A5023148429- Heart Failure Treatment and Management
- Tissue Engineering and Regenerative Medicine
- Viral Infections and Immunology Research
- Iron Metabolism and Disorders
- Cardiovascular Function and Risk Factors
- Cardiac Fibrosis and Remodeling
- Autoimmune and Inflammatory Disorders Research
- Organ Donation and Transplantation
- Erythropoietin and Anemia Treatment
- Cardiac tumors and thrombi
- Congenital Anomalies and Fetal Surgery
- Case Reports on Hematomas
- Hemoglobinopathies and Related Disorders
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Organ Transplantation Techniques and Outcomes
- Advanced Battery Technologies Research
- GDF15 and Related Biomarkers
- Galectins and Cancer Biology
- Muscle and Compartmental Disorders
- Connective tissue disorders research
- Pituitary Gland Disorders and Treatments
- Protein Tyrosine Phosphatases
- Pediatric Urology and Nephrology Studies
- Pericarditis and Cardiac Tamponade
- Hematological disorders and diagnostics
Hôpital Rangueil
2011-2018
Inserm
2014-2017
Clinique des Cèdres
2017
Université Toulouse III - Paul Sabatier
2014-2017
Centre Hospitalier Universitaire de Toulouse
2016-2017
Université de Toulouse
2017
Institut de Mathématiques de Toulouse
2015-2016
Institut des Maladies Métaboliques et Cardiovasculaires
2014-2016
Background— The mechanisms by which the heart adapts to chronic pressure overload, producing compensated hypertrophy and eventually failure (HF), are still not well defined. We aimed investigate involvement of T cells in progression HF using a transverse aortic constriction (TAC) model. Methods Results— Chronic was associated with accumulation lymphocytes activated/effector CD4 + within cardiac tissue. After TAC, enlarged mediastinal draining lymph nodes showed high density both CD8 T-cell...
Significance LEOPARD syndrome (multiple L entigines, E lectrocardiographic conduction abnormalities, O cular hypertelorism, P ulmonary stenosis, A bnormal genitalia, R etardation of growth, sensorineural D eafness; LS) is a rare genetic disease associating various developmental defects mainly caused by inactivating mutations the tyrosine phosphatase SHP2 (Src-homology 2 domain-containing 2). key regulator essential signaling pathways (MAPK, PI3K), which confer on major roles in development...
Abstract Aims Tenascin-C (TNC) is an endogenous danger signal molecule strongly associated with inflammatory diseases and poor outcome in patients cardiomyopathies. Its function within pathological cardiac tissue during pressure overload remains poorly understood. Methods results We showed that TNC accumulates after 1 week of transverse aortic constriction (TAC) the heart 12-week-old male mice. By cross bone marrow transplantation experiments, we determined deposition relied on cells not...
Objective Obesity in patients with heart failure (HF) is a factor of better prognosis, supposedly partly because the particular epidemiology HF this population. This study expected to compare parameters severity and mortality without obesity, understand origin paradox. Methods Two hundred twenty‐two nonischemic systolic dysfunction were divided into two groups according their body mass index (≥30 vs. <30 kg/m 2 , respectively) explored for functional prognosis. Results B‐type natriuretic...
•Coronary artery perforation was related to angiosarcoma with prior radiation therapy.•Pericardial effusion must make a neoplastic origin suspicious, even from coronary arteries.•Angiosarcomas are rare complications of radiotherapy that be considered in case complex situations.