Mass customization aims to provide goods and services that meet each individual customer's needs with a level of efficiency close mass production. It is also viable smart manufacturing strategy for companies want gain competitive advantage in the current business environment. Product configurators are one major toolkits enabling customization. Existing product require customers choose from set predefined attributes or list component alternatives. However, may feel confused when configuring...

This study aims to investigate the epidemiological characteristics of various bacteria carrying ARGs on a global scale over extended time periods. A total 25,285 globally isolated bacteria's genomes were analyzed explore ARGs. The analysis focused temporal, geographic, and species distribution, including pathogenic non-pathogenic bacteria, intracellular parasitic states, ARG types, their association with MGEs. Multiple linear regression was employed identify risk factors in bacteria. overall...

Abstract NLRP3 inflammasome is activated by diverse stimuli including infections, intracellular and environmental irritants. How senses these unrelated what activates remain unknown. Here we report that signal-dependent phase separation initiated its activation, in which the palmitoyltransferase ZDHHC7-mediated tonic palmitoylation an IDR region FISNA domain of play important roles. Moreover, three conserved hydrophobic residues critically mediate multivalent weak interactions....

This work presents a monolithically integrated temperature and humidity sensor based on microelectromechanical systems technology. The working the “bi-metallic” effect has advantages of wide range, high sensitivity, fast detection. polyimide parallel plate capacitive structure with microporous array upper electrode designed for sensitivity response. Numerical analysis COMSOL simulation showed that detection is 0.2 mV/°C in range 193–393 K 0.405 pF/% relative (RH) response time 34 s 0%–100%...

A China Fusion Engineering Testing Reactor (CFETR) will be built to test and verify the feasibility of engineering technology in practice for future fusion reactor. Long pulse steady-state operation demonstrated with duty cycle time more than 30%–50%. Because beta gamma activation component bulk surface dust (beryllium, carbon, tungsten), special remote handling (RH) techniques required during machine maintenance periods. The divertor cassettes' replacement is one key operations CFETR meet...

The application of graph representation learning techniques to the area financial risk management (FRM) has attracted significant attention recently. However, directly modeling transaction networks using neural models remains challenging: Firstly, are directed multigraphs by nature, which could not be properly handled with most current off-the-shelf (GNN). Secondly, a crucial problem in FRM scenarios like anti-money laundering (AML) is identify risky transactions and naturally cast into an...

The ultraviolet imaging detection is one of the important methods power equipment insulation, which great significance for insulation state, ensuring its normal and safe operation, reduction system safety accidents. According to characteristics image, threshold method, noise algorithm based on mathematical morphology area filtering, four neighborhood connection method are used extract discharge in image calculate area. this paper deal with partial insulator string, extracted agrees well...

The study aimed to investigate the prevalence of antibiotic resistance genes (ARGs) within ecosystem natural plague foci, assessing their potential impact on efficacy treatments. Employing 16S rRNA gene sequencing and high-throughput quantitative PCR, microbial communities ARGs were detected, with subsequent analysis interactions among ARGs, mobile genetic elements (MGEs), environmental factors, species. Tetracycline found be dominant, multidrug tetracycline primarily associated marmots...

Fast inspection and light maintenance capability is already a clear demand to control the tokamak condition improve efficiency of experimental campaigns. EAST remote system has been developed implement grasping tasks during plasma. The paper presents design description EAMA (EAST articulated arm) robot, gripper CASK. field commissioning was performed both in mockup demonstrate availability functionalities system. To be able realize fully routine operation on EAST, improvement proposed with...

The auxiliary material is often used to reduce the resistance of transmission line tower grounding grid for limitation extension and vertical reduction measures. For lack unified standard guidance when modules are in actual project, some problems occurred application such as blind construction low efficiency. In this paper, common lightning protection software CDEGS simulate calculate influencing factors module grid. First all, simulation carried out laying position density "one" shaped...

Recent gradual improvement of the distributed electric resources (DER) penetration results in change original topology and power flow direction network. The short circuit current, which is provided by resources, has changed network fault current both size distribution, will reduce protection sensitivity, bring negative impacts such as blinding tripping. However, actual structures active distribution are complex, it difficult to measure impact levels traditional methods. These situations must...

In this paper we discuss the new challenge for using simulation modeling tools to support decision making in a multiple-user environment when organizations make business process changes complex logistics systems. Current based are mainly single-level oriented and lack capability efficiency analysis used by multiple users. Operational freedom configuring executable models is required users conduct customized services. This motivated design an architecture configurable hierarchical flexible...

The application of graph representation learning techniques to the area financial risk management (FRM) has attracted significant attention recently. However, directly modeling transaction networks using neural models remains challenging: Firstly, are directed multigraphs by nature, which could not be properly handled with most current off-the-shelf (GNN). Secondly, a crucial problem in FRM scenarios like anti-money laundering (AML) is identify risky transactions and naturally cast into an...

In recent years, with the rapid development of economy and urbanization, a large number parks have been built all over world. The fire accidents occurring in is also increasing, resulting tremendous casualties property damage. These usually cover multiple sub-scenes, such as houses, vehicles greenery, each sub-scene has its own unique accident features. Existing detection methods cannot meet diversity subscenes park. To improve capability model, we propose cloud edge collaboration framework...

In this paper we discuss the new challenge for using simulation modeling tools to support decision making in a multiple-user environment when organizations make business process changes complex logistics systems. Current based are mainly single-level oriented and lack capability efficiency analysis used by multiple users. Operational freedom configuring executable models is required users conduct customized services. This motivated design an architecture configurable hierarchical flexible...