A5049068376- Animal Behavior and Reproduction
- Avian ecology and behavior
- Hepatocellular Carcinoma Treatment and Prognosis
- Bat Biology and Ecology Studies
- Plant and animal studies
- Wildlife Ecology and Conservation
- Bird parasitology and diseases
- Physiological and biochemical adaptations
- Telomeres, Telomerase, and Senescence
- Liver Disease Diagnosis and Treatment
- Animal Ecology and Behavior Studies
- Liver Disease and Transplantation
- Abdominal vascular conditions and treatments
- Pancreatic and Hepatic Oncology Research
- MRI in cancer diagnosis
- Genetics, Aging, and Longevity in Model Organisms
- Renal cell carcinoma treatment
- Advanced Glycation End Products research
- Bone Tumor Diagnosis and Treatments
- Soft tissue tumor case studies
- Colorectal Cancer Treatments and Studies
- Adipose Tissue and Metabolism
- Abdominal Trauma and Injuries
- Neuroendocrine regulation and behavior
- melanin and skin pigmentation
Swiss Ornithological Institute
2022-2025
University of Lausanne
2014-2025
University of Aberdeen
2015-2024
University Hospital of Lausanne
2010-2023
Metropolitan University
2020
Clinique de Genolier
2017-2020
University of Geneva
2018
Ecologie & Evolution
2016-2017
Hôpital Orthopédique de la Suisse Romande
2008-2016
Laboratoire de Biométrie et Biologie Evolutive
2012
Abstract Comparative analyses of survival senescence by using life tables have identified generalizations including the observation that mammals senesce faster than similar‐sized birds. These been challenged because limitations life‐table approaches and growing appreciation is more an increasing probability death. Without tables, we examine rates in annual individual fitness 20 individual‐based data sets terrestrial vertebrates with contrasting histories body size. We find widespread wild...
Despite accumulating evidence from in vitro studies that cellular senescence is linked to telomere dynamics, how this relates whole-organism and longevity poorly understood controversial. Using data on length red blood cells long-term survival wild Alpine swifts of a range ages, we report the rate loss are predictive life expectancy, slow erosion relatively long telomeres associated with highest probabilities. Importantly, because rather than chronological age, predict our study provides...
We present the application of a real‐time quantitative PCR assay, previously developed to measure relative telomere length in humans and mice, two bird species, zebra finch Taeniopygia guttata Alpine swift Apus melba . This technique is based on amplification telomeric (TTAGGG) n sequences using specific oligonucleotide primers. Relative expressed as ratio (T/S) repeat copy number (T) control single gene (S). method particularly useful for comparisons individuals within or where same are...
Major life history traits, such as fecundity and survival, have been consistently demonstrated to covary positively in nature, some individuals having more resources than others allocate all aspects of their history. Yet, little is known about which (or state variables) may account for covariation. Reactive oxygen species (ROS) are natural by‐products metabolism and, when ROS production exceeds antioxidant defenses, organisms exposed oxidative stress that can deleterious effects on survival....
One central concept in evolutionary ecology is that current and residual reproductive values are negatively linked by the so-called cost of reproduction. Previous studies examining nature this suggested a possible involvement oxidative stress resulting from imbalance between pro- anti-oxidant processes. Still, data remain conflictory probably because, although damage increases during reproduction, high systemic levels might also constrain parental investment Here, we investigated variation...
Significance Many ecological and evolutionary processes strongly depend on the way natural selection varies over time. However, a gap remains when trying to connect theoretical predictions empirical work this question: Most theory assumes that adaptation involves tracking moving optimum phenotype through time, but is seldom estimated empirically. Here, we have assembled large database of wild bird mammal populations, estimate patterns fluctuations in breeding date its influence variability...
In contrast to mammalian erythrocytes, which have lost their nucleus and mitochondria during maturation, the erythrocytes of almost all other vertebrate species are nucleated throughout lifespan. Little research has been done however test for presence functionality in these cells, especially birds. Here, we investigated those two points one common avian model: zebra finch (Taeniopygia guttata). Transmission electron microscopy showed this small passerine bird, after removal haemoglobin...
