A5102731603- Reproductive tract infections research
- Spaceflight effects on biology
- Bone health and osteoporosis research
- Syphilis Diagnosis and Treatment
- Isotope Analysis in Ecology
- Urinary Tract Infections Management
- Genital Health and Disease
- Pelvic floor disorders treatments
- Body Composition Measurement Techniques
- Nutrition and Health in Aging
- Effects of Radiation Exposure
- Adolescent Sexual and Reproductive Health
- Mitochondrial Function and Pathology
- HIV/AIDS Research and Interventions
- Urological Disorders and Treatments
- Urinary and Genital Oncology Studies
- Metabolism and Genetic Disorders
- Iron Metabolism and Disorders
- Space Exploration and Technology
- Climate Change and Health Impacts
- Air Quality and Health Impacts
- Muscle metabolism and nutrition
- Diet and metabolism studies
- Reproductive Health and Technologies
- Sex work and related issues
Public Health – Seattle & King County
2017-2024
Deloitte (United States)
2023
Procter & Gamble (United States)
2020-2022
Seattle University
2017-2021
University of Washington
2018
Johnson Space Center
2012-2016
Oak Ridge Associated Universities
2012-2016
Azusa Pacific University
2014
Universities Space Research Association
2013
Oak Ridge National Laboratory
2013
Following identification of a case coronavirus disease 2019 (COVID-19) in health care worker, 76 82 residents long-term skilled nursing facility were tested for SARS-CoV-2; 23 (30.3%) had positive test results, approximately half whom asymptomatic or presymptomatic on the day testing.
Challenging conventional wisdom, Morgan reveals how expectations regarding gender and reproduction were central to racial ideologies, the organization of slave labour, nature community resistance. She compares experiences slavery endured by different sexes.
On February 28, 2020, a case of coronavirus disease (COVID-19) was identified in woman resident long-term care skilled nursing facility (facility A) King County, Washington.* Epidemiologic investigation A 129 cases COVID-19 associated with A, including 81 the residents, 34 staff members, and 14 visitors; 23 persons died. Limitations effective infection control prevention members working multiple facilities contributed to intra- interfacility spread. can spread rapidly residential facilities,...
The ability to rapidly detect changes in bone mineral balance (BMB) would be of great value the early diagnosis and evaluation therapies for metabolic diseases such as osteoporosis some cancers. However, measurements BMB are hampered by difficulties with using biochemical markers quantify relative rates resorption formation need wait months years altered produce density large enough resolve X-ray densitometry. We show here that, humans, natural abundances Ca isotopes urine change response...
Bone loss, a key concern for long-duration space travelers, is typically considered female issue. The number of women who have flown missions now great enough to allow quantitative comparison changes in bone and renal stone risk by sex. Participants were 42 astronauts (33 men 9 women) on the International Space Station. mineral density (by dual-energy X-ray absorptiometry) biochemical markers metabolism (from blood urine samples) evaluated before after flight. Data analyzed two groups, based...
Abstract Background Nongonococcal urethritis (NGU) is a common syndrome with no known etiology in ≤50% of cases. We estimated associations between urethral bacteria and NGU men who have sex (MSM) women (MSW). Methods Urine was collected from cases (129 MSM, 121 MSW) controls (70 114 attending Seattle STD clinic. Cases had ≥5 polymorphonuclear leukocytes on Gram stain plus symptoms or discharge; <5 PMNs, symptoms, discharge. considered idiopathic when Neisseria gonorrhoeae, Chlamydia...
Despite the importance of Fe−organic complexes in environment, few studies have investigated Fe isotope effects driven by changes coordination that involve organic ligands. Previous experimental (Dideriksen et al., 2008, Earth Planet Sci. Lett. 269:280−290) and theoretical (Domagal-Goldman 2009, Geochim. Cosmochim. Acta 73:1−12) disagreed on sense fractionation between Fe−desferrioxamine B (Fe−DFOB) Fe(H2O)63+. Using a new technique employs dialysis membrane to separate equilibrated...
Bed rest studies provide an important tool for modeling physiological changes that occur during spaceflight. Markers of bone metabolism and nutritional status were evaluated in 12 subjects (8 men, 4 women; ages 25–49 yr) who participated a 30-day −6° head-down-tilt diet-controlled bed study. Blood urine samples collected twice before, once week during, after rest. Data analyzed using mixed-effects linear regression with priori contrasts comparing all days to the second pre-bed acclimation...
We describe a new chemical separation method to isolate Ca from other matrix elements in biological samples, developed with the long-term goal of making high-precision measurement natural stable isotope variations clinically applicable tool assess bone mineral balance. A two-column procedure utilizing HBr achieves purity required accurately and precisely measure two ratios ((44)Ca/(42)Ca (44)Ca/(43)Ca) on Neptune multiple collector inductively coupled plasma mass spectrometer (MC-ICPMS)...
