dose oral D3 (2000 IU per day 30 days) with a simulated UV exposure [10 sunbed sessions total dose 23·8 standard erythema doses (SED)] improve status.Healthy volunteers were randomized into groups: group 1 received followed by 10 whole-body exposures; 2...

10.1111/bjd.12349 article EN British Journal of Dermatology 2013-04-01

Introduction It is unclear how drug-interaction with apixaban influences recurrent venous thromboembolism (VTE) and bleedings in cancer patients. Methods A post-hoc analysis of a single-arm interventional clinical trial on treatment patients VTE to investigate whether the occurrence any endpoints could be associated concurrent use an interacting drug. Drugs taken by during period were categorized as either increasing bleeding risk, thrombosis both or neither. Results 298 divided into groups...

10.3389/fonc.2025.1520725 article EN cc-by Frontiers in Oncology 2025-01-27

10.1016/j.jphotobiol.2008.02.007 article EN Journal of Photochemistry and Photobiology B Biology 2008-03-03

Abstract BACKGROUND We have earlier found that the prognosis for several cancers is dependent on season of diagnosis. More recently, both prostate cancer incidence and mortality been shown to increase with increasing latitude, which probably relates photosynthesis vitamin D. METHODS The 3 year survival patients has analyzed Cox regression method two age groups at different latitudes in Norway. RESULTS Patients diagnosed during summer autumn had best (Ralative risk (RR) death 0.8; 95% CI...

10.1002/pros.20577 article EN The Prostate 2007-07-11

Abstract Low levels of vitamin D and excess body weight are both factors associated with increased risk cancer. The seems to be proportional the increase in BMI, decrease serum 25‐hydroxyvitamin (25(OH)D) level. Our earlier investigations suggest that 25(OH)D increasing BMI. Although connection between cancer risk, BMI status might arbitrary, it has not been discussed literature so far. In this study, we analyze data published current meta‐analysis, prospective studies, systematic reviews on...

10.1002/mnfr.200900512 article EN Molecular Nutrition & Food Research 2010-05-28

Lagunova Z, Porojnicu AC, Lindberg FA, Aksnes L, Moan J. Vitamin D status in Norwegian children and adolescents with excess body weight. Objectives: The prevalence of childhood adolescent obesity has increased during the past decades. A high mass index (BMI) is associated a low vitamin status. purpose this study was to determine deficiency insufficiency Methods: seasonal variations 25(OH)D 1,25(OH)2D were analyzed 102 (70 girls 32 boys), 8–19 yr age, overweight obesity. Results: Overall, 50%...

10.1111/j.1399-5448.2010.00672.x article EN Pediatric Diabetes 2010-09-07

The objectives of this work were: (1) To determine whether repeated exposures to small doses from a commercial sun bed (Wolff Solarium Super Plus 100 W) over 5 weeks gave less vitamin D than twice as large, but still nonerythemogenic, doses. (2) investigate the contribution status such sessions was dependent on baseline before start sessions. (3) decay rate induced increment D. raised 25-hydroxyvitamin levels typical winter values summer values. mean value after exposure being 80 nm (+/-14)...

10.1111/j.1751-1097.2009.00607.x article EN Photochemistry and Photobiology 2009-09-24
Coming Soon ...