<sup>90</sup>Y-microsphere selective internal radiation therapy (SIRT) is a valuable treatment in unresectable hepatocellular carcinoma (HCC). Partition-model predictive dosimetry relies on differential tumor-to-nontumor perfusion evaluated pretreatment <sup>99m</sup>Tc-macroaggregated albumin (MAA) SPECT/CT. The aim of this study was to evaluate agreement between the <sup>99m</sup>Tc-MAA SPECT/CT and posttreatment based <sup>90</sup>Y time-of-flight (TOF) PET/CT. <b>Methods:</b> We compared...
Summary Melanin pigments provide the most widespread source of coloration in vertebrates, but adaptive function such traits remains poorly known. In a wild population tawny owls ( Strix aluco ), we investigated relationships between plumage coloration, which varies continuously from dark to pale reddish, and strength cost an induced immune response. The degree reddishness owl feather colour was positively correlated with concentration phaeomelanin eumelanin pigments, highly heritable (h 2 =...
Summary The relationship between metabolism and reactive oxygen species (ROS) production by the mitochondria has been often (wrongly) viewed as straightforward, with increased leading to higher pro-oxidants generation. Insights on mitochondrial functioning show that consumption is either principally coupled energy conversion ATP or heat, depending whether ATP-synthase uncoupling protein 1 (UCP1) driving respiration. However, those two processes might greatly differ in terms of oxidative...
Costs of reproduction can be divided in mandatory costs coming from physiological, metabolic and anatomical changes required to sustain itself, investment-dependent that are likely become apparent when reproductive efforts exceeding what organisms were prepared sustain. Interestingly, recent data showed entering enhanced breeders' telomere loss, but no explored so far the impact investment. Telomeres protect ends eukaryote chromosomes. Shortened telomeres associated with shorter lifespan,...
Video-assisted thoracic surgery (VATS) is currently performed to diagnose and treat solitary pulmonary nodules (SPN). However, the intra-operative identification of deep can be challenging with VATS as lung difficult palpate. The aim study was report utility results pre-operative computed tomography (CT)-guided hook wire localization SPN.All records patients undergoing CT-guided prior resection for SPN between 2002 2013 were reviewed. efficacy in localizing nodule, complications, necessity...
Abstract Researchers from diverse disciplines, including organismal and cellular physiology, sports science, human nutrition, evolution ecology, have sought to understand the causes consequences of surprising variation in metabolic rate found among within individual animals same species. Research this area has been hampered by differences approach, terminology methodology, context which measurements are made. Recent advances provide important opportunities identify address key questions...
Summary Development plasticity is a common evolutionary and phenotypic response to poor growth condition, in particular organisms with determinate such as most birds mammals. Because various body structures can contribute differently overall fitness, natural selection will adjust the degree of each structure its proportionate contribution fitness at given life stage. Two non‐mutually exclusive mechanisms account for offspring compensate effect parasites. First, if parasite infestation levels...
Numerous host qualities can modulate parasite fitness, and among these, nutritive resources immunity are of prime importance. Indeed, fitness increases with the amount extracted from body decreases immune response. To maximize parasites have therefore to balance these two components. Yet, because both increase condition, it is unclear whether perform better on hosts in prime, intermediate, or poor condition. We investigated blood meal size survival ectoparasitic louse fly Crataerina melbae...
As fitness returns during a breeding attempt are context-dependent, parents predicted to bias their food allocation within brood from poor towards good condition nestlings when environmental conditions deteriorate. We tested this prediction in the Alpine swift and European starling, two migratory bird species, by modifying an ultraviolet (UV) visual signal of exploring how allocate young as season progresses. show both species that: (i) UV light reflected body skin offspring positively...
Although gene by environment interactions may play a key role in the maintenance of genetic polymorphisms, little is known about ecological factors involved these interactions. We investigated whether food supply and parasites can mediate covariation between degree adult pheomelanin‐based coloration, heritable trait, offspring body mass tawny owl (Strix aluco). swapped clutches nests to allocate genotypes randomly among environments. Three weeks after hatching, we challenged immune system 80...