A5033707369- Muscle metabolism and nutrition
- Birth, Development, and Health
- Adipose Tissue and Metabolism
- Muscle Physiology and Disorders
- Diet and metabolism studies
- Exercise and Physiological Responses
- Gestational Diabetes Research and Management
- Mitochondrial Function and Pathology
- Regulation of Appetite and Obesity
- Adipokines, Inflammation, and Metabolic Diseases
- Obesity, Physical Activity, Diet
- Metabolism and Genetic Disorders
- Genetic and phenotypic traits in livestock
- Information Science and Libraries
- Global Health Care Issues
- Migration, Aging, and Tourism Studies
- Cerebral Palsy and Movement Disorders
- Metabolism, Diabetes, and Cancer
- Cancer, Hypoxia, and Metabolism
- Offshore Engineering and Technologies
- Neonatal and fetal brain pathology
- Youth, Drugs, and Violence
- Pregnancy and preeclampsia studies
- Nutritional Studies and Diet
- Structural Integrity and Reliability Analysis
Universidade Federal de Pernambuco
2012-2024
Universidade de São Paulo
2011-2022
Universidade Federal do Espírito Santo
2022
Instituto Politécnico de Lisboa
2019
University of Lisbon
2019
Vale (Brazil)
2011
In this study, we investigated the effect of glutamine (Gln) supplementation on signaling pathways regulating protein synthesis and degradation in skeletal muscle rats with streptozotocin (STZ)-induced diabetes. The expression levels key regulatory proteins synthetic (Akt, mTOR, GSK3 4E-BP1) (MuRF-1 MAFbx) were determined using real-time PCR Western blotting four groups male Wistar rats; 1) control, non-supplemented glutamine; 2) supplemented 3) diabetic, 4) glutamine. Diabetes was induced...
INTRODUÇÃO: Excesso de alimentação no início da vida pode modificar persistentemente consumo e peso corporal. Adoção exercício físico é uma estratégia útil para evitar excessivo ganho peso. OBJETIVO: Avaliar o crescimento corporal a eficiência alimentar em ratos provenientes ninhada reduzida aleitamento. MÉTODOS: Ao terceiro dia vida, ninhadas foram formadas com quatro (GN4) ou 10 animais (GN10), (n = 25). desmame, machos Wistar permaneceram gaiolas individuais, e, aos 60 (± 2) dias...
The aim of this study was to evaluate the effect overload-induced hypertrophy on extensor digitorum longus (EDL) and soleus muscles streptozotocin-induced diabetic rats. absolute tetanic twitch forces increases in EDL were not different between control Phospho-Akt rpS6 contents increased muscle after 7 days overload returned pre-overload values 30 days. In muscle, total phospho-Akt both groups Akt controls rats remained mRNA expression animals showed an increase MGF follistatin a decrease...
Abstract Cerebral palsy (CP) is characterized by brain damage at a critical period of development the central nervous system, and, as result, motor, behavioural and learning deficits are observed in those affected. Flavonoids such kaempferol have demonstrated potential anti‐inflammatory neuroprotective properties for neurological disorders. This study aimed to assess effects neonatal treatment with on body development, grip strength, gait performance morphological biochemical phenotype...
What is the central question of this study? Oleic and linoleic acids modulate fibroblast proliferation myogenic differentiation in vitro. However, their vivo effects on muscle regeneration have not yet been examined. We investigated either oleic or acid a well-established model after severe laceration. main finding its importance? found that increases fibrous tissue deposition impairs recovery contractile function, whereas has opposite severely injured gastrocnemius muscle, suggesting...
The effect of a short-term creatine supplementation on hindlimb suspension (HS)-induced muscle atrophy was investigated. Creatine monohydrate (5 g/kg b.w. per day) or placebo, divided in 2 daily doses, given by oral gavage for 5 days. Rats were maintained HS with dietary concomitantly Body weight, soleus and EDL masses, cross-sectional areas (CSA) the fibers measured. Signaling pathways associated skeletal mass regulation (FST, MSTN, FAK, IGF-1, MGF, Akt, mTOR, atrogin-1, MuRF1 expressions,...
