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Contact & Profiles
Research Areas
- Advanced Fluorescence Microscopy Techniques
- Neonatal Respiratory Health Research
- Photoreceptor and optogenetics research
- Advanced Electron Microscopy Techniques and Applications
- Fetal and Pediatric Neurological Disorders
- Cerebrospinal fluid and hydrocephalus
McGovern Institute for Brain Research
2024
Abstract The glymphatic movement of fluid through the brain removes metabolic waste 1–4 . Noninvasive 40 Hz stimulation promotes neural activity in multiple regions and attenuates pathology mouse models Alzheimer’s disease 5–8 Here we show that multisensory gamma influx cerebrospinal efflux interstitial cortex 5XFAD model disease. Influx was associated with increased aquaporin-4 polarization along astrocytic endfeet dilated meningeal lymphatic vessels. Inhibiting clearance abolished removal...
10.1038/s41586-024-07132-6
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cc-by
Nature
2024-02-28
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