A5020509161- Neuroscience and Neural Engineering
- Conducting polymers and applications
- Neural dynamics and brain function
- Electrochemical sensors and biosensors
- Advanced Memory and Neural Computing
- Photoreceptor and optogenetics research
- Electrochemical Analysis and Applications
- Nanowire Synthesis and Applications
- Silicon Nanostructures and Photoluminescence
- Photonic and Optical Devices
- Cell Adhesion Molecules Research
- Liquid Crystal Research Advancements
- Antimicrobial Peptides and Activities
- Solidification and crystal growth phenomena
- Thin-Film Transistor Technologies
- Osteoarthritis Treatment and Mechanisms
- Analytical Chemistry and Sensors
- Graphene research and applications
- Advanced Sensor and Energy Harvesting Materials
- Fluid Dynamics and Thin Films
- Neuroscience and Neuropharmacology Research
Massachusetts Institute of Technology
2020-2021
University of Algarve
2016-2020
Instituto de Telecomunicações
2016-2020
Universitat Rovira i Virgili
2010
Extracellular electrode recording demonstrates acid-triggered electrical activity in glioma cell populations.
An electrical method to measure extracellular bioelectrical activity in vitro is presented. This exploits the Helmholtz capacitive double-layer established at electrode surface. Small voltage variations order of μVs induce through capacitor a displacement current that measured. then enhanced by gain factor proportional capacitance. In addition, when measurements are carried out low frequencies mode contribution noise can be minimized. The performance electrodes and demonstrated using...
Conducting polymer electrodes based on poly (3, 4 ethylenedioxythiophene):polystyrene sulfonate were used to record electrophysiological signals from autonomous cardiac contractile cells present in embryoid bodies. Signal detection was carried out by measuring the displacement current across polymer/electrolyte double-layer capacitance, and compared with voltage detection. While for relatively low capacitance electrodes, amplification provides higher signal quality, high capacitive method...
Abstract Ultra-sensitive electrodes for extracellular recordings were fabricated and electrically characterized. A signal detection limit defined by a noise level of 0.3–0.4 μV bandwidth 12.5 Hz was achieved. To obtain this high sensitivity, large area (4 mm 2 ) used. The electrode surface is also micro-structured with an array gold mushroom-like shapes to further enhance the active area. In comparison flat surface, increases capacitance electrode/electrolyte interface 54%. low impedance...
Astrocytes are neural cells that exhibit functional electrical properties sensitive to neuronal activity and capable of modulating neurotransmission. Thus, electrophysiological recordings astroglial very attractive study the dynamics glial signaling. This contribution reports on use ultra-sensitive planar electrodes combined with low noise frequency amplifiers enable detection extracellular signals produced by primary cultures astrocytes isolated from rat cerebral cortex. Recorded is...
Silicon photonics realized in CMOS processes has transformed computing, communications, sensing, and imaging. Although silicon is an indirect bandgap material prohibiting efficient light generation, considerable work been conducted the field of p-n junctions emitting broadband visible when operating high-voltage reverse breakdown avalanching mode. Here, we demonstrate high-brightness near-infrared (NIR) emission for forward-biased micro-light diodes (micro-LEDs) open-foundry microelectronic...
Conducting polymer electrodes based on poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) are used to record extracellular signals from autonomous cardiac contractile cells and glioma cell cultures. The performance of these conducting is compared with Au electrodes. A small-signal impedance analysis shows that in the presence an electrolyte, both establish high capacitive double-layers. However, polymer/electrolyte interfacial resistance 3 orders magnitude lower than...
Silicon photonics realized in CMOS processes has transformed computing, communications, sensing and imaging. Although silicon is known as an indirect bandgap material, substantial progress been made the field of p-n junctions emitting visible light when operating reverse breakdown avalanching mode. Here, we demonstrate high-brightness infrared emission forward bias for a vertical junction open-foundry process – 55 BCDLite. Emission intensity over 40 mW/cm <sup...
A 3D numerical simulation is presented here to analyze the growth of doped KGd(PO3)4 single crystals. quasi-steady approximation whole based on three independent sets simulations considering different crystal sizes has been made. Under this approximation, steady axial flow rate shows a double linear dependence size and rotation externally applied. In addition, present calculations indicate that sixteen vanes rotating platinum stirrer used in real experiments does not improve toward...
Abstract This work provides an experimental characterization and equivalent circuit modelling of electrochemically gated field effect transistors (EGFETs) using a graphene layer. The aim is to demonstrate the detection limit these sensing devices for bioelectronics applications. Towards that, we present detail study the; (i) sources intrinsic noise, (ii) ionic density in charge transfer resistance (iii) existence parasitic conducting paths surrounding electrolyte. To investigate liquid-based...