The effects of pregestational and gestational low-to-moderate physical training on insulin secretion in undernourished mothers were evaluated. Virgin female Wistar rats divided into four groups as follows: control (C,<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mrow><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn>5</mml:mn></mml:mrow></mml:math>); trained (T,<mml:math id="M2"><mml:mrow><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn>5</mml:mn></mml:mrow></mml:math>);...
The nutritional transition that the western population has undergone is increasingly associated with chronic metabolic diseases. In this work, we evaluated a diet rich in saturated fatty acids (hyperlipidic, HL) after weaning of offspring rats submitted to maternal protein restriction on hepatic mitochondrial bioenergetics. Wistar were mated and during gestation lactation, mothers received control diets (NP, normal content 17%) or low (LP, 8% protein). After weaning, either NL (normolipidic)...
Skeletal mass loss is reported in several catabolic conditions and it has been associated with a reduced intracellular L-glutamine content. We investigated the association of concentration protein content skeletal muscle cells.We cultivated C2C12 myotubes absence or presence 2 (reference condition), 8 16 mM for 48 hours, variations contents amino acids proteins measured. used an inhibitor synthesis (L-methionine sulfoximine - MSO) to promote further reduction levels. Amino cells media were...
Obesogenic diets are known to induce obesity and changes in food intake experimental animals. Obesity negatively affects the peripheral metabolism neural aspects, such as eating behavior. In obese animals, dopamine (DA) receptor levels reduced. DA is one of main peptides involved motivation pleasure eating. A combination naltrexone/bupropion (NB) has shown promise controlling metabolic alterations, but there few studies on how they modulate dopaminergic expression. NB, addition reducing body...
A incompatibilidade entre a desnutrição perinatal e uma nutrição adequada durante o desenvolvimento aumenta risco de aparecimento precoce doenças não transmissíveis na vida adulta. Todavia, acredita-se que atividade física materna possa atenuar estas consequências. O presente estudo teve como objetivo avaliar os efeitos do treinamento físico gestação evolução ponderal, circunferência abdominal, glicemia colesterolemia filhotes adultos submetidos à perinatal. Ratas Wistar (n = 12) foram...
Perinatal exposure to a poor nutritional environment predisposes the progeny development of metabolic disease at adult age, both in experimental models and humans. Numerous adaptive responses maternal protein restriction have been reported tissues. However, expression glucose/fatty acid metabolism-related genes adipose tissue liver needs be described.To evaluate impact perinatal malnutrition, we determined malnutrition-associated gene alterations tissue.In present study, evaluated...
Jacinto Rodrigues nasceu em Luanda, no dia 28 de Outubro 1939. E Professor Catedratico na Universidade do Porto (Portugal), com licenciatura Filosofia, mestrado Urbanismo e doutoramento Historia Arte. investigador Centro Estudos Africanos da Porto. Autor dezenas livros artigos cariz cientifico, podendo citar-se como exemplos os Sociedade Territorio. Desenvolvimento Ecologicamente Sustentado (Porto, 2006), A Conspiracao Solar Padre ...
Introduction: The promotion of physical activity in school is characterized by improvements the quality life forstudents. In this context, education teacher's has a fundamental role school, and it essential to act thesecases. Training during graduation course on how emergency situations lead differentsituations. Methodology: Bibliographic review subject. Original articles were used between 2010-2018 obtainedfrom researches conducted electronic databases free-access scientific sites:...
Wind power technologies are being used as a mean of harvesting the energy from wind with low carbon impact and great potential to contribute new paradigm. Great benefits may arise use offshore turbines, such having reduced visual impact, if far enough coast, or able produce more due bigger turbines. Current challenges for these include producing stable profitable platform that allow turbines be installed in deep waters, meaning solutions need floating type. An example structure is foundation...