During early spaceflights, many crewmembers did not meet their caloric requirements and consequently lost body mass during flight, as assessed by a decrease in postflight mass. Maintaining spaceflight is crucial for maintaining crew health monitoring thus important to medical operations well being key component of human research. Determining becomes difficult microgravity environment.We report data from two measurement devices on the International Space Station (ISS): Russian measuring...
Transgender inclusive and gender affirmative healthcare includes asking patients about identity sex assigned at birth through what is known as the "2-step" methodology. In May 2016, sexually transmitted disease (STD) clinic in Seattle, WA switched from using a 1-step to 2-step question. We aimed determine if updated questions increased ascertainment of transgender nonconforming (TGNC) used improved data describe human immunodeficiency virus/STD risk profile TGNC patients.We conducted...
Although Mycoplasma genitalium (MG) is an acknowledged cause of nongonococcal urethritis (NGU), access to diagnostic testing limited. Syndromic management common, yet little known about natural history.
Abstract Epidemiologic studies have shown the health risks of exposure to cigarette smoke and air pollution, with heavy metal composition implicated as contributing both. Environmental has been epidemiologically associated pancreatic cancer, but pathophysiologic basis for this is not yet clear. In current work, we used inductively coupled plasma mass spectrometry quantify juice collected in response secretin stimulation successive patients evaluated abdominal pain (35 30 chronic...
Radiation exposure in combination with other space environmental factors including microgravity, nutritional status, and deconditioning is a concern for long-duration exploration missions. Astronauts experience altered iron homeostasis due to adaptations microgravity an iron-rich food system. Iron intake reaches three six times the recommended daily allowance use of fortified foods on International Space Station. associated certain optic neuropathies can potentiate oxidative stress. This...
The purpose of this study was to directly assess sex differences in bone loss, biochemistry, and renal stone risk bed rest. Bed rest simulates some spaceflight effects on human physiology can be used address the potential existence sex-specific metabolism space. We combined data from control subjects five head-down-tilt studies (combined n = 50 men, 24 women) differing durations (14–90 days). All were healthy volunteers. Mean age 35 ± 9 years for women 33 8 men. main outcome measures density...
Astronauts are exposed to increased body iron stores and radiation, both of which can cause oxidative damage leading negative health effects. The purpose this study was investigate combined effects high dietary (650 mg/kg diet) radiation exposure (0.375 Gy cesium-137 every other day for 16 d) on markers stress, immune system function, colon mucosal environment in male Sprague-Dawley rats (n=8/group). Control consumed adequate (45 were not irradiated. Combined treatments liver glutathione...
Centers for Disease Control and Prevention (CDC) guidelines recommend 240 mg gentamicin plus 2 g azithromycin the treatment of gonorrhea in cephalosporin-allergic patients. The efficacy alone pharyngeal is uncertain.Between September 2018 March 2019, we enrolled men who have sex with nucleic acid amplification test-diagnosed a single-arm, unblinded clinical trial. Men received single 360-mg intramuscular dose underwent test cure by culture 4-7 days later. study measured creatinine at...
Abstract This essay introduces the special issue with a critique of Cedric Robinson’s heuristic, “racial capitalism,” and discussion our titular intervention: “reproductive racial capitalism.” The is necessarily grounded in reproductive crisis present day. It centers histories afterlives hereditary slavery radical contestations refusals its logics. Overall, it argues that contemporary capitalism always already reproductive. Reproductive labor experiences conception, gestation, parturition,...
Abstract From February 2015 to October 2017, among 20 men who have sex with Mycoplasma genitalium -associated nongonococcal urethritis, 15% had macrolide resistance and S83I ParC mutations. Azithromycin followed by moxifloxacin cleared in 2 of 11 13 without Dual failures were after doxycycline. mutations not associated failure.
Airborne particulate matter (PM) pollution is an environmental and health concern. The impact of PM has typically focused on the respiratory system. skin been largely understudied due to lack a quantitative method measure deposition skin. This manuscript presents quantify using elemental markers as proxy for PM. Skin tape strips were collected from forehead buttock 100 outdoor workers in Beijing, China. samples analyzed 19 inductively coupled plasma mass spectrometry. To determine specific...
Objective Although Chlamydia trachomatis (CT) and Mycoplasma genitalium (MG) are major causes of non-gonococcal urethritis (NGU), up to 50% cases unknown aetiology. We sought identify urethral exposures at last sexual episode associated with NGU non-CT/non-MG anatomical sites from which aetiologically relevant micro-organisms may be acquired. Methods enrolled STD clinic patients without assigned male sex birth age ≥16 into a cross-sectional study. was symptoms or visible discharge plus ≥5...